What disease can result when pancreas doesn't make enough insulin?
349904
Insufficient insulin levels lead to hyperglycemia, which is an abnormally high blood glucose (sugar) level. The overall medical condition is called diabetes.\n\nType I diabetes occurs when your immune system destroys the Islets of Langerhans in the pancreas, which produce insulin.\n\nType II diabetes occurs when the pancreas produces the correct amount of insulin, but either the insulin is defective or the cells that require insulin for glucose uptake become resistant to insulin. \n\nTherefore, if your pancreas isn't making ENOUGH insulin, it is probably due to Type I diabetes.
974679
Because that's where insulin is produced, and not all Pancreas Cells make insulin. Insulin is made and secreted by the beta cells of the pancreatic islets, small islands of endocrine cells in the pancreas.
783272
Alternative Names:\n\nNoninsulin-dependent diabetes mellitus; Diabetes - type 2\n\n\nCauses, incidence, and risk factors:\n\nDiabetes is caused by a problem in the way your body makes or uses insulin. Insulin is needed to move glucose (blood sugar) into cells, where it is used for energy.\n\nIf glucose does not get into the cells, the body cannot use it for energy. Too much glucose will then remain in the blood, causing the symptoms of diabetes.\n\nThere are several types of diabetes. This article focuses on Type 2, which is usually accompanied by obesity and insulin resistance. \n\nInsulin resistance means that insulin produced by your pancreas cannot get inside fat and muscle cells to produce energy. Since the cells are not getting the insulin they need, the pancreas produces more and more. Over time, abnormally high levels of sugar build up in the blood. This is called hyperglycemia. Many people with insulin resistance have hyperglycemia and high blood insulin levels at the same time. People who are overweight have a higher risk of insulin resistance, because fat interferes with the body's ability to use insulin.\n\nType 2 diabetes usually occurs gradually. Most people with the disease are overweight at the time of diagnosis. However, Type 2 diabetes can also develop in those who are thin, especially the elderly.\n\nFamily history and genetics play a large role in type 2 diabetes. Low activity level, poor diet, and excess body weight (especially around the waist) significantly increase your risk for type 2 diabetes.\n\nOther risk factors include:\n\nRace/ethnicity (African-Americans, Hispanic-Americans, and Native Americans all have high rates of diabetes)\nAge greater than 45 years\nPreviously identified impaired glucose tolerance by your doctor\nHigh blood pressure\nHDL cholesterol of less than 35mg/dL or triglyceride level of greater than 250mg/dL\nHistory of gestational diabetes
1050468
Diabetes. Low Blood Pressure, Lots of stuff See a Dr.
596185
among other things hypoglycemia.......(low blood sugar, from not eating enough , exercise too much , too much ensulin)......\n\nfrom links below--\nOther Causes of Hypoglycemia\n\nHypoglycemia in people who do not have diabetes is far less common than once believed. However, it can occur in some people under certain conditions such as early pregnancy, prolonged fasting, and long periods of strenuous exercise. People on beta blocker medications who exercise are at higher risk of hypoglycemia, and aspirin can induce hypoglycemia in some children. Drinking alcohol can cause blood sugar to drop in some sensitive individuals, and hypoglycemia has been well documented in chronic alcoholics and binge drinkers. Eating unripe ackee fruit from Jamaica is a rare cause of low blood sugar.\n\nSymptoms of mild low blood sugar usually develop when blood sugar falls below 60 to 65 mg/dL and may include:\n\nNausea. \nExtreme hunger. \nFeeling nervous or jittery. \nCold, clammy, wet skin; excessive sweating not caused by exercise. \nA rapid heartbeat (tachycardia). \nNumbness or tingling of the fingertips or lips. \nTrembling. \n\n\nFasting low blood sugar (hypoglycemia). This type occurs when you have not eaten for many hours, such as overnight. It is frequently associated with having too much insulin in the blood, some medications, alcohol use, hereditary problems with the metabolizing of carbohydrates, and other health conditions. \nNonfasting low blood sugar (also called reactive or postprandial hypoglycemia). This type develops within 3 to 4 hours after eating. It can be caused by hereditary enzyme deficiencies such as galactosemia or by surgery to remove all or part of the stomach. Sometimes the cause is unknown. Nonfasting hypoglycemia within 1 to 2 hours after a meal (alimentary hypoglycemia) can occur if stomach contents empty into the intestines too rapidly.
540980
in layman's terms:  the pancreas produces insulin (among other functions), the insulin helps the body break down sugars so they can be used for energy.  With no insulin to break down sugar, the body has to break down fats and proteins for energy.  That means the sugars stay in the bloodstream causing high blood sugar.  That can lead to a whole bunch of problems.
75121
i dont think that the pancreas enlarged coz for a person with Type II Diabetes,the pancreas works properly.Only the cells lost their sensitivity to the hormone that is secreted by the pancreas (insulin)
773851
There is no known cause for PCOS. The only link between that and diabetes is insulin resistance.
387700
Many reasons but all of them ultimately result in a non-responsiveness to hormones in the body i.e. an imbalance of hormone relative to the substance or process the hormone is supposed to regulate.\n\nExample:  diabetes mellitus is a disorder resulting from damage to, or simple absence of, the beta cells of the pancreas ( although could also be due to lack of insulin receptors throughout the body so that even though insulin is being produced, it can't have en effect since there is nothing to pick it up in the body ).\n\nThis is a much simplified answer!
1003431
Don't be scared.  Insulin levels can change due to stress, environment and among many other things.  Wait to see your doctor and don't fret.
1017892
Diabetes comes in 2 forms....Type 1 which is insulin dependant and occurs in young children and cant be cured.......Its caused by the bodies ammune system attacking the part of the pancreas that makes insulin......The symtoms are thirst, excessive drinking due to the dody trying to rid itself of sugar, lethargy and a general feeling of unwellness......\n\nType 2 diabetes is usually due to incorrect lifestyle and is known to be hereditary......Lack of excercise, bad diet and weight gain are the general cause of this disease......Treatment maybe a change in diet and excercise, some people require tablets and in certain cases may require insulin injections......But if managed properly this is only required in extreme circumstances.....\n\nAs the mother of a child with type 1 diabetes and the relative of parents with type 2 diabetes, i hope this is helpful.....
116934
Time for insulin!  Needing insulin is a natural progression of the disease, and most people with type 2 end up on it eventually.  Diet, exercise and pills are not enough at this point probably.  Talk to your doctor about going on insulin.  It's nothing to be afraid of.
591127
It is difficult to answer this question, as more information is needed...BUT :\nEpisodes of hypoglycaemia can cause large sympathetic outflow, which can sometimes cause people to lose control of their bowels (and bladder). But this would be fairly obvious, as it would always be after a clinical episode of hypoglycaemia.\nInfections can wreak havoc with glucose control, and urinary tract infections can certainly present with tremors and incontinence. Worth checking out. Diabetes makes one more susceptible to infections in general - any signs of skin, foot, lung etc infections?\nIf his diabetes is secondary to chronic pancreatitis, lack of pancreatic enzymes may cause voluminous foul stools, and potentially incontinence (but not urinary incontinence).\nIs there any concerns about dementia, Normal Pressure Hydrocephalus  or Parkinson's disease? \nAny back problems, trauma or spinal compressive symptoms?
160827
Lots of things you should be more explicit, Diabetes type one is a condition that where the pancreas more no insulin and is needed to be injected daily. Diabetes type two is when the pancreas makes little insulin or too much but the receptors in the cells don't match up so the insulin can't get in to bring the sugar down. Complications range from amputaions to blindness.
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=========\ninterference with insulin production \n\nA sufficiently serious infection of the pancreas could cause enough destruction to induce Type 1 diabetes directly (destroyed beta cells, no insulin production). And, since Type 1 is most commonly an auto-immune disease in which the immune system has attacked and destroyed the insulin producing beta cells, anything which can start this misdirected response will do. Generally, it's thought  that it is viral infections which are mostly at fault: German measles, several of the Coxsackie family viruses, etc. It is probably not impossible that some bacterial infection could do more or less the same thing, but it's not generally seen clinically. \n\n=====================\nassociated issues\n\nThe increased glucose levels in the blood of diabetics are a help to many bacteria, so it's likely they will have an easier time being active in diabetics. And, diabetics very often have impaired  circulation which helps some bacterial infections since the immune system has reduced access to them. If this is bad enough, it can lead to the too common infections which are the cause of gangrene and of amputation. And, finally, there are some reports that diabetics' immune systems are somewhat less effective than non-diabetics'. But none of these are, quite, 'increased development of diabetes' due to bacterial infections.
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type 1 is caused by the simple fact that your pancreas does not secrete insulin.  type 2 is when your pancreas does secrete some insulin but your body is not able to use it. Type 1 is not related to the amount of sugar you eat. It's said to be autoimmune. Type 2 is usally caused by obesity.
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Insulin.  In Type 1 diabetes mellitus, the cells of the pancreas produce little or no insulin to regulate blood glucose level appropriately.  It can occur at any age, but usually starts in people younger than 30.  It also has a strong genetic link.