can you give me the information sheet on coumadin?
611485
GENERIC NAME: warfarin\nBRAND NAME: Coumadin\n\nDRUG CLASS AND MECHANISM: Coumadin is an oral anticoagulant that inhibits the synthesis of clotting factors, thus preventing blood clot formation. Blood clots can occur in the veins of the lower extremities, usually after periods of immobility. These clots can break off and become lodged in the blood vessels of the lung (pulmonary embolism), causing shortness of breath, chest pain, and even life-threatening shock. Blood clots can also occur in the atria of the heart during atrial fibrillation (see Atrial Fibrillation article), and around artificial heart valves. One of these clots can also break off and obstruct a blood vessel in the brain, causing an embolic stroke with paralysis. Coumadin is important in preventing the formation of blood clots. It is also important to prevent extension of clots already formed, and to minimize the risk of blood clot embolization to other vital organs such as the lungs and brain.\n\nPRESCRIPTION: yes\n\nGENERIC AVAILABLE: yes\n\nPREPARATIONS: tablets (1mg, 2mg, 2.5mg, 5mg, 7.5mg, 10mg)\n\nSTORAGE: Store at room temperature in tight, light resistant container.\n\nPRESCRIBED FOR: Coumadin is used in treating patients with blood clots in the lower extremities to prevent extension of the clot, and to reduce the risk of pulmonary embolism. Patients with pulmonary embolism are treated with Coumadin to prevent further blood clot emboli. Coumadin is also used in patients with atrial fibrillation and artificial heart valves to reduce the risk of strokes. It is also helpful in preventing blood clot formation in certain orthopedic surgeries such as knee or hip replacements. Coumadin is also used in preventing blood clot closure of coronary artery stents.\n\nDOSING: Coumadin may be taken with or without food. Since Coumadin is metabolized by the liver and excreted by the kidneys, dosages need to be lowered in patients with liver and kidney dysfunction. Frequent blood tests are performed to measure blood clotting time (protime) during Coumadin treatment. Protime results help doctors adjust medication dose to avoid excessive blood thinning and risk of bleeding.\n\nDRUG INTERACTIONS: Many drugs, both prescription and nonprescription (OTC), can affect the anticoagulant action of Coumadin. Some medications can enhance the action of Coumadin and cause excessive blood thinning and life-threatening bleeding. A few examples of such medications include Aspirin, Tylenol, alcohol, ibuprofen (Motrin), cimetidine (Tagamet), oxandrolone (Oxandrin), certain vitamins, and antibiotics. Patients on Coumadin should regularly consult their doctor before instituting any medications on their own. It is also advisable for patients on Coumadin to carry identifications to alert other health professionals.\n\nPREGNANCY: Coumadin should be avoided by pregnant women or women who may become pregnant. Birth defects and fetal bleeding have been reported.\n\nSIDE EFFECTS: The two most serious side effects are bleeding and necrosis (gangrene) of the skin. Bleeding can occur in any organ or tissue. Bleeding around the brain can cause severe headache and paralysis. Bleeding in the joints can cause joint pain and swelling. Bleeding in the stomach or intestines can cause weakness, fainting spells, black tarry stools, vomiting of blood, or coffee ground material. Bleeding in the kidneys can cause back pain and blood in urine. Other side effects include purple, painful toes, rash, hair loss, bloating, diarrhea, and jaundice (yellowing of eyes and skin). Signs of overdose include bleeding gums, bruising, nosebleeds, heavy menstrual bleeding, and prolonged bleeding from cuts.
924029
You can get it at this site here.\n\nhttp://www.auravita.com/products/aura/PHCO15240.asp?RefId=700&adid=PHCO15240&ref=www.kelkoo.co.uk
779282
The site below gives info about the drug including side effects
86755
I can tell you that it's actually spelled "acenocoumarol." There is a lot of info on the FDA Site:\n\nhttp://www.fda.gov/search.html
215707
sure, rxlist.com\nthere's a section 'for patients/patient information' on every drug, so it's in understandable English :O)
1094883
Go to WebMD.com and put Vicadin in as a keyword and there's a wealth of information on it that might be useful to your research.
447499
You could also try\nwww.rxlist.com\nthey shurely describe the mode of action\n\nFor chemical structures try\nwww.wikipedia.org\nthey should cover a lot of the substances, I guess.
1068416
The test you are refering to is the INR, International Normalized Ratio.  The ratio is derived by dividing the patients PT (prothrombin time) by  the "normal pt."  Also included in the calculation is a variable to adjust for the specific instrument and reagent (throboplastin) used.  The INR is a way to standardize results of PT testing, the INR should remain about the same no matter where the PT was actually done.  The PT is a test of clotting factors.  There are 13 factors working togethor to cause a clot.  The PT measures the effectiveness of those factors dependent on Vitamin K for their production in the liver.  Coumadin is a Vitamin K depressent, resulting in the suppresion of these specific clotting factors and slowing down clot formation.  Prescribed for people at risk for clots and after many types of surgeries, coumadin is not a blood thinner but rathe a drug which suppresses clotting.  Doctor's use the INR to measure the effectiveness of coumadin therapy, referring to the INR is easier and safer than that of the PT because the INR does take into account the possibility of PT testing during the coars of treatment and monitoring being performed on different instruments.  The generic name for coumadin is warfarin, the primary ingredient in rat poison.  The massive dose that a rat gets causes major hemmorhage.  The antidote for coumadin overdose is Vitamin K injections.
1125229
http://www.netdoctor.co.uk/medicines/100002190.html
122144
go to www.webmd.com and type the name in the search box. It will give you all the information you need including side effects interactions mostly everything on the medicine that you want to know.
328683
http://www.indiana.edu/~bradwood/eagles/phosphate.htm\n\nhttp://pronet-internet.merck.de/Attachment/17795.ProNet.pdf?file
882990
Careful!  Warfarin reacts badly with LOTS of vitamins, Minerals, over the counter products and even herbal remedies. \nSome can be fatal!\nDO NOT take anything until you have spoken to your doctor or pharmacist.
595379
try http://www.webmd.com
1165812
Try this link:\n\nhttp://www.amberjewelry.com/Amber_in_Therapeutics_p1.htm
912905
http://www.coshh-essentials.org.uk/\nhttp://www.lshtm.ac.uk/staffdev/Web%20docs/TNAreport.doc\nhttp://www.stotfoldscouts.org.uk/risk/hqrisk.htm\nhttp://www.bio.sdsu.edu/pub/regan/Keithetal2004.pdf
699034
The article on NHS Direct is good and informative about anaemia. The one on dotpharmacy gives lots of info too.
483288
Do a yahoo search on anticoagulation or anticoagulation forum.  There is a great discussion board out there that my nurses use all the time.