is ssri safe to take?
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SSRIs are generally safe for most people. However, in some circumstances they can cause problems. For example, high doses of citalopram may cause dangerous abnormal heart rhythms, so doses over 40 milligrams (mg) a day should be avoided according to the FDA and the manufacturer.
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There is new reason to be cautious about using popular antidepressants in people who are not really depressed. For the first time, research has shown that a widely used antidepressant may cause subtle changes in brain structure and function when taken by those who are not depressed. The drug is sertraline.
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There was a decreased risk of breast cancer associated with use of paroxetine hydrochloride and potentially fluoxetine. There is also evidence that antidepressant users who were not overweight had a decreased risk of breast cancer. Most studies have detected relative risks ranging from 0.7–1.3 for ever use of SSRIs.
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You can take escitalopram at any time of day, as long as you stick to the same time every day. If you have trouble sleeping, it's best to take it in the morning.
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Potential complications include maternal weight changes and premature birth. Most studies show that SSRIs aren't associated with birth defects. However, paroxetine (Paxil) might be associated with a small increased risk of a fetal heart defect and is generally discouraged during pregnancy.
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When citalopram is not utilized based on risk factors for TdP, use of escitalopram is not likely the safest alternative. Based on current literature, fluoxetine, fluvoxamine, and sertraline appear to have similar, low risk for QT prolongation, and paroxetine appears to have the lowest risk.
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Fluoxetine is the first line SSRI (licensed ≥ 8 years), NICE reports fluoxetine as the 'only antidepressant for which trials show the benefit outweighs the risks'.
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Taking sertraline for more than a year has also been linked to a small increased risk of getting diabetes. You'll be regularly checked for this. Otherwise there don't seem to be any lasting harmful effects from taking sertraline for many months and years. Is sertraline better than other antidepressants?
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More than 100 million people worldwide take selective serotonin reuptake inhibitors (SSRIs), such as Prozac and Zoloft, to treat depression, anxiety and related conditions, but these drugs have a common and mysterious side effect: they can worsen anxiety in the first few weeks of use, which leads many patients to stop ...
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Doctors often start by prescribing an SSRI. These drugs are considered safer and generally cause fewer bothersome side effects than other types of antidepressants. SSRIs include citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil, Pexeva), sertraline (Zoloft) and vilazodone (Viibryd).
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SSRIs include fluoxetine (Prozac), paroxetine (Paxil, Pexeva), sertraline (Zoloft), citalopram (Celexa) and escitalopram (Lexapro). Serotonin and norepinephrine reuptake inhibitors (SNRIs).
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Certain selective serotonin reuptake inhibitors (SSRIs). SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft). Potential complications include maternal weight changes and premature birth. Most studies show that SSRIs aren't associated with birth defects.
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SSRIs considered to have the best safety profile in the elderly are citalopram, escitalopram, and sertraline. [16] These have the lowest potential for drug-drug interactions based on their cytochrome P-450 interactions.
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SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft). Potential complications include maternal weight changes and premature birth. Most studies show that SSRIs aren't associated with birth defects.
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In people with bipolar disorder, SSRIs and other antidepressants carry a risk of inducing mania, making it essential to monitor for signs of excess energy, decreased need for sleep, or abnormal and excessive mood elevation.
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As with SSRIs, some of the side effects (such as feeling sick, an upset stomach, problems sleeping and feeling agitated or more anxious) are more common in the first 1 or 2 weeks of treatment, but these usually settle as your body adjusts to the medication.
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There has been little systematic long-term data regarding weight effects of SSRI antidepressants (which include fluoxetine (Prozac), sertraline (Zoloft), citalopram (Celexa), escitalopram (Lexapro), paroxetine (Paxil), and fluvoxamine (Luvox), and the SNRIs venlafaxine (Effexor) and duloxetine (Cymbalta), although some ...