what is cutaneous T-cell lymphoma?
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CTCL is a rare type, making up about 5% of all cases. It is a cancer of the T-lymphocytes and most often occurs in people aged between 40 and 60.\n\nUnlike other forms of non-Hodgkin’s lymphoma, CTCL mainly affects the skin. It is caused by the uncontrolled growth of a type of white blood cell within the skin, called a T-cell. \n\nThe most common types of CTCL are mycosis fungoides or Sezary syndrome. Sezary syndrome is a specific type of CTCL in which large areas of skin or lymph glands are affected and abnormal T-lymphocytes are also found in the blood. Mycosis fungoides is the general name given to the other types of CTCL when the blood is not affected.
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Here are some excellent sites:\nDr Weems dermatopathology site: http://www.bweems.com\nDr Roy's sites: http://www.histopathology-india.net/dermpath.htm\nhttp://www.histopathology-india.net/SoftTissuePath.htm
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It could be a lot of things, with the worst being a skin cancer. He needs to go to his doctor or a dermatologist to be checked. Some of the skin cancers can actually spread and become fatal. Tell him you love him and want him to be around for a long time, then hand him the appointment card....
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you should see a dermatologist
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Okay, this is a kid's site, but it was (not joking) the most informative I could find. \nhttp://kidshealth.org/kid/health_problems/skin/fungus.html\n\nThis site is very informative as well:\nhttp://www.lymphedemapeople.com/thesite/lymphedema_skin_fungus.htm\n\nFrom my Mycology (study of fungi) notes:\nTiniea capitis affects the scalp\nTinea barbae affect the beard\nTinea corporis affects the entire body\nTinea cruris is the cause of jock itch\nTinea pedis would be athletes foot\nTinea unguium affect the hair\n\nThese are all dermatophytes and there are three genera: microsporum, epidermaphyton, and trichophyton.\n\nOther superficial fungal infections are Mallassizia furfur that causes white patches on the skin, P. wernecki (commonly known as Tinea nigra) that cause ring worm, and Piedra hortae and Trichosporon biegelii that affect the hair.\n\nI hope I didn't overwhelm you with information and that it is helpful. I can get you more information if you need it. There are several more types of fungi. These only affect the first layer of skin and hair. Others are more invasive. Hope that helps.
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90% of the time, itchy skin is merely a sensitivity to something in your environment--it's the other 10% that you'll need to be concerned about.  Itchy skin can be a symptom of certain cancers, such as Hodgkin's Disease Lymphoma.  I ask you, are there other symptoms such as unexplained weight loss, night sweats (drenching amounts of sweat that only occur while sleeping), or fatigue?  Even if there isn't, I'd still recommend seeing a doctor, who can use some simple blood tests to determine whether it's worth further examining.\n\nYou may also be experiencing allergies to something such as detergents (I doubt this one, or you'd be itching everywhere clothing touches you), dust, soaps, shaving creams or gels, or even certain foods.  Think back to when this all started, and see if you can remember any changes you made out of the ordinary.  You may also try changing your razor if you shave your legs; sometimes the blades of mass-produced razor heads aren't in exact allignment, and the tiny little scrapes that they produce--even if you didn't feel them when they happened--can become irritated and make your skin itch.  In fact, the little bumpy rashes you described fit nicely with this possibly being the problem.\n\nFor relief in the meantime, you can try taking Benadryl tablets along with using Hydrocortisone creams.  You're right to be aware of how much you're scratching, since it's easy to make a bad situation even worse by creating little open wounds with your fingernails.\n\nWhatever you do, please go to a doctor first and work this issue from worse-case scenero first before switching over this and that, these and those.  \n\nGood luck to you!
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Non-Hodgkin's lymphoma (NHL) is cancer of the cells of the lymphatic system. In non-Hodgkin's lymphoma, cells in the lymphatic system divide and grow without order or control, or old cells do not die as cells normally do. Non-Hodgkin's lymphoma can start almost anywhere in the body. It may occur in a single lymph node, in a group of lymph nodes, or in an organ such as the spleen. Non-Hodgkin's lymphoma can spread to almost any part of the body, including the liver, bone marrow, and spleen.\n\nOver time, lymphoma cells replace the normal cells in the bone marrow. This causes bleeding problems and infections. As the lymphoma cells spread, the body becomes less and less able to produce blood cells that carry oxygen to other tissues or to protect itself from infection.\n\nThe cause of non-Hodgkin's lymphoma is unknown. The incidence of NHL has continued to increase over the years. It is probably a genetic disorder and may require a "trigger," such as exposure to something in the environment, to develop. NHL is not contagious.\n\nNHL is more common in men than in women. \n\nThe likelihood of getting NHL increases as you get older. \nNHL is most common among those who have an inherited immune deficiency, an autoimmune disease, or HIV; it also occurs among those who take medications that impair the immune system following an organ transplant. \n\nViral infections, such as with human T-lymphotropic virus type I (HTLV-1) and Epstein-Barr virus, increases the risk of developing NHL. \n\nExposure to pesticides, solvents, or fertilizers increases the risk of developing NHL. \n\nThe most common symptom of non-Hodgkin's lymphoma is a painless swelling of the lymph nodes in the neck, underarm, or groin. Other symptoms may include:\n\nUnexplained fever. \nNight sweats. \nExtreme fatigue. \nUnexplained weight loss. \nItchy skin. \nReddened patches on the skin.\nNon-Hodgkin's lymphoma is different from Hodgkin's lymphoma and occurs about eight times more often.\n\nOn the other hand, Hodgkin's lymphoma is cancer of the lymph system, which is the network that carries lymph fluid, nutrients, and waste material between the body tissues and the bloodstream to help protect a person against disease. \n\nSymptoms of Hodgkin's lymphoma include enlargement of the lymph nodes, fever, appetite loss, weight loss, and night sweats.\n\nHodgkin's lymphoma affects men more often than women. The cause of Hodgkin's lymphoma is not known.\n\nTreatment for Hodgkin's lymphoma depends on the stage of the lymphoma and may include radiation or chemotherapy.
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You need to speak to your dermatologist about it.  There are treatments, it's just a matter or trying them and finding one to help.
922615
Skin cancer is a malignant growth on the skin, which can have many causes, including repeated severe sunburn or long-term exposure to the sun. Skin cancer generally develops in the epidermis, the outermost layer of skin, so a tumor is usually clearly visible. This makes most skin cancers detectable in the early stages. There are three common types of skin cancer each of which are named after the type of skin cell.\n\nThe most common types are \nbasal cell carcinoma (BCC) and \nsquamous cell carcinoma (SCC) \nwhich may be locally disfiguring but unlikely to spread to other parts of the body. \nThe most dangerous type is malignant melanoma, which can be fatal if not treated early, but forms only a small proportion of all skin cancers.\n\nOther types of skin cancer are:\n\nDermatofibrosarcoma protuberans \nMerkel cell carcinoma \nKaposi's sarcoma \n\nFor more Details about skin cancer Prevention, Genetics, Causes, Treatment, Screening and Testing, Cancer Literature, Research and Related Information, Statistics.\nhttp://www.cancer.gov/cancertopics/types/melanoma
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http://www.emedicine.com/DERM/topic691.htm\nhttp://www.ninds.nih.gov/disorders/a_t/a-t.htm\nhttp://www.ncbi.nlm.nih.gov/disease/ATM.html\nhttp://www.atsociety.org.uk/\n                                                                                              bye :)
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arthritis\n\nI'm posititve\nKaposi's sarcoma is a cancer that causes purple lesions on the skin--most often in men with AIDS\nTuberculosis, pneumonia, and yeast infections are known as opportunistic infections--infections that healthy individuals can usually fight off, but those who are immuno-compromised have a difficult time fighting these infections.
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Skin Cancer\n\nThe skin is the largest organ in our body. It provides protection against heat, cold, light, and infection. The skin is made up of two major layers (epidermis and dermis) as well as various types of cells. The top (or outer) layer of the skin—the epidermis—is composed of three types of cells: flat, scaly cells on the surface called squamous cells; round cells called basal cells; and melanocytes, cells that provide skin its color and protect against skin damage. The inner layer of the skin—the dermis—is the layer that contains the nerves, blood vessels, and sweat glands. \n\nWhat Is Skin Cancer?\nkin cancer is a disease in which cancer (malignant) cells are found in the outer layers of your skin. There are several types of cancer that originate in the skin. The most common types are basal cell carcinoma (70 percent of all skin cancers) and squamous cell carcinoma (20 percent). These types are classified as nonmelanoma skin cancer. Melanoma (five percent of all skin cancers) is the third type of skin cancer. It is less common than basal cell or squamous cell skin cancer, but potentially much more serious. Other types of skin cancer are rare.\n\n\nBasal Cell Carcinoma is the most common type of skin cancer. It typically appears as a small raised bump that has a pearly appearance. It is most commonly seen on areas of the skin that have received excessive sun exposure. These cancers may spread to the skin around the cancer but rarely spread to other parts of the body.\n\nSquamous Cell Carcinoma is also seen on the areas of the body that have been exposed to excessive sun (nose, lower lip, hands, and forehead). Often this cancer appears as a firm red bump or ulceration of the skin that does not heal. Squamous cell carcinomas can spread to lymph nodes in the area.\n\nMelanoma is a skin cancer (malignancy) that arises from the melanocytes in the skin. These cancers typically arise as pigmented (colored) lesions in the skin with an irregular shape, irregular border, and multiple colors. It is the most harmful of all the skin cancers, because it can spread to other sites in the body. Fortunately, most melanomas have a very high cure rate when identified and treated early.\n\nWho Gets Skin Cancer?\n\nSkin cancer is a disease that has shown a steady increase over the past 20 years. Fortunately, with early diagnosis and treatment, it remains a very curable disease. A variety of factors have been identified that place a person at a higher risk to develop skin cancer (see “Am I at risk?”).\n\nHow Is Skin Cancer Diagnosed?\n\nThe vast majority of skin cancers can be cured if diagnosed and treated early. Aside from protecting your skin from sun damage, it is important to recognize the early signs of skin cancer.\n\n    * Skin sores that do not heal,\n    * Bumps or nodules in the skin that are enlarging, and\n    * Changes in existing moles (size, texture, color). \n\nIf you notice any of the factors listed above see your doctor right away. If you have a spot or lump on your skin, your doctor may remove the growth and examine the tissue under the microscope. This is called a biopsy. A biopsy can usually be done in the doctor's office and usually involves numbing the skin with a local anesthetic. Examination of the biopsy under the microscope will tell the doctor if the skin lesion is a cancer (malignancy).\n\nHow Is Skin Cancer Treated?\n\nThere are varieties of treatments available, including surgery, radiation therapy, and chemotherapy, to treat skin cancer. Treatment for skin cancer depends on the type and size of cancer, your age, and your overall health.\n\nSurgery is the most common form of treatment. It generally consists of an office or outpatient procedure to remove the lesion and check edges to make sure all the cancer was removed. In many cases, the site is then repaired with simple stitches. In larger skin cancers, your doctor may take some skin from another body site to cover the wound and promote he
1132739
that means your lymphoma has spread to more than one location.
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I wouldn't waste anytime getting to the doctor for a diagnosis and a referral to a skin specialist. I had a skin condition that was misdiagnosed as a form of Shingles for 2yrs. As it turned out we have now found out its a form of Lupus that effects the skin called Discoid Lupus. They don't know what causes this but it is worsened and sometimes kick started in the 40 plus age group by direct sunlight and Heat. There are many things it could be but best to rule out all the nasties as soon as possible. Good Luck.
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http://www.mayoclinic.com/health/dermatographia/HQ00528\n\nnot saying that you have this, but it is a possibility? see dermatologist if concerned, does not seem sinister from what i hear.....
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Hodgkin's disease, sometimes called Hodgkin's lymphoma, is a cancer that starts in lymphatic tissue. Lymphatic tissue includes the lymph nodes and related organs that are part of the body's immune and blood-forming systems. The lymph nodes are small, bean-shaped organs found underneath the skin in the neck, underarm, and groin. They are also found in many other places in the body such as inside the chest, abdomen, and pelvis. \n\nLymph nodes make and store infection-fighting white blood cells, called lymphocytes. They are connected throughout the body by lymph vessels (narrow tubes similar to blood vessels). These lymph vessels carry a colorless, watery fluid (lymphatic fluid) that contains lymphocytes. Eventually the lymphatic fluid is emptied into the blood vessels in the left upper chest. \n\nOther components of the lymphatic system include the spleen, the bone marrow, and the thymus. The spleen is an organ in the left side of the upper abdomen that is composed primarily of mature and immature lymphocytes. It removes old cells and other debris from the blood. The bone marrow is the spongy tissue inside the bones that creates new red and white blood cells including lymphocytes. The thymus is a small organ in the chest that is important in developing a special lymphocyte called a T cell. \n\nBecause lymphatic tissue is present in many parts of the body, Hodgkin's disease can start almost anywhere, but most often starts in lymph nodes in the upper part of the body. The most common sites are in the chest, neck, or under the arms. Hodgkin's disease enlarges the lymphatic tissue, which can then cause pressure on important structures. It can spread through the lymphatic vessels to other lymph nodes. This is the major way it spreads. Most Hodgkin's disease spreads to nearby lymph node sites in the body, not distant ones. It rarely gets into the blood vessels and can spread to almost any other site in the body, including the liver and lungs. \n\nLymph nodes enlarge for many reasaons. Although Hodgkin's disease is one cause, enlarged lymph nodes are more commonly a result of the body fighting an infection. Your doctor can help determine the cause. \n\nHodgkin's disease is a malignant lymphoma (cancer of lymphatic tissue). There are two kinds of lymphomas: Hodgkin's disease (named after Dr. Thomas Hodgkin who first recognized it in 1832) and non-Hodgkin's lymphomas. For information on non-Hodgkin's lymphomas see the document "Non-Hodgkin's Lymphomas". \n\nThe cancer cells in Hodgkin's disease are called Reed-Sternberg cells, after the two doctors who first described them in detail. Under a microscope they look different from cells of non-Hodgkin's lymphomas and other cancers. Most scientists now believe that Reed-Sternberg cells are a type of malignant B lymphocyte. Normal B lymphocytes are the cells that make antibodies that help fight infections. \n\nDoctors have given names to different types and subtypes of Hodgkin's disease. The two main types are classical Hodgkin's disease (which has several subtypes) and nodular predominant Hodgkin's disease. \n\n\nClassical Hodgkin's disease:\n\n\nLymphocyte predominance \nNodular sclerosis \nMixed cellularity \nLymphocyte depletion \nUnclassified. \nNodular lymphocyte predominant Hodgkin's disease\n\n\nAll of these types are malignant because as they grow, they may compress, invade, destroy normal tissue and spread to other tissues. There is no benign (noncancerous) form of Hodgkin's disease
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Here you go!\n\nhttp://dermatology.cdlib.org/114/NYU/NYUtexts/1116045.html\n\nhttp://www.thedrsdr.com/diseases/necrobiotic_xanthogranuloma.htm\n\nhttp://archderm.ama-assn.org/cgi/content/abstract/128/1/94\n\nhttp://www.histopathology-india.net/NX.htm\n\nhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12064218&dopt=Abstract\n\nBest answer?