Ways to identify disease gene?
489224
positional cloning is finding the location of the disease gene. linkage analysis is used. usually a marker is used to narrow down the location to 10Mb. the marker can be STR, defective enzyme that are always linked to the disease. then more marker are chosen near the site to further narrow down the range. then cloning of the region is done. if DNA can be hydridize to RNA library to see which gene it coded for. from the gene found, there should be one with mutation in and it si possibly your target\nfunctional cloning is used when you know the pathology of the disease so that you know the protein (gene product of your target). the protein can be cleaved. sequenced. and generate cDNA to probe the genome for the gene\npostional candidate is used when you have idea of the pathology. first you find the subchromosomal location of the gene jist as positional do, but you dun need to narrow down the region as it take many works. then from the region you find out if there is any gene that may cause the disease\nfor example, you target rodopsin if you wantto find an eye disease. this method is certainly better than postional\ncandidate is you find the homologue in other species \nby studying the disease that cuse same phenotype \nto give you some clues of the gene
604807
In regards to what? Blood? Sex typing? Genes? Cars? You need to be more specific!!
1181866
there are databases with which you can do homology searches. best to know what genes you are looking for though as genome wide homology may be difficult to search for\ntry the ensemble database:\nhttp://www.ensembl.org/index.html\notherwise a broad literature search might be better suited. odds are someone else has already done a similar comparison.\n\nfound this old review\n\nhttp://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6VS0-45765F9-2J-1&_cdi=6248&_user=911953&_orig=search&_coverDate=06%2F30%2F1997&_qd=1&_sk=999929996&view=c&wchp=dGLbVtz-zSkWA&md5=03f894feac6d92afb553850237f34bcf&ie=/sdarticle.pdf\n\nmight be of some help. if the link doesnt work, can be found using a Pubmed search.
708612
The question is too general.  It depends on what type of gene you are asking about.  For gene related to human diseases, one most likely will need to study patient population with the disease and consider are the gene(s) playing equal role in different patients.  Human diseases often involve many genes and they are likely involved in a common pathway for example.  Defect in any component of a pathway may generate the same disease phenotype.  \n\nIf there is a great animal model for the human disease, investigators will likely use the model to determine disease gene.  However, very often the gene affected in animals is not exactly the same that causes problem in human.  \n\nIf, however, you mean gene of interest in a bacteria, the ball game is quite different.  It is much more easy to work with simple organism.  One can isolate mutants affecting the gene of interest.
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hybridization.com\n\nor just type the keyword and the information you needed wud appear..
89543
r methyl viologen \n\nwow..this was a hard one\n\nIt appears to be used in Genome research.
290005
You can draw your family tree and name all of your closest family, including siblings, parents and grandparents.  If someone has died, mark the age and cause of death.  Then just go through everyone on the tree and ask them what diseases they are suffering from.  Hope that helps!
527137
Medical Therapy.\n1- Cells can be engineered to produce a pathogen's surface protein, which can be used as a subunit vaccine. \n\n2-Synthetic genes linked to the β-galactosidase gene in a plasmid vector were inserted into E. coli, allowing E. coli to produce and secrete the two polypeptides used to make human insulin. \n\n3-DNA probes can be used as rapid diagnostics to identify a pathogen quickly in body tissue or food. \n\n4-Genetic screening uses Southern blotting to look for mutations responsible for inherited disease in humans.\n\nAny Help?
226270
identification of tribe and parentage
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There are certain identifiable characteristics that can be found in some blood samples. The most prominent example is Sickle Cell anemia.  \nThat's just from blood. However, from DNA markers, it is possible to identify certain genomes that would give you a pre-disposition to certain races.  It may not be a definative race, but it could narrow down possibilities until you can come up with a high probability.
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Go to www.genesreunited.com
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This should keep you busy for hours.....\nhttp://en.wikipedia.org/wiki/List_of_genetic_disorders
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gene:\nhttp://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=46561731\nhttp://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=10444342\nhttp://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=311024\nhttp://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=48496\nhttp://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=155319\nhttp://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=155317\n\nPCR:\nhttp://www.protocol-online.org/prot/Molecular_Biology/PCR/Standard_PCR/index.html
281677
store information about the cell. its mostly hereditary.
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try www.ncbi.org/com (i forget)
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REFER TYHIS WEB ADDERESS\nhttp://www.genwaybio.com
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Current treatments - problems, advantages\n\nPossible future treatments\n\nInheritance patterns and genetic counselling.\n\nHistory of discovery of the disease or its history in general.\n\nphysiological and genetic basis of the disease (talk about clotting factors).\n\nPerhaps a mixture of the above topics in the one speech in a logical order.