what is dysplastic junctional melanocytic nevus?
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Junctional nevi are the result of a single abnormal melanocyte that begins to proliferate at the dermal epidermal junction, and are often seen clinically as a dark flat nevus. A junctional nevus will typically evolve over time into a compound nevus, which is a nevus with both epidermal and dermal melanocytes.
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Actinic keratosis is the name for small, scaly red or brown papules that are the result of excessive sun exposure. They are more common in people with fair skin, blonde or red hair, and blue or green eyes. They may progress to a type of skin cancer called squamous cell carcinoma.
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The term dyscrasia has been used in dermatology since 1978 when Gisser and Young introduced it as a heading for neoplastic disease of T cells in a patient with “pityriasic dermatitis.” In sections of tissue from a biopsy specimen taken from lesions in that patient, the authors took note of what they called “mycosis ...
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Precancerous melanosis: An obsolete term for lentigo maligna. Proliferation of atypical melanocytes confined to epidermis: Number of (proliferation) pigmented cells (melanocytes) not showing the normal cell structure (atypical). Not reportable.
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Squamous Cell Carcinoma A normal mole, like the one pictured here, is usually an evenly colored brown, tan, or black spot on the skin. It can be either flat or raised, round or oval. Melanoma is a cancer that begins in the cells that give skin its color. Normal moles also develop from these skin cells.
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Melanoma typically begins as a mole and can occur anywhere on the body. Squamous cell carcinoma may appear as a firm red bump, a scaly patch, or open sore, or a wart that may crust or bleed easily. Basal cell carcinoma may appear as a small white or flesh-colored bump that grows slowly and may bleed.
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A congenital nevus may become smaller or larger over time. In other cases, it might become darker, raised, and more bumpy and hairy, especially during puberty. In rare cases, they may disappear entirely. Congenital nevi usually don't cause any symptoms, but they're occasionally itchy when they're larger.
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Mildly dysplastic nevi are nevi that show this tendency to become very much larger than a normal nevus yet there is some central maturation. This can produce a "fried egg" appearance to the nevus. Mildly dysplastic nevi do not show asymmetrical colour variation or irregularity or edge.
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Dysplastic pulmonary stenosis is a less common variety with obstruction caused by myxomatous thickening of three separate but poor mobile leaflets without commissural fusion. It is associated with Noonan syndrome and hypertrophic cardiomyopathy.
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It is possible that most lesions currently reported as atypical melanocytic proliferation (AIMP or SAMPUS) are in fact benign, and that their significance lies in the potential pitfall for overdiagnosis of malignant melanoma.
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What It Is: The most common type of melanoma, representing about 70% of all cases. This melanoma usually appears as a flat or barely raised lesion, often with irregular borders and variations in color.
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A halo nevus is a mole surrounded by a white ring or halo. These moles are almost always benign, meaning they aren't cancerous. Halo nevi (the plural of nevus) are sometimes called Sutton nevi or leukoderma acquisitum centrifugum. They're fairly common in both children and young adults.
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Nevus of Ota is non-hereditary pigmentation disorder, which is more frequent in females than males. Unilateral presentation is typically seen, but bilateral involvement is described in 5–10% of patients.
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A: Dysplasia is a microscopic diagnosis made after looking at a piece of the oral tissue (biopsy) under a microscope. It means that there are premalignant changes that may progress to malignancy but there is no cancer.
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“Atypical junctional melanocytic hyperplasia” (AJMH) is a histological conceptual diagnosis that is made when the proliferation is “worse” than simple lentiginous melanocytic hyperplasia of a junctional or dysplastic nevus, but does not satisfy criteria for melanoma in situ.
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Nevoid Basal Cell Carcinoma Syndrome (NBCCS) is also known as Gorlin syndrome. NBCCS is a hereditary condition characterized by multiple basal cell skin cancers.
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Mildly dysplastic nevi do not show asymmetrical colour variation or irregularity or edge. Moderately atypical nevi do not show the central maturation of the fried egg nevus. They tend to be larger than normal junctional nevi with some variation of colour and edge.