if you have had retinolblastoma, and you are now pregnant,what are the chances of your baby having it?
920973
Since the retinoblastoma is an inherited form, one of the 2 copy of RB gene must be mutant type i.e. she is a carrier. RB gene is a tumour suppressor gene, so both copies need to be mutant in order for a tumour phenotype to be observed i.e. it's recessive. \n\nNow, you have to ask your sister husband, did his dad, mum, grandpa, grandma and himself had retinoblastom. i assume he is a healthly individual, but if any other his family member menthioned above had retinoblastomer, he might be a carrier, thus if 2 carriers mate, the progeny carrying double RB mutation won't survive in the mother's womb\n\nif the child is born, and you know the father is wild type and the mother is carrier, there is 25% for the child to be a carrier too.\nbeing a carrier is not enough to cause the disease, a second mutation will be required, and the probability of this depends on the environment the child is around. for a child carrying one mutated RB to obtain a second mutation of the wild type copy under normal condition during his life time is about 2% \n\nso the probably of the child being a carrier and obtain a second mutation later in life is 0.25 x 0.02 which is 0.005 about 0.5% assuming the father is completely healty i.e tow copy of wild type RB gene in his gametes. \n\nif the father is a carrrier also, the problematic double mutant child won't survive before parturition i.e. fetal death, and offspring that did live to postpartum should then carry the wild type RB genes  and the chance for double mutation of the 2 wild type copy will be low and this child will only have sporadic form of retinoblastoma, thus this child's offspring won't inherit RB mutant copy from this child.
581791
First of all, try to be as calm and well-informed as possible.  Communicate with trusted friends and relatives.  Have a doctor you can talk with often. I just went to About.com to look up cancer in pregnancy, and they \nhave an entire section devoted to that. Go to: \nhttp://pregnancy.about.com/od/cancerinpregnanc/ --or go to About.com, then Pregnancy/Birth, then Pregnancy Complications, then Cancer in Pregnancy. Print out or write down anything that scares you (even more)or that is unclear or that you need your doctor's opinion about.  Make a doc appt. to discuss everything.  Also visit the WebMD site. Stay well-informed and do not panic. Everyone's circumstances are different, remember that!
23138
You should immediately tell your boss. Xrays cause fetal defects. You should not be exposed to radiation at any level during pregnancy.
301408
only if you're pregnant.
845985
You'll want to wait until the baby is older.  You'll be in the hospital for a few days and very sore from surgery afterward.\n\nKeep in mind that bariatric surgery isn't a cure all.  At the Kimkins Diet site we have members who had surgery and still remained overweight because they didn't change their food choices.\n\nIn addition, you'll find it difficult to eat many foods.  They don't fit through the new small stomach opening.  \n\nWhat you WILL be able to eat is plenty of high calorie food that turns liquid and passes right through like mashed potatoes, gravy, sugar cereal, milk, soda, cheesecake, pastries, rice, beer, milkshakes, candy, rum, wine and vodka.
290330
if you get pregnant your breast will get larger
677013
All i know is that women should not attempt to get pregnant until 6 months has passed from the treatment. But discuss this with the oncologist. Your girlfriend will need Thyroxin\nhormone as a form of tablet every day for the rest of her life, as there will be no hormone production in the thyroid gland, especially if they plan to remove the thyroid later (thyroidectomy).\nI am not aware of any recurrence of leukemia or other cancers, but this is something that you could discuss with the oncologist. Write all the questions down and demand an answer :)\nSome patients who have hyperthyroidism (overactive thyroid) also undergo radioactive iodine treatment.
339936
Based on your question, I'm not sure how to answer.  But if you know of a woman who has cancer and wants to or is pregnant, I think all depends on what type of cancer, the treatment, etc.  Best if an expert like a medical doctor is consulted.
788709
Firstly congrats on surviving this nasty cancer.\nAs for having children, you may need to see a fertility specialist, there is some talk that the treatment protocols for leukaemia can make you infertile because they are so strong.\nIf you are able to have children, i dont believe there would be an issue of your child getting leukaemia, it is not ment to be genetic. But I would also see a genetic councillor if you are able to have children. Good luck!
45749
Up to a year, most of the nutrition should be from ideally breastmilk or at least formula.  I wouldn't worry too much for now.  You might try other types of food, but I would stick to the essentials (Gerber stage 3 equivalent if there are a couple of teeth or so.\n\nIf it occurs for too long, talk to your pediatrician about it at the next regular visit.\n\nIf there is any weight loss or any serious concern, go sooner.\n\nGood luck!
799128
No. The mother needs to be RH- and the baby needs to be RH+ in order for the baby to have erythroblastosis fetalis, and it will happen only after the first child.
916323
Yes,there should be worried if father is Rh+ and mother is Rh-.This also may not creat problem for thier first child because mother blood has not started  making antigen against Rh+.But after thier after thier first child has been born then, of course, mother has started making antigen.Then thier second child child will die of embryonic erythroblastosis.I think you have understand the process.
1171333
SORRY TO HEAR ABOUT THE FIBRO I ALSO HAVE IT AS WELL AND I KNOW EXACTLY HOW YOU FEEL. ITS A HORRIBLE THING TO HAVE AS FAR AS BEING PREGNANT WHAT DO YOU MEAN? AS FAR AS MORE PAIN AND THE PAIN MEDS IF YOUR ON THEM AND BEING PREGNANT OR WILL THE FIBRO HARM THE BABY? SORRY DIDNT NO WHAT YA WERE LOOKING FOR BUT IT WONT HURT THE BABY DUE TO THE FIBRO AND MORE PAIN? MORE THEN LIKELY I THINK I HAD IT WHILE I WAS PREGNANT BUT THATS BEEN 18 YRS AGO I AM 40 MY SONS GIRLFRIEND IS PREGNANT SHE TO HAS FIBRO. BUT....I WOULD LOVE TO TALK MORE WITH YOU ABOUT THIS SO PLEASE EMAIL ME IVE BEEN LOOKING FOR PEOPLE TO TALK TO CONCERNING THIS GOOD LUCK TO YOU LANAY   lanay40@yahoo.com  i will be waiting to hear from you thanks
346326
This is not a stupid question.\n\nAre you referring to a baby still getting breast fed? Who knows? Maybe it can cause Breast Cancer.
455062
not sure.. ask your doctor.. i think you may lose the baby.. bc doctors always make you take a pregnancy test before perscribing them to me... i kno that.. much..
284803
X-rays should be avoided in the 1st trimester, if at all possible.  Cells are dividing at such a rapid rate, there are more chances of mutating them at this point.\n\nFor a 7th month pregnancy, the risks are not as great.  It is not much different from a newborn getting an x-ray.  BUT, I have rarely done an x-ray on a pregnant woman, other than in trauma situations, when a diagnosis could make the difference between life and death.\n\nHere is what some "experts" say:\nThe fatal cancer risk is not measurably elevated by the chest x ray during pregnancy. The American Cancer Society provides comparison data for cancer incidence. The Society estimates that the lifetime risk of developing invasive cancer at any age in an American today is 43.48% in a male and 38.34% in a female. The probability of developing cancer as a result of the chest x ray is not known with certainty, but is extremely unlikely to be greater than one in a million. It may also be as low as zero. The lifetime risk of developing invasive cancer in the exposed offspring would be less than 43.4801% in a male and 38.3401% in a female. Since the spontaneous risks in unexposed individuals are not known to that level of accuracy, then any cancer arising from the chest x ray would be so rare as to be undetectable.  http://www.hps.org/publicinformation/ate/q996.html\n\nA chest X-ray is not usually done during pregnancy because the radiation could damage your developing baby (fetus). If a chest X-ray is necessary, a lead apron will be used to shield your baby to decrease exposure to the X-rays. http://www.webmd.com/hw/heart_disease/hw205975.asp\n\nWhen you receive a chest x ray at qualified facility, the exposure of the x rays is to your chest, not to your embryo. The "scatter" that might reach the embryo would be extremely small and would not represent an increased risk for birth defects or miscarriage to your embryo. If you are healthy and young and have no reproductive problems or family history of reproductive problems your risk for birth defects is 3% and for miscarriage, 15%. Neither you nor I can change that risk. Good luck with your pregnancy.  http://www.hps.org/publicinformation/ate/q1327.html\n\nHere is my take on it (and I have thought about it for the last 15 years).  The probability of damaging a fetus, in utero, with a chest x-ray (or any x-ray) is very small.  BUT, how will you feel if something is wrong with your baby at birth?  It very well would be for some other reason, but will you spend the rest of your life wondering if that x-ray caused it?
202015
Call your OB/GYN and see if they recommend you come in to the office before your next scheduled visit.  In the mean time, this is what the experts say:\n\nBreast lumps that are not suspicious have the following characteristics:\n\n1.Freely moveable (cancers tend to invade, and therefore feel stuck to the surrounding tissue). \n2.Painful, which usually means inflammation, not tumor \n3.Vascillations of size (cysts related to milk production will change size with the ups and downs of the hormonal fluctuations. Bad cysts will stay the same size or grow bigger). \n4.Very round-ish. (Malignancies are irregularly shaped.) \n5.Small size (less than a centimeter is small.) \n\nSuspicious breast lumps show the opposite of 1-5 above.\nhttp://www.babyzone.com/features/expertsqa/?QAID=173&ExpertID=1\n\nBreast lumps may occur normally in pregnancy, especially in the third trimester when your breasts are getting ready for lactation. Such masses are typically soft, mobile and occur in both breasts. They may be tender. A tail of breast tissue may extend into the axillae or armpit area. \nBreast cancer is uncommon in pregnancy but it does occur. Approximately one to two percent of breast cancers are diagnosed in pregnancy. The prognosis is similar whether the cancer is diagnosed during pregnancy or at another time.  http://www.ivillage.co.uk/pregnancyandbaby/pregnancy/tri3/qas/0,9583,15_157286,00.html\n\nBy the way, I am a registered mammographer with 15 years experience in the field, and I have never done a mammogram on a pregnant woman.  If a pregnant woman has a suspicious mass, we ALWAYS do an ultrasound instead of a mammogram.  Better safe than sorry when it comes to exposing your baby to radiation.