If two normal parents with no history of cystic fibrosis in their family have a child with the disease...?
355921
Actually, if two people produce a child with Cystic Fibrosis then they are both carriers of the gene. That means that everytime they reproduce there is a 1 in 4 chance that their offspring will have Cystic Fibrosis. \n\nBasically, it is a genetic matrix. Each parent donates 2 genes to the process. Each parent has one healthy gene and one CF gene. There are four possible genetic combinations when two people with the Cystic Fibrosis gene have a child. \n\nThe child could get one healthy gene from each parent and the child will not develop Cystic Fibrosis. \n\nThe child could receive one healthy gene from his mother and one CF gene from his father and the child will not develop Cystic Fibrosis. \n\nThe child could receive one healthy gene from his father and one CF gene from his mother and the child will not develop Cystic Fibrosis. \n\nThe child could get one CF gene from each parent and the child will develop Cystic Fibrosis. \n\nThere are two important things to remember.\n\nFirst, if the child receives a CF gene from his parents he has the potential of passing that gene on to his children. This is especially true if he were to have a child with a woman who also carries the gene.\n\nSecond, this does not mean that if a couple were to have four children only one would be at risk of having Cystic Fibrosis. The odds start all over with each pregnancy. It's like having a little sack with 3 red marbles and 1 blue marble in it. If you take a marble from the sack and it is red but place the marble back in before you draw again, you have an equal chance of pulling that red marble the second time (just like the first time).
170122
first of all cystic fibrosis is not an infectious disease, i don't know why it is in this category\n\nif you have cystic fibrosis you have the gene so it means you have had it since you were concieved, but the sign and symptoms may not show until mid-teens or even later in mid-20's. so that is when it is diagnosed. but this is very rare and the symptoms usually begin around the ages 5 or 6.
552790
"At least 97% of men with CF are sterile due to congenital bilateral aplasia of the vas deferens (CBAVD), an absence of the vas deferens. There are new technologies that are offering hope to men with CF who desire to father a child since sperm is present. This would involve aspiration and In vitro fertilization. Having a discussion with a fertility specialist would be helpful in those cases. Additionally, men who do not have cystic fibrosis but are born with congenital absence of the vas deferens have an increased risk being carriers of the CF gene.\n\nWomen with CF may also have impaired fertility, as thicker cervical mucus may prevent sperm from entering the uterus and thus reduce the likelihood of unassisted conception"
907371
I know of a family that had 4 kids......they were first cousins, and they ended up having 4 kids with learning disabilities....and downs syndrome......\n\nSo I would say no...do not have kids unless you are prepared to have kids with many challenges.....
361620
I think the reason why you are asking is because of possible birth defects, my advice would be that they should at least be informed on the possible consequences of producing an offspring that had the same illness. Birth Control as well as genetic counseling can help.
222852
a dominant genetic disorder only requires one copy of the causitive gene, so if one of your parents had one copy of the gene and the other none, you would have a 50% chance of getting it. if its recessive, it takes two copies of the gene to actually have the disease, so both parents would both have to have a causitive gene. so dominant usually affects every generation, while recessives usually skip and are less frequently manifested. thats if its autosomal (meaning not on a sex chromosome). if its X-linked, then it gets more complicated. see the link below (pages 4-9) for more help and examples of diseases.
645084
Due to cytoplasmic inheritance.
624944
The cause of cystic fibrosis is related to an abnormality in the gene found on chromosome 7. The cause of cystic fibrosis is inherited in an autosomal resessive (pertaining to a chromosome that is not a sex chromosome) fashion.\n\nCystic fibrosis is seen most commonly in Caucasians.\n\n The cause of cystic fibrosis results in a decrease in chloride secretion across membranes and epithelial surfaces, associated with excess of sodium resorption.\n\n This results in thick secretions in the respiratory tract, and pancreas. These patients also develop dysfunctional male reproductive tracts characterized by obstruction of the vas deferens (vas deferens is a narrow, muscular tube that connects the testicles to the urethra).
692131
PLEASE I URGE YOU TO TAKE HER TO HER PEDO DR, POSSIBLY HAVE AN ULTRSOUND OR CHEST XRAY DONE, DOES SHE HAVE A RATTELY BREATHING SEQUENSE?? ARE THERE ANY ABNORMALITIES IN YOUR FAMILY, THINK HARD....GOOD LUCK... HOPE ALL GOES WELL!
341693
The mother and child will have *nearly* identical DNA.  There will be a few mutations because mutations are ubiquitous, but 99.99+% of their DNA will be the same.
8464
Yes but they often dont with fertility issues and the knowledge they may not see their children grow.  ;) Childbirth and pregnancy can aggravate CF and kill the mother.
748000
yes, they could have.\n\nHowever, more likely they were both just carriers for a recessive gene.
903731
How, why, how long, any other abnormalities, any other family members abnormal, what age....???\n\nNo one can possibly comment or reasonably respond to your question when you give no information.  \n\nYou need to spend another 5 points and really give people something to go on if you expect a helpful answer.
30692
Yes, but there is an increased risk of their child also having Down Syndrome. Sometimes very mentally retarded people are sterile though, so if this is a question pertaining to a certian someone you know, they'd need to get a check up to find out for SURE.
664657
Probably not...some heart valve problems are hereditary, but if his was caused by the disease, chances are , in this case, it is not.
773406
I doubt you are going to devine an answer to such a complicated issue on this or any forum.  First of all no one can predict the future.  Secondly the child apparently hasn't yet been diagnosed completely.  Instead of fishing around for answers that no one can possibly provide, offer your complete support to the family both the parents and children there in.\nThese questions serve no good purpose and as I mentioned aren't going to yield palpable answers.
346303
Well, I imagine if you dad has "bad" genes to contribute and your mom has nothing to contribute to the matter...You'll have "bad" genes also.