how does acetaminophen work?
402223
Acetaminophen appears to interfere with the action of prostaglandins, substances in the body that cause inflammation and make nerves more sensitive to pain impulses. It also relieves fever, probably by acting on the heat-regulating center of the brain.\n\nIt takes aprox. half an hour to fully take effect depending on the current contents of ones stomach
432108
How Anesthesia Works\nhttp://health.howstuffworks.com/anesthesia.htm
189960
The 'pm' part of Tylenol pm is Benadryl (diphenhydramine) which is an antihistamine.  Some people do have a restless feeling associated with taking antihistamines in higher doses.  As another person who answered this question rightly pointed out, Tylenol taken in high doses can be toxic to your liver.  To be safe be sure your total intake of Tylenol does not exceed 4 grams per day (1 extra strength Tylenol = 0.5 gram).  Seriously, back off on all of that Tylenol.  If you are taking them for the sleep-inducing effect then consider taking benadryl alone - it is a pretty safe medication but anything has the potential to cause harm if you ingest enough.\n\nNow for the real issue - why aren't you sleeping?  It may make sense for you to consider the elements of 'sleep hygeine.'  In short, sleep hygiene are things you can do without medication to enhance your own ability to sleep - like eliminate caffiene, exercise, etc.  Try doing a search on any search engine for the list.  Follow the advice strictly for a couple of weeks before you decide if its working or not.  These are good habits to adopt for a lifetime, regardless.  If it is not working then consider making an appointment with your doctor to discuss and treat your condition further.  Sweet dreams.
745161
A can of Coke in the morning with a tylenol or two. Eat someting but no heavy meals. And drink lots of fluids like water and fruit juices.
889598
I am a pharmacist in consulting practice.\nYes this is a real problem and if you have within the past several months purchased caplets of generic Tylenol (known as acetaminophen) I would put it aside and purchace a 30 day supply of BRAND NAME PRODUCT (made by McNeil) Tylonol.  This probelm could effect generic acetamionphen from many different stores.  There were and estimated 11 Millon bottles of product involved.  Part of the issue here is the overall quality and reliability of any generic product.\n\nAttached for your reference is a copy of an ALERT issued by the American Pharmacist Association in Washington DC to its membership on this problem:\n\n"Metal fragments result in large acetaminophen recall\nPerrigo, supplier of store brands to dozens of retailers, says metal fragments might be in caplets of 11 million bottles; FDA investigating.\n\nA recall announced this morning by FDA affects some 11 million bottles of store-brand acetaminophen distributed nationally, including many large retailers such as Eckerd, Fred Meyer, Kroger, Long’s Drug Stores, McKesson, Publix, Ralph’s, Safeway, and Wal-Mart. Conducted by Perrigo Company of Allegan, Mich., the recall affects 383 lots of acetaminophen 500 mg caplets and resulted from presence of small metal fragments found in a few of these caplets.\n\nTo date, no illness or injuries related to this problem have been reported, and no consumers have complained to FDA or Perrigo. Based on information currently available, FDA believes the probability of serious adverse health consequences is remote; if a consumer were to swallow a caplet containing metal fragments, it could cause minor stomach discomfort and/or possible cuts to the mouth or throat. Consumers should consult their physician if they suspect they’ve been harmed by use of this product.\n\nConsumers who believe they are in possession of the affected products (see links below for lot numbers and store brands) should discontinue use immediately and call Perrigo’s Consumer Affairs Department at 877-546-0454 for further instructions. Any adverse reactions experienced with the use of this product should be reported to Perrigo at the above number and the FDA’s MedWatch Program by phone at 800-FDA-1088, by fax at 800-FDA-0178, or on the MedWatch Web site \n\nFDA is currently investigating the cause of the metal particles found in the acetaminophen 500 mg caplets. Perrigo originally informed FDA of this problem after discovering through their own regulatory quality control procedures that their tablet-making equipment was wearing down prematurely. The company is also investigating the cause of the problem. The ongoing investigations have revealed the presence of the metal fragments in these caplets. Perrigo reported to the FDA that 70 million caplets were passed through a metal detector, and this resulted in the discovery of approximately 200 caplets containing metal fragments ranging in size from "microdots" to portions of wire 8 mm in length.\n\nAt this time FDA does not anticipate that this action will cause a shortage of acetaminophen. Currently, only one strength (500 mg caplets) is affected. Consumers may wish to take additional amounts of the lower strengths of acetaminophen tablets or caplets, which are not affected by this recall, to reach the 500 mg dose or use acetaminophen produced by other manufacturers. In all instances, FDA advises consumers to follow labeled instructions for maximum daily dosage.\n\nPerrigo is notifying its distributors and retailers of this issue and will inform them of steps it will take to facilitate product replacement."
805706
If you take a lot of aspirin it just turns to poison inside you and your liver starts frantically trying to get rid of everything before it causes damage to other organs. Unfortunately your liver takes a beating from this and might just decide that it's all too much and give up. If that happens, you will experience acute liver failure and you will very likely die if you do not immediatly receive a liver transplant.\n\nThis is caused by a chemical called acetaminophen which is found in Panadol and Aspirin.\n\nAlso, if you drink alchol or eat foods with a lot of sodium in them (Think salty, savoury foods) then you will likely experience extreme brain damage or death.\n\nI knew somebody who took a lot of painkillers that had  acetaminophen in it and she was moment away from a liver failure. She is now unable to drink alcohol for a year, if not longer.\n\nPS I don't think you will get very sick from just 7 aspirins but you may get a bad headache and feel queasy. If you did take them, don't drink any alcohol because that will make it a lot worse and may cause damage to your body.
45828
For starters Drowsyness \n\nok here we go \nSIDE EFFECTS: Nausea, vomiting, constipation, lightheadedness, dizziness, drowsiness, flushing, vision changes, or mental/mood changes may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: slow/irregular breathing, slow/irregular heartbeat, change in the amount of urine. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: impairment or loss of hearing (especially with high doses for long periods). If you do not have liver problems, the adult maximum dose of acetaminophen is 4 grams per day (4000 milligrams). If you take more than the maximum daily amount, it may cause serious (possibly fatal) liver disease. Tell your doctor immediately if you have any of the following symptoms of liver damage: severe nausea, yellowing eyes or skin, dark urine, stomach pain, extreme fatigue. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist\n\nhttp://www.medicinenet.com/hydrocodoneacetaminophen-oral/article.htm\nsection juss for side effects
414975
They are both the same medication, one just delivers to your body faster. No problem. However, acetomenophen is hazardous to you liver if you drink.
152041
Take 800 mg of Ibuprofen which is prescription strength.  It has an anti-inflammatory in it so it's going to work better than Tylenol or aspirin.
828103
Paracetomol is soluble in organic solvents such as methanol and ethanol but is only sligtly soluble in water. The resulting glucuronide has a much higher water solubility than the original substance and is eventually excreted. \n\nParacetamol is metabolized primarily in the liver, where most of it (60-90% of a therapeutic dose) is converted to inactive compounds by conjugation with sulfate and glucuronide, and then excreted by the kidneys. Only a small portion (5-10% of a therapeutic dose) is metabolized via the hepatic cytochrome P450 enzyme system (specifically CYP2E1); the toxic effects of paracetamol are due to a minor alkylating metabolite (N-acetyl-p-benzo-quinone imine, abbreviated as NAPQI) that is produced through this enzyme, not paracetamol itself or any of the major metabolites. The metabolism of paracetamol is an excellent example of toxication, because the metabolite NAPQI is primarily responsible for toxicity rather than paracetamol itself.\n\nGlucuronidation is the process of chemically binding a substance to glucuronic acid via a glycosidic bond. The resulting glucuronide is typically much more water soluble than the original substance. The human body uses glucuronidation to excrete a large variety of molecules, including drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids and bile acids. Most of this is done by the liver.\n\nAt usual doses, the toxic metabolite NAPQI is quickly detoxified by combining irreversibly with the sulfhydryl groups of glutathione to produce a non-toxic conjugate that is eventually excreted by the kidneys.
273796
I think you meant Coricidin. Coricidin has 2 drugs in it: Acetaminophen and Chlorpheniramine. Acetaminophen won't make you "high" its just tylenol, but Chlorpheniramine is an antihistamine that effects many receptors in your body. I'd say that is what gives you the high feeling.
612069
Do mean Efferalgan?\n\nEfferalgan is a brand name for acetaminophen, also know as paracetamol.\n\nI is a pain relief medication used for mild to moderate pain.\n\nIn the USA a well know brand name is Tylenol
462564
ACETAMINOPHEN/PHENYLTOLOXAMINE \nThis combination medication is used to treat the minor aches and pains (e.g., headache, backache, toothache, joint pain, cramps) associated with menstrual periods, colds, flu, dental problems, or arthritis. It is also used to reduce fever.\nSee in\nhttp://www.medicinenet.com/acetaminophenphenyltoloxamine-oral/article.htm
1120352
Acetaminophen - Cumulative Effect Can Cause Acute Liver Failure (Keep reading the dosage alert is at the bottom.\n\nAcetaminophen, commonly known as Tylenol, is regarded as one of the safest pain relievers. Reportedly, over 100 million people/year take acetaminophen for various painful conditions, including arthritis. Liver damage occurs in a relatively small number of people who take acetaminophen, yet accidental overdose and acute liver failure caused by acetaminophen is recognized as a growing problem. Though labels of products containing acetaminophen disclose how much of the ingredient is in the product, some people put themselves at risk by not keeping track of their total daily intake of acetaminophen.\n\nAcetaminophen is in many narcotic drugs available only by prescription, such as Darvocet, Vicodin, and Percocet. Acetaminophen is also in many over-the-counter headache, cold, sinus, and flu medications. The total acetaminophen intake per day must be tracked. It is recommended that adults take no more than 4,000 mg/day of acetaminophen (the equivalent of 8 extra-strength 500 mg tablets or capsules). Because acetaminophen is considered "safe", patients are too often careless about their total daily intake.
949050
Excedrin comes in several different formulas (Extra Strength, Sinus, Migraine, PM, Tension). If you are taking Excedrin Extra Strength, the active ingredients are aspirin, acetaminophen, and caffeine. These ingredients are safe in moderation, but each carries its own set of cautions if taken in large doses or for extended periods of time. Basically, too much aspirin can inhibit blood platelets from doing their job, so you run a higher risk of internal bleeding. Too much acetaminophen can damage your liver. Too much caffeine can raise blood pressure. Contact your doctor for specific advice specific about your symptoms and recommended treatment.
759145
all the answers you have are very close.. but here  is the real deal. oxycodone is the generic name for Oxycontin a powerful pain medication, most of the information about it you have received is correct i wont repeat it. HOWEVER...Percocet is a combination of oxycodone and acetaminophen, a different less powerful drug. any questions you have about your medication should be directed to your pharmacist or physician.. advice here is helpful.. but not always accurate.
774626
This legislation came into force on 16 September 1998.\n\nIt limits the maximum pack size of solid doses of paracetamol and aspirin for general sale to 16 tablets or capsules. It also limits the maximum pack size of solid doses of paracetamol and aspirin to 32 tablets or capsules in pharmacies.\n***The sale or supply of more than 100 aspirin or paracetamol tablets or capsules at one time requires a doctor's prescription.\nThe sale of more than one pack is not illegal, but where it resulted in an overdose the adverse publicity would of course be serious for the vendor.***\nThese measures will not stop anyone from going from shop to shop to buy as many packets as they wish. However, since the purpose of these changes is to reduce the quantities of these products stored in the home, it would be sensible to limit general sale of paracetamol or aspirin to one pack at a time.\n*****Some retailers have introduced a Code of Practice or have programmed their tills to prevent multiple sales.******