What are the reason liver cells become abnormal?
154224
becoming an abnormal liver cell is just like the rest of the other cells inside the body. If there's any kinds of cell having an abnormal growth (either by size, colour & shape), not to mention having a great significant increase in amount,  that's because they had been induced by a carcinogenic factors. Carcinogenic factors are the factors which lead to cancer. An abnormal growth of cell could become worse if there's no early treatment of prevention.
876475
Liver failure.  Tylenol is now one of the leading causes of liver failure and liver transplants.
490845
the pancreas stops producing insulin which is necessary to get the sugar in the blood stream into the cells where it can be used.  Thus the liver starts to break down the bodies fat and do gluconeogenesis.
763720
You should do your homework on your own,,, Besides, I sat here for a few minutes and I could not figure it out.\n\ncirrhosis (of the liver)
157522
He should go and see a doctor.......could have an inflammation of the liver or something else. Might be /or not related.\nAlcohol abuse can cause loads of problems.
67498
Fibrosis usually results from inflammation.  Tissue that is damaged attracts immune cells to help repair the damage or fight the infection.  This can lead to inflammation.  Long term inflammation or chronic inflammation can lead to more permanent changes, including fibrosis.  Extensive fibrosis can lead to scarring.\n\nThis differs depending upon whether you are referring to fibrosis and scarring in the liver (as a result of viral hepatitis, alcohol or drug induced hepatitis, etc.) or other types of tissue injury or damage.
1055426
Hemachromatosis is a disorder of iron regulation – it is an inherited disease where excess "free" iron is deposited in various organs including the liver. It is 'free' because it is not bound tightly to carrier proteins which would otherwise prevent it from damaging cells.\n\nThe problem is that because of the chemical properties of iron, it cannot be broken down and eliminated from the body. Therefore this situation leads to iron overload in the body.
322961
It's called "jaundice", and it represents a buildup of toxins in the body which the liver no longer filters efficiently.
878124
No need to worry unnecessarily.  However, there are serious conditions that can relate to your liver.  For instance, "cirrhosis" is known as the "silent killer."  The liver deals with over 500 processes within your body, including how you absorb nutrients and excrete toxins.\n\nTo find out how your liver is doing, go to a real doctor and ask them to run some basic lab work, including liver enzymes and liver function.  Hopefully, all is well.  It is money well spent; whether to find out what is wrong, or to find out there is nothing to worry about.  \n\nIn the meantime, I will pray for a clean bill of health for you!\n\nPeace be with you!
1118098
Yeah as far as I know, a liver problem. Go to the doc!
70433
Bilirubin is a naturally occuring byproduct of the metabolism of hemoglobin, the compound in red blood cells that is responsible for transporting oxygen in the blood. Bilirubin metabolism begins with the breakdown of red blood cells. Red blood cells contain hemoglobin, which is broken down to heme and globin. Heme is converted to bilirubin, which is then carried by albumin in the blood to the liver.\nIn the liver, most of the bilirubin is excreted in the bile. When bilirubin levels are too high, an infant can develop jaundice, a yellowish discoloration of the skin that comes from too much bilirubin circulating in the blood. This can occur in healthy newborns. There are a number of causes of jaundice in the newborn, including the inability of the liver to metabolize bilirubin.\n\nTake a look at some of the links below. If you are very concerned talk to the infant's pediatrician.\n\nHope this helps.
130261
Liver disease can cause high ALT, but taken together with a high alkaline phosphatase level, it is more likely a cholestatic cause, e.g., something common like gallstones can cause it too.  However, wait for the results of the tests before you jump to any conclusions.
367726
Normal metabolism produces Ammonia within the body, which is toxic.  This Ammonia must be neutralized.  One of the ways the human body does this is the production of urea or uric acid in the liver.  Excess amino acids are also turned into Urea within the body.\n\nIf an excess of Uric acid occurs in the body ( Eating the wrong foods, kidney malfunction ), a condition called GOUT occurs...VERY painful joints and cartilage...
850862
A laboratory report of elevated liver enzymes is common. It doesn't indicate a specific disease. However, it may be due to a liver disorder, even if you don't have any symptoms of liver problems. To determine the underlying cause of elevated liver enzymes, your doctor may recommend further testing.\n\nLiver enzymes help maintain a variety of chemical and metabolic processes that occur in the liver. Normally, only very small amounts of these enzymes are present in your blood.\n\nCommon causes of elevated liver enzymes include:\n\nMedications, such as certain non steroidal anti-inflammatory drugs, cholesterol-lowering medications, antibiotics and anti-seizure medications \nDrinking too much alcohol \nObesity \nDiabetes \nElevated triglycerides \nInfection, such as viral hepatitis and mononucleosis \nAutoimmune disorders of the liver and bile ducts, such as autoimmune hepatitis and primary sclerosing cholangitis and primary biliary cirrhosis \nMetabolic liver disease, such as hemochromatosis and Wilson's disease \nExcessive use of certain herbal supplements, such as kava, comfrey, pennyroyal and skullcap \nTumors of the liver or bile ducts \nTreatment of elevated liver enzymes depends on the underlying cause. It is important to tell your doctor about any nutritional or herbal supplements you are taking.\n\nFor further info related to elevated enzymes and different diseases please go to the website below.
750716
bilirubin elevation is usually caused by jaundice & liver disease. In newborns it's treated by exposure to a "bili" light, in adults they need to see a specialist
310214
That's a rather broad question...  You would probably have to specify it a little more to get the answer you are looking for.  But that said, there are numerous reasons as to why animal cells may develop an "abnormal" morphology.  Basically, there are perhaps two categories that can roughly be differentiated, even though - again - you have to be careful there.  One would be genetic reasons, another would be environmental reasons.  Genetic causes could be numerous as well, but take certain cancers for example, that have a genetic predisposition.  Certain environmental toxins can likewise lead to malformation of cells.  Please note that I was talking of a genetic "predisposition".  Often in case of cancer ebnvironmental and genetic effects are both responsible for the adverse effects observed.  So, the two categories are not ontological absolutes.  \n\nPerhaps what would help you to envision the problem is the basics.  First, cells divide mitotically in unicellular organisms.  consequently, a central question would be the default state of the cell.  There are three possibilities: (a) quiescence (i.e., the cell does not divide and needs an initiation of the mitotic process), (b) proliferation (i.e., cells default state is division and it needs particular factors to asure quiesence as needed in many multicellular organs), and (c) neither, since cell division is contextual.  The most common assumption in biology (and cancer biology, for that matter) is (a).  (b) has been suggested by  Carlos Sonnenschein and Ana Soto ("The Society of Cells. Cancer and Control of Cell Proliferation." New York: Springer, 1999).  Personally, I tend towards (c).  \n\nSecond, cells that proliferate during organogenesis have to further differentiate into the morphology and functionality they are to have in a specific organ.  \n\nThird, certain organs have cells that proliferate, whereas other organs don't.  Consequently, once everything goes well intially in organs of the second type, malformation may not occur as easily.  However, that said there are of course cancers of organs that normally do not have proliferating cells.  \n\nThese three basics may help you to ask your question a little more specifically and then seek out the literature that could give you answers accordingly.\n\nFinally, just remember that what is considered normal in science is the mean of a population.  But what determines this mean is often unclear.  I am thinking here for example of norms of reaction where cells may be shaped quite differently in response to environmental factors, and yet function wonderfully - in fact just exactly as they should given the particular environment.  Now, what is "deformed" would have to be probably understood functionally (i.e., a morphology associated with a functional break down).  And it seems to me that this is what you are looking for anyway.\n\nHope this helps.
463698
HEPATIOC STEATOSIS (fATTY LIVER) following even moderate intake of alcohol, small (microvesicular) lipid droplets accumulate in hepatocytes. with chronic intake of alcohol. lipid accumulates to the point of creating large, clear "macrovesicular" globules, compressing and displacing the nucleus to the periphery of the hepatocyte. this transformation is initially centrilobular, but in severe cases may involve the entire lobule. Macroscopically the fatty liver of chronic alcoholism is large (upto 4-6kg), soft organ that is yellow and greasy. the fatty change is completely reversible if there is abstentation from further intake of alcohol.\nNON ALCOHOLIC LIVER DISEASE.\nIs a condition that resembles alcohol induced liver disease, but occurs in patients who are not heavy drinkers. men and women are equally affected, there are strong associations with obesity, dyslipidemia, hyperinsulinemia.\npatients are largely asymptomatic, with abnormalities only in biochemical laboratory tests.