When are people most likely to experience an increase in the number and size of their fat cells?
923360
The size of fat cells increases and decreases as we add / lose weight BUT unless we get to the stage when the cells are absolutely "full as an egg" then the body does not actually make MORE fat cells.\n\nSo...\n\nIncrease in number:  when first developing in the womb and when continually gaining weight without end.\n\nIncrease / decrease in size: all the time as we lose/gain weight.\n\n\nThis is why it helps to lose as much weight as possible before having liposuction, as the fat cells are moreved they are "gone for good" unless you eat to great excess - in which case the body will then make new fat cells to replace the ones you vaccumed out.
260233
No.\n\nType 1 diabetes is an auto-immune disease, like some kinds of arthritis or lupus. It requires an inherited susceptibility (traced to certain kinds of HLA antigens), and a trigger. the trigger is usually infection from any of several things, commonly viruses. German measles is one, as are several members of the Coxsackie virus family. During such an infection, the immune system 'learns' to attack cells with certain surface markers, and beta cells have such markers. At least that's the current best idea of what ususally happens. The beta cells get killed (having the wrong markers) and that ends your internal insulin production. Food has nothing to do with it. \n\nType 2 diabetes is more complex. It is strongly inherited, but is also influenced by environment. Those carrying more weight than they should, and the elderly, are more likely to get it. Hence its older names: obesity-related and adult-onset diabetes. It has recently been discovered that fat tissue, especially fat tissue around the abdominal organs (but not on thighs or hips or chins or ...) produce several hormones, just like the endocrine glands. Some of those hormones affect other cells, and one of them makes them  more resistant to insulin. That is, when insulin is present, it's harder for those cells to take up glucose from the blood. This is insulin resistance and it's at the heart of Type 2 diabetes. Some can be treated with diet, exercise, and supervision; some require all that and oral medications as well; some require insulin, perhaps in addition to an oral medication. \n\nObiously, it's not only sugar which can cause fat like this. Overeating anything, perhaps especially fats, can cause weight gain. Ther's nothing special about weight gain from sugar as opposed to weight from the fat in meats. \nAnyone who eats enough to become a little thick here and there has increased their chance of getting Type 2. Lack of exercise seems to be significant as well. So, whether it's sugar or anything else that you eat too much of, you can increase your chance of getting Type 2. \n\nThe only direct effect of sugar is a speculative one. In the extreme pure sugar (or sugar in solution, like a soft drink) will go into the bloodstream very quickly. This will cause a rapid rise in blood glucose level, and perhaps to a high spike in that level. There is some speculation that too many cases of such rapid spikes causes damage to beta cells in the pancreas or to other cells, in such a way as to increase the chance of developing Type 2 diabetes. Thus far, there only suspicions along this line as an experimental study to test this prediction would be difficult to design and carry out. Not to mention expensive. No drug company will finance such a study as there is no prospect of a salable drug resulting. \n\nIt's probably best to avoid 'empty calories' in any case. The classic examples are soft drinks which are basically nothing but flavored sugar water. Check the nutrient label the next time you see a soft drink bottle.
1176851
Generally speaking, men tend to have more muscle mass and women a higher percentage of body fat.  Muscle generates more heat than fat.
588961
it increases because your body burns more calories to ensure constant supply of energy
392659
It depends, it changes among the part of the body, diet, race, etc, etc
758922
Are you perhaps at your optimal weight now?
49056
from what I learned in my anatomy class, when you gain fat cells you never lose them. They shrink when you lose weight. Thats why overweight people have to stick with a healthy lifestyle after they lose a bunch of weight because its so easy to enlarge those fat cells again if they go back to bad eating habits.
214965
Questions about fat burning and spot toning/reducing are our most popular question. The short answer is that you cannot spot reduce, and the way to burn fat is through aerobic exercise, which burns lots of calories; resistance exercise, which builds muscle (muscle is the engine that burns calories and maintains your metabolic rate); and then watch your caloric intake. \n\n1. There is a genetic factor that determines where people accumulate fat. Women tend to accumulate it in their hips, buttocks, and thighs, and men tend to accumulate it in their abdomen. The reasons for the differences between sexes have not been identified. Some people accumulate more fat than others, and the reasons for that have not been fully identified either, although there are theories. \n\n2. The fat that accumulates on the hips, thighs, and buttocks, although perhaps not cosmetically appealing, is not dangerous for your health. In fact, there is some evidence that it is actually good for your health. The opposite is true for abdominal fat. That fat has been implicated in heart disease, diabetes, and other health problems. Men with a large pot belly are therefore at increased health risk, whereas women with large hips or thighs are not necessarily at risk, at least not from the fat on their lower extremities. \n\n3. Fat, no matter where it is on the body, belongs to the entire body, so you can't spot reduce, i.e., you can't do sit-ups and lose abdominal fat, and you can't do leg raises and lose thigh fat. \n\n4. Fat is stored in special fat cells called adipocytes located all over the body. You have anywhere from 25 billion to 275 billion adipocytes. The average individual has around 30-35 billion. These adipocytes store fat and they release fat. When they release fat, the adipocyte gets smaller, and when they store fat, the adipocyte gets larger, just like a balloon that you fill with air or release air from. Contrary to popular belief, adipocytes do not divide when they get too big. Instead, what happens is that as an adipocyte absorbs excess fat and increases in size to approximately 15-20 microns (the diameter of a human hair is 100 microns), it sends a biochemical signal to adjacent adipocyte precursor cells called preadipocytes to absorb fat and grow larger. These preadipocytes then become fully mature adipocytes, and as a result, the individual gets fatter. During childhood and into puberty, both the number of mature adipocytes (hyperplasia) and the size of the adipocyte increases. It is believed by many scientists that the number of adipocytes stays fairy stable after adolescence and instead of an increase in the number of adipocytes during adulthood, the mature adipocytes enlarge to increase body fat. However, there is some recent evidence to suggest that the number of mature adipocytes can also increase during adulthood. In any case, what is certain is that excess caloric intake leads to increases in body fat, either through hyperplasia or through enlargement of the adipocyte. \n\nIt should be noted that preadipocytes develop from special cells in the body, and although genes control proteins that control preadipocyte function and development, the process is extremely complex and not well understood, but scientists are busy studying it. \n\nOne other point on this subject. Adipocytes do not disappear when they get smaller. They shrink only to a certain size, and then they just hang around as very tiny adipocytes, and they can always get large again. The only way to get rid of them totally is through liposuction. \n\n5. Adipocytes get large by feeding them. If you eat more calories than you burn, some of the excess carbohydrate will be stored as sugar, or glucose, in the muscles (called glycogen), and the rest of the excess will be stored as fat in the fat cells. If you continue to eat more than you burn, you continue to feed the adipocytes with fat and you get fatter. \n\n6. When you exercise, the adipocytes release fat into the
902795
BMI can be deceptive. If someone is very musclular their BMI may be high, but that's good for them. \n\nConversely, people with poor muscle tone can be "normal" when in fact they have too much fat and not enough lean. \n\nCholesterol is also determined, not only by genetics, but by the food we eat. Cholesterol in food has little effect in most, but high sugar intake can make your numbers go up dramatically. Trans fats, smoking, lack of exercise also help raise your cholesterol profile.
245056
1. Eat more calories than you burn.\n2. Gland problems can make one fat.
937833
They trigger the body to mature, grow breasts, shape changes, hair appears, etc.
183492
Exercise and diet have a major impact.
344957
have a baby , 2nd after 10-15 years women get extra fat to their bodies , as of their nature , watch ur mom ,and grand mom , so dont rush for extra fat
209209
Some people (like your friend) have a very high matabolism. Wich means that their bodies can convert more fat/sugars into energy and burn them faster than people with lower or slower matabolisms.
370356
you are building more muscle mass which actually weighs more than fat
349137
No you are not fat, it's just that some people when they are smaller have more wait, but as soon as you begin to grow older and taller then your weight and height will even it. It's not that your fat , it's just that you have matured at an early stage but soon you will be as small as your friends as long as you continue to exercise and eat properly.
876189
I believe that they show up more after you have lost weight.  When you are gaining weight, the skin is taut.  After losing weight, the skin is loose and flabby.