what are anti acetylcholine receptor antibodies?
314653
Anti-acetylcholine receptor antibodies are heterogeneous antibodies that cause loss of muscle function by several mechanisms. Anti-acetylcholine receptor antibodies are present in 80%- 90% of the patients with myasthenia gravis (MG) and 50-60% of patients with ocular MG.
446716
An acetylcholinesterase inhibitor (AChEI) is the inhibitor that inhibits acetylcholinesterase from breaking down acetylcholine into choline and acetate, thereby increasing both the level and duration of action of the neurotransmitter acetylcholine in the central nervous system, autonomic ganglia and neuromuscular ...
1002834
Anticholinergics block acetylcholine from binding to its receptors on certain nerve cells. They inhibit actions called parasympathetic nerve impulses.
164742
The patented Anti-Squalene Antibody Assay, or ASA Assay, is a test that detects antibodies to squalene in human blood.
725063
['Cholinesterase inhibitors. Medications such as pyridostigmine (Mestinon, Regonal) and neostigmine (Bloxiverz) enhance communication between nerves and muscles. ... ', 'Corticosteroids. Corticosteroids such as prednisone inhibit the immune system, limiting antibody production. ... ', 'Immunosuppressants.']
282848
['Acetylcholine, an ester of choline and acetic acid that serves as a transmitter substance of nerve impulses within the central and peripheral nervous systems. ... ', 'Acetylcholine is stored in vesicles at the ends of cholinergic (acetylcholine-producing) neurons.']
673210
Acetylcholine receptors are found on the surface of muscle cells, concentrated in the synapse between nerve cells and muscle cells.
1384547
Myasthenia gravis is an autoimmune disorder targeting skeletal muscles. Striated cardiac muscle can be a target for immune attack manifesting as heart failure, arrhythmia, and sudden death. We aimed to review cardiac manifestations of myasthenia gravis, its underlying pathogenesis and clinical relevance.
284632
Excessive accumulation of acetylcholine (ACh) at the neuromuscular junctions and synapses causes symptoms of both muscarinic and nicotinic toxicity. These include cramps, increased salivation, lacrimation, muscular weakness, paralysis, muscular fasciculation, diarrhea, and blurry vision[1][2][0].
777209
Myasthenia gravis. Myasthenia gravis (MG) is a long-term neuromuscular disease that leads to varying degrees of skeletal muscle weakness. The most commonly affected muscles are those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking.
817333
Acetylcholine receptor antibody is a protein found in the blood of many people with myasthenia gravis. The antibody affects a chemical that sends signals from nerves to muscles and between nerves in the brain. This article discusses the blood test for acetylcholine receptor antibody.
1335903
When acetylcholine binds to acetylcholine receptors on skeletal muscle fibers, it opens ligand gated sodium channels in the cell membrane. Sodium ions then enter the muscle cell, stimulating muscle contraction.
1274932
Acetylcholine receptor. ligand-gated ion channel: nicotinic acetylcholine receptorThe nicotinic acetylcholine receptor is an example of a ligand-gated ion channel. ... Upon binding acetylcholine, the channel opens and allows diffusion of sodium (Na+) and potassium (K+) ions through the conducting pore.
1170900
Acetylcholine. ... Acetylcholine is the chief neurotransmitter of the parasympathetic nervous system, the part of the autonomic nervous system (a branch of the peripheral nervous system) that contracts smooth muscles, dilates blood vessels, increases bodily secretions, and slows heart rate.
650386
Triggers for myasthenia crisis include disease exacerbations, noncompliance with cholinesterase inhibitor medication, adverse effects of other medications, fever, and emotional stress. Cholinergic crisis is secondary to excess cholinesterase inhibitor medication.
410656
Acetylcholine is actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter. It has a role as a vasodilator agent, a muscarinic agonist, a hormone, a human metabolite, a mouse metabolite and a neurotransmitter. It is an acetate ester and an acylcholine.
1111385
The mechanism and primary etiology of inappropriate sinus tachycardia has not been fully elucidated. An autoimmune mechanism has been suggested, as several studies have detected autoantibodies that activate beta adrenoreceptors in some patients.