how do i determine the minimum lethal dose of antibiotics against bacteria?
100001
First you have to determine the bacteria strain.
716418
Hi,\nI went to Lab Tests Online and could only find the following when searching for the word...resistance.\nInsulin Resistance\nHIV Genotypic Resistance Testing\nSusceptibility Testing (bacterial resistance)\n\nNot sure which one is the best fit, but I think it might be bacterial resistance. Bacteria are often resistance to antibiotics (and other drugs) for many reasons. Some bacteria are resistant because of properties of their cell wall, metabolism (meaning they can actually destroy the antibiotics if the ingest ("eat") them ), or by multiplying quickly they effectively dilute the antibiotic. Some bacteria can mutate, or change, so that a given antibiotic will be ineffective. The above article explains acquired resistance through a selection process. If a person doesn't take the full course of antibiotics (say only 3 days of a 7 day course), the stronger bacteria will survive, and the next generations of bacteria will also survive that same antibiotic.\nA resistance test assay, I believe, would involve testing the ability of two or more antibiotics in destroying a certain bacteria.\n(sorry I couldn't find anything on the Internet to back this belief up,\nI am doing my best to think back on a few biology classes).
848383
Not as of yet, the problem is that it has been mutating to quickly for an effective vaccine to be developed.  It is a virus, so it can't be killed with antibiotics.  It has to be prevented with vaccination and since it has shown a high mutation capacity it may be some time before anything is discovered to inhibit its mutation capabilities and then kill it.
1108763
It's to be certain that all the germs have been killed by the antibiotic.  If you stop the drug after a few days, the remaining germs can mutate and develop a resistance to the drug, and come back to make you sicker than you were before.
1073348
Some antibiotics you can take and have no effect. It just depends on what it is. If you're worried, call your doctor or even your pharmacist and ask them.
792062
1) Collect your microbial agent\n2) Inoculate it into enriched media\n3) Place 3 mm size ring of ointment onto the agar\n4) Check in 24 hours and measure the inhibition zone
658448
Making sure the full course of antibiotics is taken to make sure  all bacteria are killed and none are left to build up resistance. Using a combination of antibiotics is also needed./
50014
Some bacteria cells are naturally more or less resistant to bacteria - it's genetic variation just like some people are more resistant to the effects of alcohol.  When a population of bacteria is exposed to an antibiotic, some will die right away, while more naturally resistant bacteria will stay alive.  If there is not enough antibiotic to kill all the bacteria (like if someone doesn't take all the antibiotics prescribed to them), only the bacteria that were naturally more resistant will be left.  With little competition to keep them from replicating (because all those less resistant bacteria died), the remaining cells will reproduce to form an entire population of resistant bacteria.
600976
FDA recommends a critical\nlimit of 40 ‘F or less. Histamine and/or toxin formation (produced.by\nmicrobial growth) are hazards that can result from exposure to temperatures\nabove 40 ‘F for extended periods of time.
443297
Not much, actually-You dont want something that kills the bacteria in the mouth, because they are the primary protection against even worse things.  People who have to take very high doses of antibiotics often loss the bacteria in the mouth, and then have things like thrush, yeast, even massive fungal infections-and these are extremely hard to treat.  Toothpaste just scrapes the bacteria off the tooth, so the acidic waste products of the bacteria dont eat away the enamel.
490824
hi my name is Geeth Prajwal from India i hope this will help you\n\n\n\nIn order to be useful in treating human infections, antibiotics must selectively target bacteria for eradication and not the cells of its human host. Indeed, modern antibiotics act either on processes that are unique to bacteria--such as the synthesis of cell walls or folic acid--or on bacterium-specific targets within processes that are common to both bacterium and human cells, including protein or DNA replication. Following are some examples. \n\nMost bacteria produce a cell wall that is composed partly of a macromolecule called peptidoglycan, itself made up of amino sugars and short peptides. Human cells do not make or need peptidoglycan. Penicillin, one of the first antibiotics to be used widely, prevents the final cross-linking step, or transpeptidation, in assembly of this macromolecule. The result is a very fragile cell wall that bursts, killing the bacterium. No harm comes to the human host because penicillin does not inhibit any biochemical process that goes on within us. \n\nBacteria can also be selectively eradicated by targeting their metabolic pathways. Sulfonamides, such as sulfamethoxazole, are similar in structure to para-aminobenzoic acid, a compound critical for synthesis of folic acid. All cells require folic acid and it can diffuse easily into human cells. But the vitamin cannot enter bacterial cells and thus bacteria must make their own. The sulfa drugs such as sulfonamides inhibit a critical enzyme--dihydropteroate synthase--in this process. Once the process is stopped, the bacteria can no longer grow. \n\nAnother kind of antibiotic--tetracycline--also inhibits bacterial growth by stopping protein synthesis. Both bacteria and humans carry out protein synthesis on structures called ribosomes. Tetracycline can cross the membranes of bacteria and accumulate in high concentrations in the cytoplasm. Tetracycline then binds to a single site on the ribosome--the 30S (smaller) ribosomal subunit--and blocks a key RNA interaction, which shuts off the lengthening protein chain. In human cells, however, tetracycline does not accumulate in sufficient concentrations to stop protein synthesis. \n\nSimilarly, DNA replication must occur in both bacteria and human cells. The process is sufficiently different in each that antibiotics such as ciprofloxacin--a fluoroquinolone notable for its activity against the anthrax bacillus--can specifically target an enzyme called DNA gyrase in bacteria. This enzyme relaxes tightly wound chromosomal DNA, thereby allowing DNA replication to proceed. But this antibiotic does not affect the DNA gyrases of humans and thus, again, bacteria die while the host remains unharmed. \n\nMany other compounds can kill both bacterial and human cells. It is the selective action of antibiotics against bacteria that make them useful in the treatment of infections while at the same time allowing the host to live another day.
867934
Its an antibiotic.. look it up on a search engine.
1083576
Bacteria dies with anti-biotics
1043317
Antibiotics literally translates to "destroy-life".  Antibiotics are designed to remedy bacterial infection, by killing the living bacteria that causes the infection.\n\nYour doctor most likely said that you have a VIRAL infection.  This means that it is from a virus.  Viruses are not living things in the same way that bacteria are, so they cannot be killed by antibiotics.  Instead, they have to run their course as your body fights them off.\n\nTo the best of my knowledge, there is no such thing as a VITAL infection, you may have just misheard or miskeyed.
84488
This deals with antibiotic susceptibility testing on (usually Mueller-Hinton) agar plates.  \nFirst you coat the surface of the plate with a bacterial suspension, then you place a disc with whatever antibiotic you're using on the surface of the plate.  After you incubate the plate for about 18 to 24 hours, you will see a zone of inhibition around the disc if the bacteria are killed, or inhibited, by the antibiotic.  This is an area of no bacterial growth.  The sizes of the zones vary depending on the concentration of the antibiotic in the disc, the depth of the agar, the susceptibility of the bacteria, and the concentration of the origional bacterial suspension, etc. . .\n\nHope this helps!
451445
No it will kill only certain bacteria.You have to do a culture+ABST test to find out what antibiotic is sensitive for what.ABST stands for antibiotic sensitivity test.Do not rake your brain, we are raking our brain for you.\n\nDr K.S.A.Kumarasiri(MD)
800007
there are things like flash drives, antimicrobial susceptibility testing kits by this name on te internet, you want to be a little more specific next time you ask this question, good luck