WHY do antibiotics lack inhibitory activitity against eukaryotic cells such as fungi?
924393
Fungal diseases are treated with anti-fungal meds (fluconazole or other meds ending with -zole, clotrimazole) These meds bind to the sterols in the fungal cell membrane and alter the membranes ability to regulate incoming and outgoing traffic (nutrients and wastes). \n\nAntibiotics are limited in their ability based upon the cell type they are used against. Gram positive bacteria have a thick outer layer of peptidoglycan that is susceptible to antibiotics and therefore treatment is relatively easier. \n\nGram negative bacteria have a thin layer of peptidoglycan with a cell membrane protecting it. In order for antibiotics to work, the cell membrane must be breached. Polymyxin B sulfate is effective against gram negative bacteria as it uses a surfactant (detergent) to penetrate and disrupt the cell membrane. \n\nI hope this helps.
736182
Cephalosporine are a group of antibiotics produced by a marine fungus known as Cephalosporium acremonium . It has an antibacterial properties fight against both gram positive and gram negative bacteria. \n            The nystatin is an anti-fungal agent used in the treatment of nonsystamic fungal infection. It is produced during the fermentation by Streptomyces noursei.
196788
It is used as a fungicide and parasiticide in fish. If you define fungi as bacteria, it does inhibit bacterial growth. There are several parasites that affect fish and the compound is used to kill the parasites at low levels.
1167762
Because fungus grows very slowly, and most of the things that they use to treat it kill it by not letting it reproduce.  So if it reproduces slowly, it takes a long time to treat.
554968
the bacteria that are resistant to antibiotics have adapted to their environment in such a way that they are immune to the antibiotics that threaten them.\n\nif most bacteria adapted to antibiotics then many people would die. it all depends on how strong our own immune system is and how quickly an immune response occurs. bottom line: antibiotics would be useless and we will be forced to fight off infections with our own immune system.
845690
No it is antifugal not antibiotic.  I have not heard of it affecting the pill effectiveness but you should ask your pharmacist to be on the safe side as he will have an answer.
241963
When an infection enters your body your immune system increases the white blood cell count which controls the spread of the bacterial or virus.Your temperature rises to "fry" the infection.Antibiotics don't actually destroy bacteria,they prevent them from multiplying,and your immune system does the rest.
1155014
This is a class of proteinaceous chemicals produced by fungi, cyanobacteria, certain marine organisms, etc. that are used defensively to kill bacteria. Some of these chemicals are also active against insects and other small organisms. A few antibiotics have been derived from this class of chemicals.
198655
They block the synthesis of bacteria cell wall\nBeta lactam (contain a ring- beta lactam ring) example are penicillin, cephalosporin, carbapenems\n\n\nSome bacteria now secrete beta lactamase- which stops the beta lactam from working.\n\nHowever, in such infectional bacteria, there are beta lactamase inhibitor that stop the beta lactamase from working. Example: Sulbactam.
888380
You have to have growth to measure the zone. When you put the antibiotic disc on the plate, it creates a gradient of antibiotic concentration in the agar. The growth has to occur to show you what the lethal concentration is. Without any growth, you can do nothing with it. You may want to consider doing it again at 35C instead of 37C. That temperature might be too much for the organism (it does grow on skin usually, so it may prefer a slightly lower temp than body temp). \n\nAs for the concentration, it depends on which antibiotic you are testing. Each antibiotic has a slightly different diameter for sensitive, resistant and intermediate. A table can be found on this high school lab instruction: http://chsweb.lr.k12.nj.us/psidelsky/kirby_bauer_technique.htm
79560
If you do a Culture & Sensitivity Lab, it will show on the Sensitivity part of the lab what antibiotics the bacteria is suseptible and resistant to.  For example, I recently came across a patient with a VRE or Vancomycin Resistant Enterococci, and the only antibiotic it was still suseptible to was Tetracycline.... yes Tetracycline
87591
ringworm is a fungal infection. DO NOT take antibiotics, it won't have an effect, antibiotics only kill bacteria and thats not the case here. Over the counter meds are OK, but if you want a bigger dose and strength of medication depending on the severity of your disease, see a doctor.
810090
Penicillin affects the cell wall of prokaryotes.  Human cells are eukaryotes and do not have cell walls.  Actually, penicillin affects the prokaryote's ability to form the peptidoglycans that make up their cell walls.  Eukaryotic cells (human and any other animal cells) don't contain peptidoglycans.
490824
hi my name is Geeth Prajwal from India i hope this will help you\n\n\n\nIn order to be useful in treating human infections, antibiotics must selectively target bacteria for eradication and not the cells of its human host. Indeed, modern antibiotics act either on processes that are unique to bacteria--such as the synthesis of cell walls or folic acid--or on bacterium-specific targets within processes that are common to both bacterium and human cells, including protein or DNA replication. Following are some examples. \n\nMost bacteria produce a cell wall that is composed partly of a macromolecule called peptidoglycan, itself made up of amino sugars and short peptides. Human cells do not make or need peptidoglycan. Penicillin, one of the first antibiotics to be used widely, prevents the final cross-linking step, or transpeptidation, in assembly of this macromolecule. The result is a very fragile cell wall that bursts, killing the bacterium. No harm comes to the human host because penicillin does not inhibit any biochemical process that goes on within us. \n\nBacteria can also be selectively eradicated by targeting their metabolic pathways. Sulfonamides, such as sulfamethoxazole, are similar in structure to para-aminobenzoic acid, a compound critical for synthesis of folic acid. All cells require folic acid and it can diffuse easily into human cells. But the vitamin cannot enter bacterial cells and thus bacteria must make their own. The sulfa drugs such as sulfonamides inhibit a critical enzyme--dihydropteroate synthase--in this process. Once the process is stopped, the bacteria can no longer grow. \n\nAnother kind of antibiotic--tetracycline--also inhibits bacterial growth by stopping protein synthesis. Both bacteria and humans carry out protein synthesis on structures called ribosomes. Tetracycline can cross the membranes of bacteria and accumulate in high concentrations in the cytoplasm. Tetracycline then binds to a single site on the ribosome--the 30S (smaller) ribosomal subunit--and blocks a key RNA interaction, which shuts off the lengthening protein chain. In human cells, however, tetracycline does not accumulate in sufficient concentrations to stop protein synthesis. \n\nSimilarly, DNA replication must occur in both bacteria and human cells. The process is sufficiently different in each that antibiotics such as ciprofloxacin--a fluoroquinolone notable for its activity against the anthrax bacillus--can specifically target an enzyme called DNA gyrase in bacteria. This enzyme relaxes tightly wound chromosomal DNA, thereby allowing DNA replication to proceed. But this antibiotic does not affect the DNA gyrases of humans and thus, again, bacteria die while the host remains unharmed. \n\nMany other compounds can kill both bacterial and human cells. It is the selective action of antibiotics against bacteria that make them useful in the treatment of infections while at the same time allowing the host to live another day.
280912
Antibiotics are so successful because they exploit differences in physiology between bacterial and human cells. They interfere with biochemical processes which bacteria have, but not humans, e.g. construction of bacterial cell walls.\nViruses do not have the structures and biochemical processes the antibiotics interfere with, so you throw a ton of antibiotics on them and they won't care.
518461
Antibiotics will not work on viral infections, because viruses are not alive and the word ANTI-BIO-TIC means anti-living thing. That's why they work on bacterial infections- bacteria are organisms. \nWhat’s the harm in taking antibiotics\nanytime? Using antibiotics when they are\nnot needed causes some bacteria to become\nresistant to the antibiotic.\nThese resistant bacteria are stronger and\nharder to kill. They can stay in your body\nand can cause severe illnesses that cannot be\ncured with antibiotic medicines. A cure for\nresistant bacteria may require stronger\ntreatment – and possibly a stay in the hospital.\n\nUsing antibiotics for a virus:\n• Will NOT cure the infection\n• Will NOT help you feel better\n• Will NOT keep others from catching\nyour illness
479160
Your question confuses me.\n\nAfter awhile, some species can become immune to pesticides, and therefore cause them to be uneffective, just like if you take too much medicine too often, bacteria can become immune to it and it will not help you get better.