how is preparation platelet rich plasma?
966155
You are talking blood donation I assume? When one donates blood, it is done in a closed system. There is a primary collecting bag with 2 satellite bags off the side. No air must be introduced.\n\nThe donated blood is given a light spin, this will separate the red cells from the plasma rich platelets. This platelet rich plasma is then transferred to the first satellite bag. The RBC bag is separated from the satellite bag using a dielectric sealer, so to keep air out, and keep it a closed system.\n\nThe bag of platelet rich plasma is then given a hard spin, so to separate the platelets from the plasma, the excess plasma is allowed to flow into satellite bag #2, leaving just enough plasma in the platelets to suspend. Bag 1 is pooled platelets, Bag 2 is plasma. The two bags are separated again by the dielectric sealer to keep air out again keeping the integrity of the closed system.\n\nBag 1 can be kept at room temperature for up to 5 days.\nBag 2 will be frozen. Frozen it will keep up to one year.\nHowever once you thaw it, you must use it. You cannot re-freeze.\nWhere I work, thawed FFP is good for up to 5 days.
522832
platelets are just fragments of the large bone marrow cells known as megakaryocytes... \n\nand the red blood cells, or erythrocytes, have no nucleus... \n\nso he should obtain any of the white blood cells, or leukocytes, such as neutrophils granulocytes, eosinophil granulocytes, basophil granulocytes, lymphocytes, monocytes or macrophages... because it is a complete cell with an intact nucleus, where the dna is located...
617227
I'm assuming that you mean recieving it..as in a transfusion...there is a VERY small risk of contracting a disease because of the procceses that it goes through. I dont even know if there have been any recent cases of that heppening. there is also a small chance of an allergic reaction but plasma doesnt have the antibodies that whole blood or platlets does so the chance is pretty unlikely. plasma is a relativly safe and life saving product.
251997
Roto rooter of the alimentary canal...\n\nI had one several years ago. The prep is worse than the procedure.  You can't eat anything solid for 3-4 days prior, and only drink clear liquids.  Then, you have to drink some stuff that cleans you out the night before you go in for the procedure.\n\nAs for the procedure itself... Mild discomfort, but mostly embarrassing. Imagine laying on your side while a total stranger shoves a TV camera up your bum!  \n\nSmile for the camera!
1182765
In the spring of 1984 I had a foot long blood clot in my right leg in the calf area.  Blood clots are often referred to as thrombophelbitis meaning a deep vein blood clot.  I was in the hospital for 3 wks and had to remain in bed.  The doctor tested my blood, and he told me I had blood the consistency of frozen ketchup!  So he put me on Coumaden.  He tried the pill form, but it wasn't working, so he gave it to me thru a i.v.  After several days had passed, my blood still wasn't thinning out like he had hoped so in addition to the i.v. Coumaden, he ordered shots of Hepburn several times a day in my stomach area.  After awhile things were starting to look better, until the nurse went to get a sample of my blood and I was bleeding really bad, all over the bed and floor.  The doctor had to eliminate the Hepburn shots and slowly after a period of a few more days, my blood returned to normal again.  \n\nWith modern technology, I am certain by now, the treatment is a lot better than it was back in 1984.\n\nI hope this is helpful to you!  Good luck and I hope you feel better soon!!
281304
as blood escapes from a openiong in a blood vessel, platelets react to oxygen changes in the blood and become sticy and the large irregular shape of platelets pack together and create a seal to halt further blood loss.
550119
Donated blood only lasts 28-42 days. Platelets, which contain clotting agents, last only 5 days.
561843
The most interesting question of the day, so I had to do some research. While I thought it was impossible because of the antigens present in blood types, this article seems to indicate that it can be done. That sure will relieve blood supply issues.
503727
New Techniques Safely Remove Deep Vein Clots\nThey're also quicker, saving health-care costs, studies find \nBy Janice Billingsley\nHealthDay Reporter\nFRIDAY, April 1 (HealthDay News) -- New techniques that aid in dissolving and removing blood clots in the legs could improve treatment for this painful and often dangerous condition, researchers report.\nDeep vein thrombosis (DVT) affects approximately 250,000 people annually, and about half of them go on to suffer from chronic leg pain and swelling, called post-thrombotic syndrome, said Dr. Suresh Vedantham, assistant professor of radiology and surgery at Washington University, in St. Louis.\nThe condition has received considerable media attention in the past few years after striking passengers on long-distance flights. Many airlines now advocate that passengers do simple exercises during flights to maintain healthy circulation in the legs.\n\nThe most common DVT treatment -- a blood-thinner medication that prevents new clots but does not remove the existing clot -- could be improved upon, Vedantham said. "It's been sort of recognized that removing the clot is a better treatment than blood thinner, but the previous treatments to do this are not user-friendly," he said.\n\nThe traditional clot-removing treatment, called catheter-directed thrombolysis, involves an infusion of anti-clotting medication that takes as long as two days to break down the clot. The procedure also requires careful monitoring, with a follow-up in a hospital's intensive care unit. Less than 5 percent of individuals with deep vein clots undergo the procedure, Vedantham said.\n\n"The holy grail for us has been, 'Can you remove the clot in one step,' and these [new] techniques may turn out to be what we've been seeking for a long time," he said.\n\nVedantham presented research on three of these new technologies on Friday at the Society of Interventional Radiology's annual scientific meeting in New Orleans.\n\nThe first, called the Power Pulse Spray, delivers clot-dissolving medicine at a high force which helps break up DVT by spreading the drug over a surface area of the clot. Thirty minutes later -- when the clot begins to partially dissolve -- the spray is used to create a vacuum so the clot can be sucked into a catheter and removed.\n\nIn studies of the device, 80 percent of 14 patients who tried the technique were treated in a single session, and in 10 cases (71 percent), the clot was completely removed. Three of the patients had a substantial removal of their clots while one achieved only a partial removal.\n\nA second method, called The Trellis(r)-8 Infusion System, first isolates the clot by surrounding it with inflated balloons to minimize bleeding. Doctors then insert a thin vibrating wire filament into the blockage, effectively chewing up the clot. The clot fragments are then pulled into a catheter and removed from the body.\n\nA study compared the Trellis technique to the traditional catheter-directed thrombolysis. The researchers report that patients who underwent the vibrating wire treatment experienced a lower risk of bleeding and required lower doses of clot-dissolving medication. The procedure also took less time, saving hospital costs.\n\nVedantham also reported on a third technique, the HELIX Clot Buster, a device that works by chewing up the clot. Unlike the other two devices, HELIX is not yet approved by the FDA for use in DVT, although it is FDA-approved for clots related to dialysis, the researchers said.\n\nIn an eight-year study involving 36 patients -- 11 of whom had the traditional method of clot removal, and 25 of whom were treated with the HELIX -- researchers found no difference in the overall 86 percent success rate of the two therapies in removing the clots.\n\nIn the HELIX group, however, treatment time was significantly shorter and the dose of anti-clotting medicine required was half that of traditional interventions. There was
937364
The procedure is basically painless in 99% of the people who've had one. You just feel a little pressure as they take a small sample. The skin is numbed so you don't feel any surface pain. The liver doesn't have many nerves inside, so there is little discomfort. The hardest part is lying on your side for 2-4 hours afterwards. It sounds worse than it is. I've had one. Best wishes.
232651
Platelets are colorless, irregularly shaped bodies in the blood.  Their "job" is to form clots to stop bleeding.  They are sticky and will rush to an injury and then stick together to form a clot with the help of Vit K and fibrinogen (a protein) to help stop bleeding.  This clot will eventually become a scab.
688387
Hmm...Im not sure but the spleen is the major site of platelet destruction, but removal of the spleen will only bring up the platelet count in 50% of people.\n\nOther treatments when the disease does not respond to initial treatment are:\n\nOral danazol \nHigh-dose gamma globulin injections \nDrugs that suppress the immune system \nPassing the blood over a protein A (Prosorba) column, which filters antibodies out of the blood stream \nAnti-RhD therapy can also be useful in people with specific blood types \n\nMAYBE!!!In children, the disease often runs its course without treatment.\n\nHope this helps
243882
Thrombocytopenia is the medical term for "Low Platelet Levels" in the blood.  Platelets, as you might know, are the smallest membrane-bound components of the blood made in the bone marrow by cells called megakaryocytes and are released into the bloodstream.  Their major function is induction of "Hemostasis" which means control of bleeding.  When a blood vessel's integrity is compromised and bleeding ensues, certain chemicals are released from the injured vessel's cells that activate and stimulate the platelets to aggregate and form a "platelet plug." This will help stop bleeding and form a platform on top of which coagulation factors give rise to fibrin and further ensure hemostasis.\n\nSo the bottom line and summary is that platelets are involved in control of bleeding.  In certain medical conditions, the number of platelets in the blood decreases below a normal range; we call this thrombocytopenia. In this case, the patient falls under high risk of severe bleeding if injured. Therefore, as part of the nursing care for thrombocytopenic patients, one must ensure that the patient is not at high risk for falls or other types of injury that may place them at risk for excessive bleeding. Certain concommittant medical conditions such as hyperglycemia in diabetes, uremia in renal failure, immune thrombocytopenic purpura (ITP), DIC, sepsis, and patients taking blood thinners such as aspirin or clopidogrel (plavix) one must be particularly aware of the platelet status, because all of these conditions cause malfuntioning of the existing platelets and may lead to severe, even spontaneous bleeding through mucosal surfaces, intravenous lines, etc.\n\nNormal platelet rage in the blood is 150,000 to 350,000 per mL of blood.  Thrombocytopenia to as low as 50,000 may be tolerable, but lower levels are associated with higer risk of bleeding and the patient might require platelet transfusions.\n\n\nF. Rafii\nYear III Doctoral Candidate\nKeck School of Medicine\nUniversity of Southern California
517868
Let your food heal you\n\nFolic acid are needed for the production of red and white blood cells and platelets.\n\nEat Bannanas and Oranges, Spinach, eggs, and Lima Beans.\n\nTake Prenatal Vitamins with etra Iron\n\nTake MSM supplement for sulfur\n\nTake Extra Vitamin C until Diahrhea begins then back off\n\nI would also take cottage cheese with cold flax seed oil in a frut cocktail\n\nI would do the Water Cure\nhttp://curezone.com/foods/watercure.asp\n\nI would take a tablespoon of apple cider vinegar in carrot juice with cinnamon every day.\n\nhttp://curezone.com/blogs/f.asp?f=179&p=1
513991
The only way to prevent is by taking coumadine or wafarin.  The sticky platelets are caused by an error in the "coagulation cascade" -- there are 13 factors that impact coagulation, including calcium.  When one of the factors doesn't work properly, platelets can get sticky.  There can also be too many platelets in the blood, essentially causing a traffic jam or blood clot.  Without running the coagulation studies, or having more info, it's a little difficult to explain the "why" of it.  The important thing is that your son and husband take their medication **** and I CANNOT stress this enough **** get their levels checked regularly.  Blood thinners are insanely unstable, and the dose that works one day, may be too much the next.  Keep seeing the doctor, stay on top of this with the medications.  There is not a procedure that would "cure" this; there are some extreme cases where the people need to have platelet phoresis (a process in which the blood is run through a machine that removes the platelets and then the blood is put back into the person).  Good luck to you, and your family.
569570
Dr Folts did the research on aspirin and it's roll as a anti platelet, he also found it does not work when the human body is under stress (when most heart attacks occur). He has been researching other alternatives and the best one to date is Grape seed extract. He has a patented formula marketed through a private company but it would be solicitation to say who it is here. But regular GSE is good for you also.
662126
Recently prepared to me would be a day or two. Freshly prepared would me they just made it 10 minutes ago or so. You would only say this is you were making IV fluid or you were compounding something (making a suspension, solution, eye drops, ointment, creams, vaccines, etc). \n\nThe guy above me is talking about compounding medication. I compound medication at the hospital. Sometimes a medication will only come in a tablet form. If the patient is unconscious or for some reason can't take a tablet, sometimes we can crush it (depending on the med) and make it into a suspension. This is usually done in a hospital or a pharmacy that specializes in it. Your local Walgreen's or Osco usually doesn't do this.\n\nHope that answered your question.