When people overdose from cocaine, what happens? Is it a heart attack, or what...?
340770
Crack and cocaine users have died from overdose. High doses can raise the body's temperature, cause convulsions and respiratory arrest. Risk of overdosing increases if crack is mixed with heroin, barbiturates or alcohol.\nCocaine is bad news for anybody with high blood pressure or a heart condition. Perfectly fit, young people can have a fit or heart attack after taking too much coke. \nThose who get into coke often find they begin to crave it more and more. \nUsing it a lot makes people feel depressed and run down.\nToo much sniffing coke and you're sneezing lumps out of your nose into a hanky. \nPeople who use crack or coke regularly often develop serious problems with anxiety and paranoia. It's a known cause of panic attacks. \nBecause the effects wear off so quickly, cocaine and crack are expensive drugs. A cocaine habit can seriously damage your wallet. \nVery large doses can cause death from heart or respiratory problems. You may not know you have a pre-existing heart condition.\nLarge or frequent use of coke tends to knock sexual desire on the head.\nIf there have been previous mental health problems coke could bring those problems to the surface again. If a close relative has had mental health problems there might also be an increased risk in some users.\nInjecting any drug can cause vein damage, ulcers and gangrene. Dirty or shared needles and other injecting works can help the spread of HIV and hepatitis.\nIt's easier to overdose injecting. Cocaine is a local anaesthetic and it deadens pain at the injection site. This makes it harder for injectors to notice the damage they may be doing. \nUsing alcohol and cocaine together can be deadly.\nInjecting a mixture of cocaine and heroin, known as a 'Speedball' is one of the most dangerous cocktails you can put in a human body. It is also potentially deadly.\nTaking coke when you're pregnant can damage your baby. Coke causes miscarriage, premature labour and smaller babies and may cause congenital abnormalities. Babies born to mothers who keep using throughout their pregnancy show withdrawal syndrome.
1151068
The drug phentermine is a dangerous medication in high doses.  I would suggest you check with your doctor before splitting pills in half and also be careful of the time of day you take it.\n\nSymptoms of a phentermine overdose include restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures.
35832
He died of a heart attack, his weakened coronary condition was both caused and exacerbated by years of (past)drug and alcohol(ab)use.\nViva La Raza!
745596
According to the following website, it depends on the form of cocaine being produced, and looks like some really nasty chemicals are involved (sulfuric acid, kerosene, benzene, ammonia, etc...). Yuck.\n\nhttp://en.wikipedia.org/wiki/Cocaine
732342
I am not sure if you mean - can you administer a substance to yourself that would induce a cardiac arrest OR by thinking about it real hard, being in emotional distress, or by performing some extraordinary physical activity, could you induce cardiac arrest?\n\nYou could potentially administer any number of substances that would cause the heart to go into an arrhythmia, or go too fast, or stop...all potentially precipitating an arrest.  This could be done by mouth or by IV or via electricity.  \n\nIn terms of making it happen by running too hard or having an emotional event.  In short, you would need to have some heart disease there already in order for this to happen.  Therefore if you had a young healthy heart, it would be virtually impossible to induce a cardiac arrest by anything you did or by any amount of emotional distress.
1106098
DONT THINK OF DOING IT PLEASE!\nWhat's so bad about cocaine \nFIRST COCAINE LEADS YOU TO:\n Sudden heart attack \nDeath \nLoss of sexual function \nAddiction, even after occasional use AND even after one try \nBrain seizures \nAddiction, \nIrregular heartbeat \nDepression \nStroke \nViolent actions
614098
If you have overdosed on this medication, you need to go to the ER right away.  Symptoms of a loratadine overdose include headache, drowsiness, irregular heartbeat, nausea, and vomiting.
1171732
Acute\nCocaine is a potent central nervous system stimulant. Its effects can last from 20 minutes to several hours, depending upon the dosage of cocaine taken, purity, and method of administration.\n\nThe initial signs of stimulation are hyperactivity, restlessness, increased blood pressure, increased heart rate and euphoria. The euphoria is sometimes followed by feelings of discomfort and depression and a craving to experience the drug again. Side effects can include twitching, paranoia, and inability to get an erection, which usually increases with frequent usage.\n\nWith excessive dosage the drug can produce hallucinations, paranoid delusions, tachycardia, itching, and formication.\n\nOverdose causes tachyarrhythmias and a marked elevation of blood pressure. These can be life-threatening, especially if the user has existing cardiac problems.\n\nThe LD50 of cocaine when administered to mice is 95.1 mg/kg. [13] Toxicity results in seizures, followed by respiratory and circulatory depression of medullar origin. This may lead to death from respiratory failure, stroke, cerebral hemorrhage, or heart-failure. Cocaine is also highly pyrogenic, because the stimulation and increased muscular activity cause greater heat production. Heat loss is inhibited by the intense vasoconstriction. Cocaine-induced hyperthermia may cause muscle cell destruction and myoglobinuria resulting in renal failure. There is no specific antidote for cocaine overdose.\n\nCocaine's primary acute effect on brain chemistry is to raise the amount of dopamine and serotonin in the nucleus accumbens (the pleasure center in the brain); this effect ceases, due to metabolism of cocaine to inactive compounds and particularly due to the depletion of the transmitter resources (tachyphylaxis). This can be experienced acutely as feelings of depression, as a "crash" after the initial high. Further mechanisms occur in chronic cocaine use.\n\n[edit]\nChronic\nWith chronic cocaine intake, brain cells functionally adapt (respond) to strong imbalances of transmitter levels in order to compensate extremes. So receptors disappear from or reappear on the cell surface, resulting more or less in an "off" or "working mode" respectively, or they change their susceptibility for binding partners (ligands) – mechanisms called down-/upregulation. Chronic cocaine use leads to a DAT upregulation, further contributing to depressed mood states. Finally, a loss of vesicular monoamine transporters appears to indicate a long term damage of dopamine neurons.\n\nAll these effects contribute to the rise in an abuser's tolerance thus requiring a larger dosage to achieve the same effect. The lack of normal amounts of serotonin and dopamine in the brain is the cause of the dysphoria and depression felt after the initial high. The diagnostic criteria for cocaine withdrawal is characterized by a dysphoric mood, fatigue, unpleasant dreams, insomnia or hypersomnia, E.D., increased appetite, psychomotor retardation or agitation, and anxiety.\n\nCocaine abuse also has multiple physical health consequences. It is associated with a lifetime risk of heart attack that is seven times that of non-users. During the hour after cocaine is used, heart attack risk rises 24-fold.\n\nSide effects from chronic smoking of cocaine include chest pain, lung trauma, shortness of breath, sore throat, hoarse voice, dyspnea, and an aching, flu-like syndrome. A common misconception is that the smoking of cocaine breaks down tooth enamel and causes tooth decay. Although this is not true, the lifestyle of frequent cocaine users may include poor dental hygiene, which often results in tooth decay. In addition, cocaine often causes involuntary tooth grinding, known as bruxism, which can deteriorate tooth enamel and lead to gingivitis[citation needed].\n\nChronic intranasal usage can degrade the cartilage separating the nostrils (the septum nasi), leading eventually to its complete disappearance.
884065
He had a heart attack while brushing his teeth in his hotel room one night.  His heart was weakened from several years of cocaine and steroid abuse.\n\nHe had gone to rehab in 2002 and cleaned up and gotten off drugs and alcohol completely, but the years that he did use drugs took a toll on his heart, leading up to the heart attack years later.  He was clean for 3 years when he died.
501001
I WAS ADDICTED TO COCAINE AND OTHER DRUGS FOR 3 YEARS. IT STARTED WITH A LINE HERE AND THERE AND I ENDED UP IN A "BLIZZARD" SO TO SPEAK. I WAS WORKING TO BUY COCAINE AND OTHER DRUGS. THROUGHOUT THE 2 YEARS I HAVE SEEN PEOPLE I CARE ABOUT DIE; ON FRIEND HAVE A HEART ATTACK AT 22 YEARS OLD. I MYSELF HAVE SEEN DEATH 3 TIMES AND LIVED TO TALK ABOUT IT. I TELL YOU THIS WITH ALL SERIOUSNESS I RUINED MY LIFE. I LOST MY FAMILY, ALL MY FRIENDS (EXCEPT MY FELLOW ADDICTS) EVERYTHING THAT EVER MEANT SOMETHING TO ME I LET SLIP AWAY JUST SO I COULD BE HIGH. I AM PROUD TO SAY I HAVE BEEN CLEAN FOR 10 MONTHS NOW WITH NO RELAPSE. I AM STILL TEMPTED BY IT TO THIS DAY; I WAKE UP IN THE MIDDLE OF THE NIGHT SWEATING. SOME OF THE EFFECTS I STILL DEAL WITH ARE RAISED HEART RATE, ITCHING SKIN, PARANOIA, HALLUCINATIONS, THOUGHTS OF CONSPIRACY, TROUBLE BREATHING, NOSE BLEEDS, LACK OF BOTH LONG AND SHORT TERM MEMORY ... AND SO ON. THIS IS NOT A DRUG YOU CAN JUST DO SOCIALLY THAT’S WHAT I THOUGHT AND THEN MY LIFE WENT DOWN HILL FROM THERE. I HAVE LIVED ON THE STREET, MOVED FROM HOUSE TO HOUSE, GONE WEEKS WITHOUT EATING OR SLEEPING. I HAVE DEVELOPED A SLEEPING DISORDER BECAUSE OF MY USE WHEN I DO SLEEP I WAKE UP SCARED. I AM ONLY 21 YEARS OLD RIGHT NOW BUT HAVE LIVED ENOUGH BAD EXPERIENCES TO LAST A LIFETIME. I HAVE A WONDERFUL BOYFRIEND WHO HAS SEEN ME THROUGH MY REHABILITATION AND A BEAUTIFUL BABY GIRL TO WATCH GROW UP. I WOULD SAY TO YOU LEARN FROM MY STORY ON ANYONE ELSE WHO TELLS YOU WHAT IT IS LIKE, IT'S NOT WORTH IT. I YOU LOVE EVEN ONE PERSON IN THIS WORLD DON'T DO IT. YOU WILL GO TO HELL AND BACK IF YOU’RE LUCKY AND DON'T DIE. I REGRET NOT TAKING ANYONE'S ADVICE BEFORE I BECAME ADDICTED SO PLEASE TAKE ALL THIS INFORMATION TO HEART AND SAVE YOURSELF BEFORE YOU ARE UNABLE TO BE SAVED.
1142305
the main side effect is tachycardia which is rapid heartbeat. Go to http://www.nlm.nih.gov/medlineplus/ency/article/002636.htm#Symptoms for advice if you have such a patient, and as soon as possible. That website is a national N.I.H. (U.S.A.), poison information site.\nYou should answers for the following questions before the contact.\nthe patient's age, weight, and condition \nthe name of the product (ingredients and strengths if known) \nthe time it was swallowed \nthe amount swallowed \nAlso contact the local poison control center.\nGood luck
253627
overdose causes nervousness ,shakes ,insomnia ,rapid heart beat,irregular heartbeat,
659631
Well there are many different ways to die. One symptom of a heart attack is nausea and possible vomitting and a bowel movement.
941242
cocaine?  that's bad!!
22679
read here\nhttp://www.drug-overdose.com/codeine.htm
874634
heartattack\ntoo many drugs and alcohol
1142635
According to doctors, alcohol increases the impact of cocaine sharply. Dr N P Singh, professor of medicine at Maulana Azad Medical College, said, “Cocaine acts as a vaso-constrictor,” which means that it constricts the blood vessels, making blood flow difficult. \n\nIn case of excess consumption of the drug, or an overdose, the person could suffer ‘‘sudden heart attack-like situation, respiratory failure, and in the worst case, even sudden death.’’ Singh said ‘‘with alcohol, the metabolic profile of the drug gets altered and its effect is a lot more intense and long-lasting.’’ But he added that the alcohol content in champagne is low.