the genetic disease caused by maternal nondisjunction of the autosome is?
464570
down's syndrome is a disease that results from gaining an extra autosome through nondisjunction.  It effects autosome 21.
1118027
This is like asking Why are there so many different kinds of flowers, there is no one answer for this question. Sometimes the mother makes poor or uneducated choices during pregnancy or isn't aware of being pregnant; poor neutrition, smoking, drugs, exposure to certain drugs and chemicals will negatively affect the developing baby. Generally in this situation there is damage to the tissues of the developing baby stopping things from proceeding normally.  \n\nSometimes, genetics affect the embreo in the same way identical twins develop. Genetics are the "roadmap" that tells the cells what to be and where to go. Sometimes genetics tells the egg to seperate making two identical babys, but sometimes there are flaws in the "roadmap"   and things don't develop or don't develop properly.  \n\nSometimes there is no reason at all for the disability. It's a sad start to life but good parents will help the child to make the most of their situatin and lead a productive life.
384876
it is a genetic disorder caused by having 3 chromosome #18s instead of 2. this is called trisomy 18. (down sydrome is caused by trisomy 21). \n\nover 90% of these babies have major heart defects. more than half are deaf. they require very intense care at birth, have a high risk of dying, and have major medical and developmental problems if they survive.
1094022
Probably not genetics, probably having abusive parents.
73136
Hmm....\nthere are mainly two types of chromosomal mutation\nchanges in the structure and changes in the number of chromosome\n\nin the case of the first, changes in the structure, \nthere are four types\ndeletion, duplication, inversion and translocation\n\nwhile for the 2nd, are mainly cause by non-disjunction
260970
Yes, it is XYY and it is uncommon.  However, if you have this abnormality, you are unlikely to ever know it.  The tendency to violence with this abnormality is largely discredited, most evidence shows no abnormal tendencies in these people.  See the website below for more information and read the special chapter in the referenced book for an even more fascinating analysis of this question.\n\nEdit:\nI have looked into it a bit more and have found that the name of the condition is Jacobs Syndrome.  As to the question about whether it is possible, it certainly is possible.  It happens during meiosis II, when there is nondisjunction of sister chromatids of the Y chromosome, resulting in both sister chromatids in one cell and none in the other cell.  Nondisjunction means that the chromatids are normally supposed to split apart, one going into each cell, but that doesn't happen.
1026236
After the egg has been fertilized it begins to divide.  In Metaphase of cell division the chromosomes line up on the equator and get ready for their migration to the poles of the cell.  The problem occurs in the next phase, telophase, this is when the identical chromosomes are being pulled away to opposite ends, what happens is one pair of chromosomes gets stuck and  do not seperate and both are pulled to one side of the cell.  This is called non-disjunction.  The most commonly known genetic disease in which this happens is  Down's Syndrome, also known as Trisomy 21.  The normal number of the #21 chromosome is supposed to be 2 but because of non-disjunction, one extra #21 gets copied.\n\nTrisomy is a genetic diseased caused by non-disjunction of the chromosomes during Mitosis/Meiosis.
123745
There are 3 chromosomal patterns that result in Down syndrome. 1. Trisomy 21 (nondisjunction) is caused by a faulty cell division that results in the baby having three #21 chromosomes instead of two. ... In translocation a part of chromosome #21 breaks off ... division and attaches to another chromosome. The presence of ... the 21st chromosome causes the characteristics of Down syndrome
301931
umm, though i'm not sure what the question really says- i think you are asking about genetic diseases involved with chromosome number, if i'm right the following stands, if not then ignore it. \nif you have less or more chromosomes than 46 you will not survive far past fertilization, at least thats what i understand- either that, or you would be a different species- unable to produce a fertile offspring with a human.\n\nHowever there is a lot of confusion around Down's syndrome. This is caused by non-disjunction of chromosomes during meiosis, and creates trisomy genotypes on chromosome 21. \n\nTrisomy and non-disjunction can also occur on chromosome 17- causing another disease, which i have momentarily forgotten the name of. sorry.
71183
Genetics, scientific study of how physical, biochemical, and behavioural traits are transmitted from parents to their offspring. The word itself was coined in 1906 by the British biologist William Bateson. Geneticists determine the mechanisms of inheritance whereby the offspring of sexually reproducing organisms do not exactly resemble their parents, and the differences and similarities between parents and offspring recur from generation to generation in repeated patterns. The investigation of these patterns has led to some of the most exciting discoveries in modern biology.\nSoon after Mendel's work was rediscovered, scientists realized that the patterns of inheritance he had described paralleled the action of chromosomes in dividing cells, and they proposed that the Mendelian units of inheritance, the genes, are carried by the chromosomes. This led to intensive studies of cell division.\n\nEvery cell comes from the division of a pre-existing cell. All the cells that make up a human being, for example, are derived from the successive divisions of a single cell, the zygote (see Fertilization), which is formed by the union of an egg and a sperm. The great majority of the cells produced by the division of the zygote are, in the composition of their hereditary material, identical to one another and to the zygote itself (assuming that no mutations occur; see below). Each cell of a higher organism is composed of a jellylike layer of material, the cytoplasm, which contains many small structures. This cytoplasmic material surrounds a prominent body called the nucleus. Every nucleus contains a number of minute, threadlike chromosomes. Some relatively simple organisms, such as cyanobacteria and bacteria, have no distinct nucleus but do have cytoplasm, which contains one or more chromosomes.\n\nChromosomes vary in size and shape and usually occur in pairs. The members of each pair, called homologues, closely resemble each other. Most cells in the human body contain 23 pairs of chromosomes, whereas most cells of the fruit fly Drosophila contain four pairs, and the bacterium Escherichia coli has a single chromosome in the form of a ring. Every chromosome in a cell is now known to contain many genes, and each gene is located at a particular site, or locus, on the chromosome.\n\nThe process of cell division by which a new cell comes to have an identical number of chromosomes as the parent cell is called mitosis (see Reproduction). In mitotic division each chromosome divides into two equal parts, and the two parts travel to opposite ends of the cell. After the cell divides, each of the two resulting cells has the same number of chromosomes and genes as the original cell (see Cell: Division, Reproduction, and Differentiation). Every cell formed in this process thus has the same genetic material. Simple one-celled organisms and some multicellular forms reproduce by mitosis; it is also the process by which complex organisms achieve growth and replace worn-out tissue.\n\nHigher organisms that reproduce sexually are formed from the union of two special sex cells known as gametes. Gametes are produced by meiosis, the process by which germ cells divide. It differs from mitosis in one important way: in meiosis a single chromosome from each pair of chromosomes is transmitted from the original cell to each of the new cells. Thus, each gamete contains half the number of chromosomes that are found in the other body cells. When two gametes unite in fertilization, the resulting cell, called the zygote, contains the full, double set of chromosomes. Half of these chromosomes normally come from one parent and half from the other.\n\nFor more than 50 years after the science of genetics was established and the patterns of inheritance through genes were clarified, the largest questions remained unanswered: how are the chromosomes and their genes copied from cell to cell, and how do they direct the structure and behaviour of living things? Two American genet
504096
Presumably you don't mean monosomy X? Monosomy 10 seems to be something associated with some types of tumor cells not with a genetic disorder at birth
138180
nondisjunction\nOne entry found for nondisjunction.\nMain Entry: non·dis·junc·tion\nPronunciation: "nän-dis-'j&[ng](k)-sh&n\nFunction: noun\nEtymology: International Scientific Vocabulary\n: failure of homologous chromosomes or sister chromatids to separate subsequent to metaphase in meiosis or mitosis so that one daughter cell has both and the other neither of the chromosomes\n- non·dis·junc·tion·al /-shn&l, -sh&-n&l/ adjective
695108
First you have to make out your alleles.  Your first parent PpLl will produce spermatozoids that can be either PL Pl pL pl.  As for the mother, she is also heterozygotous for both traits, so she is also PpLl and will produce eggs that are either PL Pl pL or pl.  The you make the Punnett square with all those four colomns and four rows.  You should get something like\n___|_PL__|_Pl_|_pL_|_pl__\nPL_|_PPLL|_PPLl_|_PpLL_|_PpLl_\nPl_|PPLl|_PPll_|_PpLl_|_Ppll_\npL_|PpLL_|_PpLl_|_ppLL_|_ppLl_\npl_|PpLl_|_Ppll_|_ppLl_|_ppll_\n\nOKAY NOW...\nPPLL means healthy all the way\nppll means has all the diseases\nIn between they are heterozygotous for one or both disease.\n\nSince you have 16 possibilities, then yes your 1/16 answer is correct for the probabilities of having both diseases\n\ncan you do the square for your second problem :-)
687997
Causes\n \nX-linked recessive inheritanceThe fragile X syndrome is a genetic disorder caused by mutation of the FMR1 gene on the X chromosome. Mutation at that site is found in 1 out of about every 4000 males and 1 out of about every 6000 females.\n\nNormally, the FMR1 gene contains between 6 and 53 repeats of the CGG codon (trinucleotide repeats). In people with the fragile X syndrome, the FMR1 allele has over 230 repeats of this codon.\n\nExpansion of the CGG repeating codon to such a degree results in a methylation of that portion of the DNA, effectively silencing the expression of the FMR1 protein.\n\nThis methylation of the FMR1 locus in chromosome band Xq27.3 is believed to result in constriction and fragility of the X chromosome at that point, a phenomenon that gave the syndrome its name.\n\nMutation of the FMR1 gene leads to the transcriptional silencing of the fragile X-mental retardation protein, FMRP. In normal individuals, FMRP binds and facilitates the translation of a number of essential neuronal RNAs. In fragile X patients, however, these RNAs are not translated into proteins. The various sequelae of fragile X syndrome .\n\n[edit]\nTransmission of the Fragile X\nThe diagram (right) of X-linked recessive inheritance is not entirely inappropriate but it markedly oversimplifies the situation and does not provide a sufficient foundation for genetic counseling about the fragile X syndrome.\n\nBecause males normally have only one copy of the X chromosome, those males with significant trinucleotide expansion at the FMR1 locus are symptomatic. They are mentally retarded and may show various physical features of the fragile X syndrome.\n\nFemales have two X chromosomes and thus have double the chance of having a working FMR1 allele. Females carrying one X chromosome with an expanded FMR1 gene can have some signs and symptoms of the disorder or be normal.\n\nMales with the fragile X cannot transmit it to any of their sons (since males contribute a Y chromosome, not an X, to their male offspring.)\n\nFemales carrying one copy of the fragile X can transmit it to their sons or daughters. Sons who receive the fragile X are at high risk for mental retardation. Daughters who receive the fragile X may appear normal or they may be mentally retarded, usually to a lesser degree than boys with the syndrome.\n\nIt can begin at birth
869008
It can be either.\n\nIt most commonly exhibits familial transmission consistent with autosomal dominant (AD) inheritance (approximately 90%), but X-linked (5-10%) and much less commonly autosomal recessive (AR) or mitochondrial inheritance have been reported.
380018
From what I have read, it appears that it is autosomal dominant and is not X-linked as the gene most likely responsible lies on chromosome 1.\nHope this helps
217625
I'm reluctant to apply those terms to a chromosomal abnormality.  Cri Du Chat results from partial monosomy of chromosome 5 (i.e. part of one copy of the chromosome of missing).  An invidual doesn't have an allele per say, so there's no real heterozygous genotype.  The genotype that results in the Cri Du Chat phenotype is defined by the presences of exactly one copy of the short arm of chromosome 5.  I think the reason you haven't been able to find the answer is that there isn't one.