what can cause high creatinine levels in blood?
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Generally, a high serum creatinine level means that your kidneys aren't working well. Your creatinine level may temporarily increase if you're dehydrated, have a low blood volume, eat a large amount of meat or take certain medications. The dietary supplement creatine can have the same effect.
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Any kind of heart muscle damage can cause an increase in CK and CK-MB, including physical damage from trauma, surgery, inflammation, and decreased oxygen (ischemia). Strenuous exercise may also increase both CK and CK-MB, but usually with a lower relative index. Kidney failure can cause a high CK-MB level.
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Eating too much food that is high in potassium can also cause hyperkalemia, especially in people with advanced kidney disease. Foods such as melons, orange juice, and bananas are high in potassium. Take certain drugs that prevent the kidneys from losing enough potassium.
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Early stage of chronic kidney disease is usually asymptomatic, and increased serum creatinine may be the only clue of underlying kidney disease. Serum creatinine level of 1.6 mg/dl means that, over 50% of kidney function is already lost, which is significant.
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['anemia.', 'bone marrow failure.', 'erythropoietin deficiency, which is the primary cause of anemia in patients with chronic kidney disease.', 'hemolysis, or RBC destruction caused by transfusions and blood vessel injury.', 'internal or external bleeding.', 'leukemia.']
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That said, creatine supplements should be approached with caution if you have a history of liver or kidney issues. SUMMARY Current research suggests that creatine does not cause liver or kidney problems.
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High blood pressure happens when the force of the blood pushing on the walls of your arteries is too high. This can damage or weaken the blood vessels around the kidneys, impacting kidney function and causing high creatinine.
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Non steroidal anti-inflammatory drugs (NSAIDs) Taking creatine with these pain relievers may increase the risk of kidney damage. NSAIDs include ibuprofen (Motrin, Advil) and naproxen (Aleve).
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The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration.
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['Caffeine.', 'Certain medications (such as nonsteroidal anti-inflammatory drugs) or combinations of medications.', 'Chronic kidney disease.', 'Cocaine use.', 'Collagen vascular disorders.', 'Overactive adrenal glands.', 'Pregnancy-related high blood pressure.', 'Scleroderma.']
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Parenteral use may cause allergic/anaphylactic reactions. Blood urea levels may rise in patients with compromised renal function due to severe heart failure [7]. Caution is recommended in pregnancy, lactation and patients dependent on preload for maintenance of cardiac output [8].
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Greater than normal intake of water will increase the urine water content (lowering the creatinine level) consequently diluting the amount of drug in urine. Conversely, a limited intake of water can lead to an abnormally concentrated urine specimen (as occurs with dehydration) resulting in elevated creatinine levels.
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['Abdominal surgery.', 'Alcoholism.', 'Certain medications.', 'Cystic fibrosis.', 'Gallstones.', 'High calcium levels in the blood (hypercalcemia), which may be caused by an overactive parathyroid gland (hyperparathyroidism)', 'High triglyceride levels in the blood (hypertriglyceridemia)']
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['Kidney injury, damage or failure.', 'Acute Interstitial Nephritis (AIN)', 'Bone fracture of the hip, wrist or spine.', 'Vitamin B-12 deficiency.', 'Clostridium difficile-associated diarrhea (caused by intestinal infection)', 'Lupus Erythematosus.', 'Low magnesium levels.']
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A serum creatinine test measures the level of creatinine in your blood and provides an estimate of how well your kidneys filter (glomerular filtration rate). A creatinine urine test can measure creatinine in your urine.
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Causes of CKD Often it's the result of a combination of different problems. CKD can be caused by: high blood pressure – over time, this can put strain on the small blood vessels in the kidneys and stop the kidneys working properly. diabetes – too much glucose in your blood can damage the tiny filters in the kidneys.
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The most common cause of genuinely high potassium (hyperkalemia) is related to your kidneys, such as: Acute kidney failure.