During the inflammatory response, what causes arterioles in the damaged are to dilate?
596809
C - Histamine. It is a potent inflammatory vasodilator naturally found in the body. Its function is to increase the supply of blood to an injury or foreign substance that enters the body. Itching, swelling, redness are all effects of histamines.
863861
I believe you are referring to atherosclerosis. The walls of the blood vessels gets damaged making it sticky and easy for fat/cholesterol to be deposited on it. The lumen of vessels gets more constricted and will eventually become blocked. The hardened vessel can also burst as it is loses elasticity.
536978
Causes\nThe precise pathogenesis of rosacea still remains unknown, but most experts believe that rosacea is a disorder where the blood vessels become damaged when repeatedly dilated by stimuli. The damage causes the vessels to dilate too easily and stay dilated for longer periods of time or remain permanently dilated, resulting in flushing and redness. Immune cells and inflammatory mediators can leak from the microvascular bed causing inflammatory pustules and papules, especially with those with papulopustular rosacea.\n\nRosacea has a hereditary component and those that are fair-skinned of European or Celtic ancestry have a higher genetic predisposition to developing it. Women are more commonly affected but when men develop rosacea it tends to be more severe. People of all ages can get rosacea but there is a higher instance in the 30-50 age group. The first signs of rosacea are said to be persisting redness due to exercise, changes in temperature, and cleansing.\n\nTriggers that cause episodes of flushing and blushing play a part in the development of rosacea. Exposure to temperature extremes can cause the face to become flushed as well as strenuous exercise, heat from sunlight, severe sunburn, stress, cold wind, moving to a warm or hot environment from a cold one such as heated shops and offices during the winter. There are also some foods and drinks that can trigger flushing, these include alcohol, foods high in histamine and spicy food.\n\nCertain medications and topical irritants can quickly progress rosacea. If redness persists after using a treatment then it should be stopped immediately. Some acne and wrinkle treatments that have been reported to cause rosacea include microdermabrasion, chemical peels, high dosages of isotretinoin, benzoyl peroxide and tretinoin. Steroid induced rosacea is the term given to rosacea caused by the use of topical or nasal steroids. These steroids are often prescribed for seborrheic dermatitis. Dosage should be slowly decreased and not immediately stopped to avoid a flare up.\n\nStudies of rosacea and demodex mites have revealed that some people with rosacea have increased numbers of the mite, especially those with steroid induced rosacea. When large numbers are present they may play a role along with other triggers.
98448
Occupational exposure to any fumes and/or chemicals can create inflammatory responses within your lung tissue. When this inflammation occurs on a daily basis over a several year period, your lung tissue, specifically the parenchyma will become damaged similiar to that of a chronic smoker. The parenchyma is the distal portion of your lungs that partake in gas exchange (Co2 and 02), when this layer of blood vessels and tissue become destroyed, there is no way to repair the damage. Just think of a coal miner's lung
798418
depends on what blood vessels were enlarged, how enlarged, pressing on some other anatomical structures etc, ask your doctor to explain how were they causing the pain, he/she should be able to explain the pathophysiology accordingly, good luck
777209
Your body makes molecules that stimulate inflammation (pain, swelling, etc.) To make these molecules you body uses an enzyme called cyclooxygenase (COX) and aspirin blocks this enzyme so that the inflammatory mediators don't get made.
385161
because things dilated when is warm
493685
Get to a Dr., NOW !!!!!!\nYou might have a broken blood vessel.
740317
Actually you'd be surprised as to the various types of disease that are related to the inflammation of the blood vessels and most of them have serious consequences.  I'm trying to determine if that is a sarcastic question or are you really looking for a type of doctor who treats vessel disease.  But an Internal Medicine doctor or vascular surgeon will treat them.
285600
Hmmm, good question.  I guess I automatically assumed capillaries, but they might not be small enough to be considered capillaries.  On second thought, I'd go with arterioles because these vessels have oxygenated blood in them (meaning they came from the heart), are too small to be arteries but not small enough to be capillaries, and are obviously not viens.
1077836
none salt cause high bloodpressure and stress
1105495
3 major factors Pump, volume, and container.\n\nPump (The heart) when damaged is unable to pump sufficiently to maintain systemic pressure.\n\nLow systemic volume( Hypovolemia) can be caused by numerous factors such as excessive vomiting, dehydration, blood loss due to trauma, excessive sweating, etc.\n\nYour blood vessels (container) dilate and constrict based on many factors. For example when scared, your vessels vasodilate (expand) creating more space in the container and thus lowers blood pressure.
1020074
thats what would happen in a healthy individual because of peripheral vasodilatation.\n\nin sick people the vessels arent as elastic so the heart rate goes up, and the vessels calibre stays the same so their pressure goes up.
408531
It's spelled arteriosclerosis if you are looking it up. It's a deposite of cholesterol and fats on the inner surface of arteries. If you can imagine how gunk might build up over time on the inner wall of a pipe, you have a good mental picture.\n\nArteriosclerosis can lead to problems in many ways, some of which are that the artery becomes less flexible and cannot respond as well to blood pressure changes. Pieces of plaque can break off and cause blockages 'downstream' when the size of blood vessels gets smaller. The plaque can irritate and cause inflammation of the artery wall which can lead to scaring and rarely, leaks. Over time, the plaque can build up so much that it starts to restrict the blood flowing through that artery and depending where the problem occurs, can lead to such things as stroke or heart attack.
185017
Altered hemodynamic response to isosorbide dinitrate in essential hypertension\nBM Pannier, T Kando, AA Safarian, RN Isnard, BE Diebold, and ME Safar\n\nRelaxation produced by nitrates on venous, arteriolar, and large arterial vessels is well known but has never been studied in human hypertensive aortas studied in vivo. In this investigation, the effects of acute oral administration of 20 mg of isosorbide dinitrate were evaluated in 12 patients with sustained essential hypertension and nine normotensives of the same age. Noninvasive measurements of systolic, diastolic, and mean arterial pressure, carotid-femoral pulse wave velocity and aortic-arch diastolic diameter using suprasternal echocardiography were determined before and 3 hours after drug administration. In normal subjects, isosorbid dinitrate significantly decreased systolic blood pressure and pulse pressure but did not affect diastolic and mean arterial pressure. In contrast, in hypertensives, the same dosage of isosorbid dinitrate decreased together systolic, diastolic mean, and pulse pressure. In both populations, pulse wave velocity decreased significantly whereas aortic arch diastolic diameter increased markedly. The increase was observed mainly in normal subjects. The study provided evidence that (1) both in normal subjects and hypertensives, isosorbide dinitrate caused an increase in aortic diameter together with an increase in arterial distensibility; and (2) the changes in mean arterial pressure were significant only in hypertensives, indicating that the altered vasodilator response in essential hypertension is not endothelium-mediated
513507
The pressure in their vessels is high already.  If you add excess salt to your diet your body tries to reach a hemostatic equilibrium by retaining water.  Eventually too much water is kept in the vessels, the pressure increases more and a vessel somewhere bursts.  The most damaging areas are in the brain (causes a stroke and increased intercranial pressure), lungs (causes pneumonia), and the heart (causes heart failure).
434673
Arteries are composed of three layers. The middle layer is smooth muscle, and it works to control blood flow maintain blood pressure. The inner layer is made up of a smooth layer of endothelial cells which allow blood to flow freely through the artery.\n\nAs you age, the inner layer of endothelium becomes leaky, whichs allows fats and toxins to pass through the endothelial layer and into the smooth muscle cells. Your body mounts an immune response against these molecules, which causes the wall of the artery to become inflammed. \n\nIn an effort to plug the holes, the smooth muscle cells begin to produce a collagen cap over the leaks. Eventually, a plaque forms. Vascular calcification occurs when calcium is deposited on these plaques, causing a hardening of the arterial wall. If the plaque is loosened and breaks free into the blood stream, it can cause a stroke or heart attack.