symptoms of lactic acid buildup?
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As our bodies perform strenuous exercise, we begin to breathe faster as we attempt to shuttle more oxygen to our working muscles. The body prefers to generate most of its energy using aerobic methods, meaning with oxygen. Some circumstances, however, --such as evading the historical saber tooth tiger or lifting heavy weights--require energy production faster than our bodies can adequately deliver oxygen. In those cases, the working muscles generate energy anaerobically. This energy comes from glucose through a process called glycolysis, in which glucose is broken down or metabolized into a substance called pyruvate through a series of steps. When the body has plenty of oxygen, pyruvate is shuttled to an aerobic pathway to be further broken down for more energy. But when oxygen is limited, the body temporarily converts pyruvate into a substance called lactate, which allows glucose breakdown--and thus energy production--to continue. The working muscle cells can continue this type of anaerobic energy production at high rates for one to three minutes, during which time lactate can accumulate to high levels.\n\nA side effect of high lactate levels is an increase in the acidity of the muscle cells, along with disruptions of other metabolites. The same metabolic pathways that permit the breakdown of glucose to energy perform poorly in this acidic environment. On the surface, it seems counterproductive that a working muscle would produce something that would slow its capacity for more work. In reality, this is a natural defense mechanism for the body; it prevents permanent damage during extreme exertion by slowing the key systems needed to maintain muscle contraction. Once the body slows down, oxygen becomes available and lactate reverts back to pyruvate, allowing continued aerobic metabolism and energy for the body’s recovery from the strenuous event.\n\nContrary to popular opinion, lactate or, as it is often called, lactic acid buildup is not responsible for the muscle soreness felt in the days following strenuous exercise. Rather, the production of lactate and other metabolites during extreme exertion results in the burning sensation often felt in active muscles, though which exact metabolites are involved remains unclear. This often painful sensation also gets us to stop overworking the body, thus forcing a recovery period in which the body clears the lactate and other metabolites.\n\nResearchers who have examined lactate levels right after exercise found little correlation with the level of muscle soreness felt a few days later. This delayed-onset muscle soreness, or DOMS as it is called by exercise physiologists, is characterized by sometimes severe muscle tenderness as well as loss of strength and range of motion, usually reaching a peak 24 to 72 hours after the extreme exercise event.\n\nThough the precise cause of DOMS is still unknown, most research points to actual muscle cell damage and an elevated release of various metabolites into the tissue surrounding the muscle cells. These responses to extreme exercise result in an inflammatory-repair response, leading to swelling and soreness that peaks a day or two after the event and resolves a few days later, depending on the severity of the damage. In fact, the type of muscle contraction appears to be a key factor in the development of DOMS. When a muscle lengthens against a load--imagine your flexed arms attempting to catch a thousand pound weight--the muscle contraction is said to be eccentric. In other words, the muscle is actively contracting, attempting to shorten its length, but it is failing. These eccentric contractions have been shown to result in more muscle cell damage than is seen with typical concentric contractions, in which a muscle successfully shortens during contraction against a load. Thus, exercises that involve many eccentric contractions, such as downhill running, will result in the most severe DOMS, even without any noticeable burning sensations in the
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Go see a doctor. It could be some serious conditions that may result in damage to your body. Don't take a chance. Below are the two most likely. Take care of yourself.\n\n\n\nDiabetic Ketoacidosis signs may refer to those signs only noticable by a doctor: \n\nNausea \nVomiting \nBreath odor \nSweet-smelling fruity acetone breath \nBreathing difficulty \nRapid Pulse \nRapid breathing \nAbdominal pain - usually in children \nDrowsiness \nConfusion \nComa \n\n\n\nKetoacidosis is a type of metabolic acidosis which is caused by high concentrations of keto acids, formed by the deamination of amino acids. This is most common in untreated type 1 diabetes mellitus, when the liver breaks down fat and proteins in response to a perceived need for respiratory substrate. Ketoacidosis should not be confused with ketosis, which is one of the body's normal processes for the metabolism of body fat. In ketoacidosis, the accumulation of keto acids is so severe that the pH of the blood is thrown off.\n\nIn diabetic patients, ketoacidosis is usually accompanied by dehydration, hyperglycemia, and insulin deficiency. Since insulin is required to utilize glucose, lack of insulin means the body cannot utilize glucose and causes an energy crisis and the body goes to extremes to produce more glucose and also provide ketone bodies for energy. Glucose accumulates to the point that the kidney must use water to spill it into the urine, losing that water and causing dehydration in the process. The dehydration exacerbates the acidosis in a vicious cycle.\n\nAlcoholic ketoacidosis is also an energy crisis but of different origin. Because alcohol causes dehydration and blocks the first step of gluconeogenesis, the body is unable to synthesize enough glucose to meet its needs, thus the energy crisis begins.\n\nThe acidity results from the dissociation of the H+ ion at physiological pH of metabolic ketone bodies such as acetoacetate, and β-hydroxybutyrate, produced from ketogenesis and its concentration is increased by dehydration.\n\nSome diets (such as the Atkins diet) are reported to induce a mild-to-moderate state of ketosis, but this does not result in ketoacidosis if the dieter drinks an appropriate amount of water. Any diet which burns fat molecules at a significant rate results in an increased production of ketone bodies.\n\nGenerally, ketosis is well-regulated by the milieu of hormones governing the fasting and fed states, predominantly glucagon and insulin, and dieting (in an otherwise healthy person) is too mild to lead to acidosis. Before the recent abundant and sedentary lifestyles, it was probably normal for most humans to spend some of each year in ketosis, due to seasonal or temporary carbohydrate and/or calorie shortages. Unlike ketoacidosis, for most of human history, ketosis has been a normal condition and an essential capability.\n\nKetoacidosis occurs in two very different situations-- in type 1 diabetes (diabetic ketoacidosis) and in alcohol withdrawal (alcoholic ketoacidosis). The ultimate reason for ketoacidosis in both cases is the same: the cell does not have enough glucose (in the case of diabetes because lack of insulin prevents the cell from taking up glucose, in the case of starvation because there is less glucose around), so it begins metabolizing fat molecules instead of simple sugars. As a result of this metabolic change, acetyl-CoA is mainly produced from the breakdown of fatty acids and fed into the citric acid cycle. The intermediates of the citric acid cycle are used for other anabolic purposes as well and have to be replenished. Normally, this is done by converting pyruvate into oxaloacetate or L-malate (the so-called anaplerotic pathways). But pyruvate is the end product of glycolysis, the breakdown of glucose, and glucose levels are lower in the cases we consider. This means that the citric acid cycle intermediates cannot be replenished, the cycle slows down, acetyl-CoA accumulates and ketogenesis becomes more impor
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Trowing up, no appetite, sleepingg alot, extreme fatigue\n\nbreast tenderness\n\nnausea, with or without vomiting\n\nconstipation, gas, and/or bloating\n\nabdominal cramps\n\nfrequent urination\n\nfood cravings or aversion\n\nmood swing\n\nincreased vaginal discharge
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First of all, get a hold of the book " The Yeast Connection and the Woman" by Dr. William G. Crook. Read it cover to cover! By the way: It does not just apply to women.  I have been there, so I sympathize, and I will tell you it is a long tough road. Candida thrives in an acidic environment.  The American Diet is 80% acidic, 20% alkaline typically.  In order to get healthy those percentages need to be turned to 20% acidic, 80% alkaline! What are acidic foods? All white flours and sugars, everything processed and made with corn syrup, dextrose, sucrose.  You have to AVOID these at all costs! What is alkaline? Healthy foods!  Fruits, veggies, meats, whole grains.  Candida thrives in an acidic environment.  What is the best cure?  FOUR THINGS:  WILD MOUNTAIN OREGANO OIL, LOTS OF FRESH CHOPPED GARLIC, AND GRAPEFRUIT SEED EXTRACT, and PH balance pills (VAXA makes these). Don't forget to drink plenty of pure water. WHILE TAKING THESE FOUR REMEDIES, MAKE SURE YOU EAT PLENTY OF ACIDOPHILIS (YOGURT, ACIDOPHILIS PILLS).  IT IS NEEDED TO REPLACE THE GOOD BACTERIA IN YOUR SYSTEM.  WHEN CANDIDA OCCURS, THE BAD BACTERIA HAS OVERTAKEN THE GOOD, CAUSING FAR REACHING PROBLEMS.  TIREDNESS, MOOD SWINGS, ALLERGIES, SKIN PROBLEMS, MEMORY LOSS, CHRONIC FATIGUE, THE LIST IS ENDLESS.  CANDIDA CAN ALSO MIMIC THE SYMPTOMS OF OTHER DISEASES.  It also does not disappear overnight.  Sometimes an individual does not see improvement for a few months, and will have die off symptoms before they feel better.  Stick with the restrictive diet, and remember when you cheat, the bad bacteria is allowed to grow again, because CANDIDA LIVES ON SUGAR (THE HERB STEVIA IS A LIFESAVER IF YOU NEED A SUGAR REPLACEMENT IT IS 300X SWEETER THAN SUGAR AND IS NATURAL) Stay away from Nutrasweet, saccharin, Splenda-these are all chemicals that will cause more problems!!  One more thing:  If you have Candida, chances are you have a parasite problem as well.  Be sure to do a parasite cleanse also.  Parasites can also cause far reaching problems.
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I have been checking some notes that I have.  Earl Mindell says to increase your Omega-3 fats.  I have found a study that says that aspartame (the component in no-cal sugars) can cause lupus.\n\nPeople with lupus or other autoimmune diseases should not eat – I-canavanine, a compound in alfalfa, can trigger an autoimmune response in the body similar to lupus.\n\nFor Potassium, I found: Deficiency Symptoms: Gastrointestinal disorders; Irritability and depression; Lupus (mega-doses have shown a positive response in 80% of cases studied)\n\nSulfur Deficiency: Degeneration of cartilage, ligaments and tendons, Lupus, Several collagen diseases, Sickle cell anemia \n\nIt has been claimed that supplementation with pharmacological doses of pantothenic acid (vitamin B5) may alleviate the symptoms of rheumatoid arthritis and lupus erythematosus.\n\nAnd one I did not expect to find:  Water cures ... lupus...  These conditions are caused by prolonged chronic dehydration.  In these conditions exercising one's muscles should be part of the treatment program.\n\nLots of different information, but some good leads.  I would try one or all of them.
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Those may not be symptoms of Grave's; instead, you may be experienceing perimenopause, GERD, etc.  I would certainly investigate the symptoms, but the blood test for Grave's tells the story -- you are now in remission.  \n\nIf your doc is an endocrinologist, that would explain why he had not addressed your issues -- your GP will be the one to do so, likely ordering other blood tests, etc.  However, if the doc you speak of is your regular doctor, you need a second opinion.
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Sounds like  a blood-sugar problem
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I just became lactose intolerant about a month ago. It started with awful bloating, gas, and some of the worst diarrhea I have ever had.\n\nI'm doing much better now that I have started taking these once daily pills. They work a lot better for me than lactase pills that I originally began taking.\n\nYou can find info about them at http://ganedenbiotech.com/index.php?page=DALI\n\nIf you try those pills, just be aware that it may take some time before they begin working all day long and you may have to take 2 daily like me.
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You can not detect when you will get it.  You can know the things that will lead to it....those are the things that will make your sugars go too high for too long...generaly people will begin to feel tired / thirsty and urinating alot.  It is all the same disease...sugars getting out of hand.  We say you develop the acidosis based on the lab results...this is how it is known that you are no longer using sugar for energy but rather fats.  The use of these fats for energy leads to the by-product we call ketoacids.  You can't know they are there but you should see it coming as part of the whole sugars out of control picture.  The number one problem leading to DKA is non-compliance with diet and meds.  Stressed out...overworked...infections...pregnancy and anything else that puts stress on you will bring it on.  Alot of people find out they have DM when go to the hospital with DKA...usually a young man or woman.
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Yes this means you are in ketoacidosis.  Your blood sugar has ran so high your body is compensating for it.  The fruity odor is a definitive sign of ketoacidosis.\n\nSeek medical attention today!
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I have been lactose intolerant for years.  There are many different symptoms, but I think the most common ones are cramps, diarrhea, constipation, bloating.  In my case, it even gave me horrible migraines.  You can use Lactaid products and pills to ward off any of those uncomfortable symptoms when eating dairy products or even try soy products instead of dairy.  They now make milk, cheese and all sorts of great, tasty food with no dairy whatsoever.\n\nI agree with thepathfinder804's answer too; that's exactly what I did to verify if I was lactose intolerant: I stopped all dairy consumption for 1 month and tried again 1 day and I knew then and there that I was lactose intolerant.
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Lactose Intolerant. \n\nLactose intolerance occurs when the body cannot easily digest lactose, the kind of sugar found in milk and dairy products. This happens when the small intestine does not make enough of an enzyme called lactase. Your body needs lactase to break down, or digest, lactose. \n\nWhen lactose moves through the large intestine (colon) without being properly digested, it can cause uncomfortable symptoms such as gas, pain in the belly, and bloating. Some people with lactose intolerance cannot digest any milk products while others can eat or drink small amounts of milk products or certain types of milk products without problems. \n\nLactose intolerance is common in adults. The biggest challenges for people who are lactose-intolerant are knowing how to eat to avoid discomfort and getting enough calcium to maintain healthy bones.
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My mother had the EXACT same symptoms.  They ran EKG and bloodwork and chest x-ray and also said nothing was wrong.  Two years later, she is being tested for Multiple Sclerosis every 6 months (it can take up to 10 years to show on catscan).  My advise would be to make sure you see a doctor and get a CATSCAN.  Also, it could be acid reflux.  My mom said it felt like a heart attack.  As strange as it sounds, acid reflux can cause these exact symptoms.  She takes prilosec for that.  But now they think it may have been related to muscle spasms caused by MS.  Be firm with doctors and don't give up.
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sounds like heartburn or acid reflux, go to the supermarket or CVS and pick up some over the counter stuff
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Usually you will get gas pain in your side or lower gut. Or, you might get a rash (like I do) on your face. Both reactions will go away eventually, but your body clearly wants to keep you away from dairy! I like soy milk for that very reason!
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I'm afraid we're in the same boat as you.  I can eat small amounts of cheese, yogurt, ice cream, and butter without symptoms...but if I eat them too frequently, or in large amounts, then it's the usual symptoms...and no, Lactaid doesn't always work for me either.\n\nYou have to learn moderation...and to do without the things you used to love (mmm...milk), if, like me, your allergy developed later in life.  It sucks, yes...but you learn to live with it.\n\nLarge amounts of soy-based products can have adverse affects as well...and I personally cannot stand soy-based substitutes...but that's me.  \n\nAs for lactose-free items....those are mostly safe, but sometimes even the lactose free milk (Lactaid) will still bother me.\n\nNot sure about the watercress thing...hadn't heard that one before.
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Signs and Symptoms of Caffeine Intoxication or Abuse\n \nnervousness, headache, increased heart rate, anxiety,            upset stomach, irregular heartbeat,  irritability, GI irritation, elevated blood pressure,  agitation, heartburn, increased cholesterol, tremors, diarrhea, nutritional deficiencies, insomnia, fatigue, poor concentration, depression, dizziness, bed wetting.\n \nCaffeine Withdrawal Symptoms\n \nheadache, constipation, runny nose, craving,                            anxiety, nausea, irritability, nervousness, vomiting, insomnia, shakiness, cramps, fatigue, dizziness, ringing in the ears, depression, drowsiness, feeling hot and cold, apathy,           inability to concentrate\n\n                                                      ****\n\nMany disorders of the human immune system fall into two broad categories that are characterized by:\n\nWeakened immune response: \n\nThere are 'congenital' (inborn) and 'acquired' forms of immunodeficiency, characterized by an attenuated response. Chronic granulomatous disease, in which phagocytes have trouble destroying pathogens, is an example of the former, while AIDS ("Acquired Immune Deficiency Syndrome"), an infectious disease caused by the HIV virus that destroys CD4+ T cells, is an example of the latter. Immunosuppressive medication intentionally induces an immunodeficiency in order to prevent rejection of transplanted organs. \n\nOverzealous immune response: \n\nOn the other end of the scale, an overactive immune system figures in a number of other disorders, particularly autoimmune disorders such as lupus erythematosus, type I diabetes (sometimes called "juvenile onset diabetes"), multiple sclerosis, psoriasis, and rheumatoid arthritis. In these, the immune system fails to properly distinguish between self and non-self, and attacks a part of the patient's own body. Other examples of overzealous immune responses in disease include hypersensitivities, such as allergies and asthma. \n\nOther factors that affect immune response:\n \nMany factors can also contribute to the general weakening of the immune system:\n\nMalnutrition (unbalanced diet / poor eating habits that cause a lack of vitamins, minerals and Polyphenol antioxidants) \nAlcohol abuse \nDrug abuse either intravenous or other. (Appears related to associated factors i.e. poor diet, use of infected/dirty needles, poor exercise, stress/depression) \nMedications (particularly the use of anti-cancer drugs, corticosteroids, and antibiotics); \nRadiation \n\nExposure to certain environmental toxins, whether naturally occurring or from pollution. These include: \nCigarette smoke \nStress/Depression - Research shows that psychological stress can greatly increase your susceptibility to colds and other viral diseases, namely through an increase in serum corticosteroid levels \nAge - Ability of the immune system to respond is decreased at early and old age. \nDecrease ability to heal due to disease or medications (i.e. Diabetes, corticosteroids, immune suppressant drugs), causing constant exposure to infectious agents without natural defense (intact skin) \nInadequate sleep at the Delta brain wave level. According to a sleep study, we need 4 hours of Delta sleep every night \nLack of exercise as well as excessive exercise resulting in physiological stress \nLong-term weightlessness \n\nDiseases either infectious or other causing more depression on the immune system like: \nCancer, and hematological malignancy (such as leukemia, lymphoma and myeloma) in particular. \nDiabetes Mellitus \nCystic fibrosis \nLupus Erythematosus \nNephrotic syndrome \nViral infections i.e. viral respiratory infections then allowing for bacterial pneumonia to develop. \nHIV \nUlcerative colitis \nBulimia (due to malnutrition, stress, depression). \nSickle-cell disease. \nLiver disease / cirrhosis \nCushing's syndrome \nProtects \nHuntington's Chorea