what is the difference between acyclovir and ganciclovir?
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Ganciclovir is a nucleoside analog that differs from acyclovir by a single carboxyl side chain. This structural change confers approximately 50 times greater activity than acyclovir against CMV. Acyclovir has low activity against CMV because it is not well phosphorylated in CMV-infected cells.
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Aciclovir 800 mg Tablets contain a medicine called aciclovir. This belongs to a group of medicines called antivirals. It works by killing or stopping the growth of viruses. Aciclovir can be used to. treat chickenpox and shingles.
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Acyclovir topical ointment is used to treat genital herpes lesions. There is no cure for herpes and acyclovir will not prevent you from developing symptoms in the future. Acyclovir topical may also be used for purposes not listed in this medication guide.
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About aciclovir Aciclovir (or acyclovir) is an antiviral medicine. It treats infections caused by the herpes virus (herpes simplex), including: cold sores. genital herpes.
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For most infections, you should start to feel better after taking aciclovir for a few days. Common side effects include headaches, dizziness, and feeling or being sick.
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Aciclovir Tablets are indicated for the treatment of varicella (chickenpox) and herpes zoster (shingles) infections. Treatment of herpes simplex infections: 200 mg Aciclovir should be taken five times daily at approximately four hourly intervals omitting the night time dose.
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Aciclovir 400mg tablets are used to: • treat or prevent herpes simplex infections of the skin and mucous membranes e.g. cold sores and genital herpes (except in children whose immune system works less well and they are unable to fight infections) • prevent herpes simplex infections in patients whose immune system is ...
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Take acyclovir for the exact time prescribed by your doctor, even if your symptoms improve. Although acyclovir treats viruses, it is not effective against the flu or the common cold.
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Ganciclovir is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of cytomegalovirus retinitis (CMV retinitis) in individuals with AIDS.
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Aciclovir (ACV), also known as acyclovir, is an antiviral medication. It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein-Barr virus infection.
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Aciclovir is used to treat viral infections, such as chickenpox, genital herpes, shingles and cold sores. It is also used to prevent the infections in those with a lowered immune system. When taking aciclovir, it is best to drink a lot of water, to avoid dehydration.
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Acyclovir Side Effects. The most common side effects of acyclovir treatment for genital herpes include nausea, vomiting, and diarrhea. Shingles requires treatment with higher doses of acyclovir, and the most common side effects at higher doses are tiredness and malaise. Tell your doctor if you have any side effects.
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Hepatotoxicity. Despite widespread use, there is little evidence that acyclovir when given orally causes significant liver injury. Serum enzyme levels generally do not change during oral acyclovir therapy.
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Thus, clinicians most often utilize the anti-cytomegalovirus (CMV) agents ganciclovir (Cytovene® IV), cidofovir (Vistide® IV), and foscarnet (Foscavir® IV) for the clinical treatment of HHV-6 (Table below). CMV (HHV-5) is a beta-herpesvirus that is closely related to both HHV-6A and HHV-6B.
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Valtrex (valacyclovir) and Famvir (famciclovir) are antiviral drugs used to treat infections with shingles (herpes zoster), genital herpes (herpes simplex genitalis), and cold sores (herpes labialis).
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The tablets, capsules, and suspension are usually taken with or without food two to five times a day for 5 to 10 days, starting as soon as possible after your symptoms begin. When acyclovir is used to prevent outbreaks of genital herpes, it is usually taken two to five times a day for up to 12 months.
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Preclinical investigation brought the drug to clinical trials in 1977 and the first form of the drug (topical) was available to physicians in 1982. Activity of acyclovir is greatest against herpes 1 and herpes 2, less against varicella zoster, still less against Epstein-Barr, and very little against cytomegalovirus.