Anyone have any information on which receptors THC effects? Opiate receptors?
105759
"In the brain, THC connects to specific sites called cannabinoid receptors on nerve cells and influences the activity of those cells. Some brain areas have many cannabinoid receptors; others have few or none. Many cannabinoid receptors are found in the parts of the brain that influence pleasure, memory, thought, concentration, sensory and time perception, and coordinated movement"
230999
As somebody who has used cannabis regularly for too many years I can say yes, it is possible to see trails and auras when very stoned but I have never experienced anything that lasts past the next morning.  I have never head of any long term damage being done but cannabis does have an effect on the intra-ocular pressure (the pressure of fluid in the eye) hence it being used, illegally, in the treatment of the eye condition glaucoma. \n\nI wouldn’t imagine a mother’s ingestion of LSD would effect her eggs as a woman’s eggs are already made at the time of her birth, unlike sperm which are made daily.  If she took it while pregnant there could be an effect though I suppose, depending on how readily the drug crosses the placenta.\n\nDifferent peoples reactions to cannabis vary quite greatly and people who are highly sensitive can experience a trippier experience.  It obviously also depends on the type and quality of the weed.\n\nI have heard  people experiencing ‘ego loss’ from LSD but not from cannabis.\n\nCheck out www.erowid.com for lots of unbiased drug information and other peoples experiences, you may find some similar souls!
39174
Opiates root down in your hair follicles for several months, but its out of your urine in less than a week. Dont be curious about doing it if you havent, though. Trust me. IF your talking the length of the 'high', that depends how you use it. smoking it gives a good high, but lasts the least longest. Snorting it lasts a couple hours, and the afterglow is for a few more, and once you graduate to shooting it, you realize that snorting and smoking it is a complete waste of time, energy and heroin, and it lasts the longest. The most bang for your buck, so to speak. Also is the most dangerous, obviously. Once you go over this bridge however, there is no going back. Ever.
165795
http://www.erowid.org/plants/cannabis/cannabis_testing.shtml
13141
go to www.erowid.com. It will help with any questions you have at all about any drug you can think of, and is just pretty cool on top of that.
74782
Long-term physical effects of smoking marijuana;\nIn some ways, the effects of smoking cannabis are similar to the effects of smoking any substance. Any time you inhale smoke, the respiratory system is adversely affected. These effects are particularly apparent with repeated and prolonged use. Studies have pointed out that cannabis produces more tar and burns at a higher temperature than tobacco. Some cannabis smokers inhale the smoke more deeply and hold it in their lungs for a longer period of time. However, the average cannabis user smokes less frequently, and there is evidence that cannabinoids present in cannabis may actually serve to protect against cancer. http://ehp.niehs.nih.gov/docs/2000/108-10/correspondence.html#thc Furthermore, the concentration of toxic and carcinogenic additives such as nicotine, arsenic, and radium-226, is substantially greater in tobacco cigarettes than in cannabis.Medically, cannabis is most often used as an appetite stimulant and pain reliever for certain terminal illnesses such as cancer and AIDS. It is also used to relieve glaucoma and certain neurological illnesses such as epilepsy ,migraine and bipolar disorder. The medical use of cannabis is politically controversial, but it is sometimes recommended informally by physicians. A synthetic version of the active ingredient in cannabis, THC, is readily available in the form of a pill as the prescription drug Marinol. THC has also been found to reduce arterial blockages.http://www.nature.com/news/2005/050404/full/050404-7.html A sublingual spray derived from an extract of cannabis has also been approved for treatment of multiple sclerosis in Canada as the prescription drug Sativex.
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"Animal research has shown that the potential for cannabinoid psychological dependence does exist, and includes mild withdrawal symptoms. Although not as severe as that for alcohol, heroin, or cocaine dependence, marijuana withdrawal is usually characterized by insomnia, restlessness, loss of appetite, irritability, anger, increased muscle activity (jerkiness), and aggression after sudden cessation of chronic use as a result of physiological tolerance. Prolonged marijuana use produces both pharmacokinetic changes (how the drug is absorbed, distributed, metabolized, and excreted) and pharmacodynamic changes (how the drug interacts with target cells) to the body. These changes require the user to consume higher doses of the drug to achieve a common desirable effect, and reinforce the body’s metabolic systems for synthesizing and eliminating the drug more efficiently.\n\nPreliminary research, published in the April 2006 issue of the Journal of Consulting and Clinical Psychology, indicates that cannabis addiction can be offset by a combination of cognitive-behavioral therapy and motivational incentives. Participants in the study (previously diagnosed with marijuana dependence) received either vouchers as incentives to stay drug free, cognitive-behavioral therapy, or both over a 14-week period. At the end of 3 months, 43 percent of those who received both treatments were no longer using marijuana, compared with 40 percent of the voucher group, and 30 percent of the therapy group. At the end of a 12-month follow-up, 37 percent of those who got both treatments remained abstinent, compared with 17 percent of the voucher group, and 23 percent of the therapy group."\n\nThis, and more, available on the free, online encyclopedia, Wikipedia at:\nhttp://en.wikipedia.org/wiki/Health_issues_and_the_effects_of_cannabis\n\nThe National Institutes of Health (NIH) has a report entitled, "Combination of Cognitive-Behavioral Therapy and Motivational Incentives Enhance Treatment for Marijuana Addiction" at this web site:\nhttp://www.nih.gov/news/pr/apr2006/nida-01.htm\n\nHope this helps!
512599
I did a little research on-line and it looks like studies show that long-term opioid (i.e.,morphine) use can lead to irregular menses (periods). See your Dr. for more info.
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How Marijuana Smoking Affects the Body \n\nAdversely affects normal cell formation. \nProduces feelings of isolation and depersonalization. \nProduces shakes, lack of coordination and headaches. \nMakes any mental or emotional problem worse. \nIncreases the heart rate. \nHas 50 percent more tar per ounce than tobacco. \nDecreases air flow and creates loss of lung capacity in little more than a month of regular smoking. \nProduces chronic irritation of nasal and lung passages. \nCreates precancerous changes in the lungs of smokers in their 20s. \nSuppresses sex drive and sexual performance with prolonged use. \nCan lead to impotence. \nHarms the developing fetus. \nIs associated with increased still births, neonatal deaths, decreased birth weight and abnormal reactions in children born to mothers on marijuana. \nDecreases brain response, affects thinking and brain function, creates confusion and problems with short and long term memory, and distorts perception of time. \nCauses blackouts. \nImpairs driving skills. Studies show brake response time is increased, concentration is decreased and risk taking is increased. \nDistorts peripheral vision, especially in the first two hours after using. \nPeople who smoke marijuana generally have reduced energy, reduced motivation and decreased drive. Marijuana twists the mind with false moods, chemically induced distortions and unreal perceptions of people and life. Marijuana distorts what is stored in the memory. It lies to the user.\n\nSmoking marijuana decreases the chance for a naturally satisfying life. It is an especially harmful drug for young people. Just when teens and young adults are searching for motivation and the best way to achieve their dreams, marijuana robs them of motivation. Young people do less, learn less and become less capable when they smoke marijuana.\n\nSmoking marijuana drains self-confidence and arrests the development of confidence in a person's own ability to get natural rewards out of life. Because marijuana introduces people to altered perceptions and feelings, and an "I don't care" attitude, the drug encourages use of other drugs and sinks its users into an ever-deepening dependence on drug lifestyles. Drawn into the illegal drug culture, users are then available to those who are pushing other drugs.
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I doubt it. I'm on medications that will cause prelim drug screens to show pos... Pain medication I take comes back positive for opioid - and meds for Narcolepsy will cause pos for amphetamines   - so without another more specific test... it could appear I'm on speed and heroine LOL ~ the test is just A SCREEN, testing for like 4-6 "families"  it's extremely expensive to test for each individual drug. \n\nPoppy seeds can make em pop for opiates also - as Poppy's are what heroine is made from and codeine (I believe) BUT you'd have to eat an awful lot of muffins to get pos test:).\n\nThe reason my med's show pos on a test is because that's what they are, in some way - just like Poppy seeds, there is some form of these things in them... just legal, medically nec, and Dr. prescribed forms.\nBUT because I have a Dr. working with me and helping me... even though I do have to take these meds daily - they allow me to function regularly, do not effect my ability to preform - they actually make me able TO BE a good employee.\n\nAll that said... I believe THC is it's own family... I don't think it's in any other "med" - there are THC pills for cancer. Medical Marijuana... but I've never heard of anything that will make you show positive for pot that isn't pot. However, I'm no Dr. and certainly not an expert in this field - these are my own experiences.\n\nWhile it's probably illegal to ask him what he has - etc. it shouldn't be a problem to ask him to produce his prescription for the med he believes is causing the "false pos" or legal pos. \nThen call the lab that did the test and ask if that med in that dosage can cause a pos reading for THC... \nIF THEY SAY YES, then - I don't know if you'd need a med release or not to call the pharmacy & Dr. to verify that he is indeed taking this medication. Or ask for a letter from his Dr. YOU CAN CALL and ask the Dr. if he wrote you a letter for "so and so" \nIF he wants the job he should have no problem with helping you to understand his situation - so that you know he is a trustworthy responsible citizen with a health condition he is trying to manage and live with and not just someone who's judgement is clouded by a drug induced haze.
154748
http://www.jimmyr.com/endorphins.php
1029897
http://search.yahoo.com/search?p=%22long+term+effects+of+marijuana%22&ei=UTF-8&fr=ks-ques&x=wrt
652458
yeah, GOOD LUCK TO HIM... only drink a lot of water and do push ups because THC is stored in your fat and then if you do push ups, then you sweat it out. Always have a water bottle by you and it's gonna be all good.
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Below, I have provided a link that will give you information on marijuana's effect on driving, on the heart, lungs, psychological aspects of marijuana use, etc.  I would've copied and pasted the WHOLE thing, but it's quite extensive.
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THC (Tetrahydrocannabinol) can stay in a person's body for as long as 3 to 90 days after smoking or being ingested orally.\nThere are numerous determining factors for how long drug toxins stay in a persons body which vary from person to person, such as the analytical\nmethod used, your health, your body weight, metabolism, fluid intake, the type of drug toxin, and the degree of exposure to the drug toxin.\n\nDelta-9-Tetrahydrocannabinol or THC, one of nearly 400 chemicals in a cannabis plant, accounts for most of marijuana's psychoactive, or mind-altering, effects. The strength of the drug is determined by the amount of THC it contains which varies from plant to plant. Marijuana stays in your system for different amounts of time depending on how often you smoke it, how much you smoke, and the makeup of the individual (weight/height/etc.).
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The active ingredient of marijuana (terahydrocannabinol-THC) is a fat-soluble molecule whose metabolites may remain in the body for s long as a month after a single exposure. THC metabolites are stored in the brain, testes, ovaries, and other fatty tissues. With even so-called "mild use" of marijuana smoking once or twice a week, THC will be continually present in the body and slowly released, affecting overall functioning to some degree. This is true whether or not the individual experiences being "high." Despite statements to the contrary, marijuana users, especially with more frequent use, do develop physiological tolerance to the drug which necessitates higher "doses" to achieve the same subjective experience of intoxication. So over time, without necessarily a concurrent increase in intensity or frequency of the sensation of intoxication, increasing levels of active substance will be stored in the body and trying to get a quicker release of the stored substance in your body is of no avail except don't smoke it (especially if your job or schooling prohibits it). Any statements that refer to 'passing the test' got lucky, as all test have a % chance of a false reading...    You will just be taking a chance Good Luck
211107
Dude, what is up with all us 20 year olds getting arthritis!?!  I am in my 20s and I too have chronic osteoarthritis in my neck, upper back, hands, and knees.  I use marijuana as a pain reliever because it doesn't incapacitate me as much as something like morphine or vicoden, and also because I can grow it at home.  \n\nMarijuana helps with the pain, but it doesn't do anything to address the root problem of the arthritis, although I am not sure there is much out there that can, except for certain types of surgeries and some people say that Pregnazone helps reduce the advancement of arthritis in the body.  Pretty much all of us youngens who have arthritis early just need to get used to the pain...  :0(  I wish i had a better answer.