what is the procedure for safe administration of cytotoxic drugs?
343126
IT really depends on the drug. \nU need to follow the instructions that come with each drug. Some cytotoxic drugs can be taken by mouth (patienhts usually think these ones are less harmfull to them) or intravenously. The most important thing too is to take the right dose and the right time as too much harms the paient too much, too little doesn't have enough effect on the disease (usually tumour).
317452
It depends on the protocol the child is on.  My daughter was dx with ALL last year and she is enrolled in a study at St. Jude.  She takes several different kind of chemo drugs a day and several more over a course of weeks and months.  Many children will have several BMA's, CBC's, MRI's, CT scans, and many other tests depending on their type of ALL and how far into their treatment they are.  You can check out the protocol for ALL at St. Jude by going to their web page.
373095
If you are asking if a person can receive both at the same time, yes. My dad is taking both treatments right now. I can't say for sure that he takes both in the same day, though. His is for lung cancer.
23484
To be honest, chemotherapy is not a cancer treatment.  Here is the situation.  Chemo can take care of the problem right away, but the doctor always says that, some can live an extended 2 years, or 3 years.  And some die right away from the chemicals.  This is with late stages of cancer.  Now, for early stages, it helps the problem but your health is deteriorated. They say that chemo affects the cancer and your normal body cells.  How many people you know, who have had late stages of cancer, and lived through it pass 5 yours with chemo therapy?  I bet you that you have never even heard of it.  Even if someone has, how many people is that compared to that masses?  The problem with other medicines is that the pharmaceautical companies cannot control that product.  What if it was tree bark say for instance.  How many people do you know will buy the pills if they can just walk up to any tree and bite a piece off to save themselves?  See?  So, USA doctors are familiar with these remedies, but they do not talk about it.  Try asking your doctor about green algae, or cesium chloride, or paw paw, etc etc.  Then they start to talk.  Otherwise, they wont say a word.  And if you dont know, how can you ask?  So, the doctors lips are sealed tight.  The individual doctors on the other hand are sometimes scared to talk about it.  It is because, if they open their mouths, they would be facing the whole medical community.  Alot of them go into the medical field to help people, and some go in it for money.  But, the top ranking ones in control are all in it for money.  If not, they would have never gotten their position.  I do not suggest you go with chemo therapy.  You can look up some alternative medicine to cancer and they are all over the place on the net.  The best ranked one is cesium chloride, paw paw, and along with others.  Some health websites even have a place where you can go and tell them your stage of cancer and which type of cancer, and they will sell you a package based on your individual problem.  There are also some doctors scattered all over the USA who specialize in cancer.  You never hear about them right?  Well, they wont be bothered by the medical community if they do a small operation without much advertising.  But, they all report about 90% survival rates on cancers that regular cancer doctors give up on.  And if that doctor didnt give up, do you expect to live anyways?  No.  I speak out to you because I dont want you to die like the two of my friends who have already died.  Certain doctors even said that they could cure it with 80% survival rate.  But, I didnt have the money to help them.  So, I am speaking out in hopes that nothing happens to you and you survive.  Regardless of your stage of cancer.  Cesium chloride is what works best.  Look it up, its everywhere.  Even oxygen drops help.  You can use them both at the same time.  The thing is with these alternatives is that, some of them make you feel extremely bad at the beginning, but after a while you get used to it, and then you are gone with the cancer before you know it.  So dont feel discouraged.  Oxygen drops keep cancer from growing because your body can live with more oxygen.  As a matter of fact, it helps circulate your blood.  Cancer cannot live at the sight of oxygen.  It has been said that not enough oxygen is what causes cancer. I dont know what the cause is, because there are many causes.  But, cesium chloride and oxygen drops will take care of it.  And one more thing, some of these remedies cannot be sold as a cancer treatment.  So, they are sold as vitamins.  But, in their website, they are allowed to say what it cures.  But, their labels cannot say a word about cancer.  So, you should start in the vitamin section of the internet.  Good luck my friend.
195810
Well to lyse the cell use the freeze thaw method and use a high salt solution to lyse the cell and salt out the cytosolic proteins!
441605
Try this site out...\nhttp://www.bartelldrugs.com/cpdrugidentifier/default.jsp
1151600
Chemotherapies can be given through I.V. or in oral form.  Chemotherapy kills fast growing/dividing cells.  That's why many will cause a persons hair to fall out.  Every chemo treatment is given differently, because each drug affects people differently.  \n\nI had Hodgkin's Disease and was on a regimen known as ABVD (Adriamycin, Bleomycin, Vinblastine, DTIC).  I didn't have horrible side effects, but some common side effects are:  Low blood counts (white blood cells, hemoglobin, platelets...ect)  fatigue, nausea, hair loss, mouth sores (the chemo can cause the insides of your mouth to "sluff" away leaving sores) constipation, diarreha, anemia, loss or change in taste buds, infertility, weight loss or gain...and the list goes on.  \n\nI also did a set of salvage chemotherapies when my cancer stopped responding to the ABVD.  This was a combination of Gemzar, Navelbine and Doxil.  The side effects were pretty much the same.   \n\nI also went in for "high dose" chemotherapy which was a combination of the drugs:  BCNU, Etoposide, Arc-C and Cytoxin.  Since they were given in "high dose" form they destroyed all of my bone marrow and the blood cells that are created there (white blood cells, hemoglobin and platelets)  In order to give high dose chemos, a person needs to have stem cells or bone marrow waiting to be transplanted back into them.  I had my own stem cells harvested from my blood, it's known as a autologous stem cells transplant.  The cells go back to the bone marrow and start making new bone marrow after the chemo kills pretty much every fast dividing cell in the body.  \n\nEvery cancer has different chemo treatments and every chemo has to be given differently, though many are simply given through I.V.
86297
Direct application of anti-cancer drugs to cancer cells. Being able to scrape the junk that builds up on arteries and leads to heart attacks.\n\nStuff like that.
878625
Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are a chemical substance or an immune cell.\n\nCytotoxicity can be measured by the MTT assay.\n\nAntibody-dependent cell-mediated cytotoxicity (ADCC) describes the cell-killing ability of certain lymphocytes, which requires the target cell being marked by an antibody. Lymphocyte-mediated cytotoxicity, on the other hand, does not have to be mediated by antibodies; nor does complement-dependent cytotoxicity (CDC), which is mediated by the complement system.\n\nThree groups of cytotoxic T lymphocytes are distinguished: antigenic (immunized) T lymphocytes, killer cells, and natural killer cells.\n\n\n\nCD8 (cluster of differentiation 8) is a glycoprotein which serves as a co-receptor that is expressed on the surface of cytotoxic T cells. CD8 consists of an α and a ß chain, which both resemble an immunoglobulin-like domain that is connected to the membrane by a thin stalk. It is attracted to the α3 portion of the Class I MHC molecule. This affinity keeps the T cell receptor of the cytotoxic T cell and the target cell bound closely together during antigen-specific activation. Cytotoxic T cells with CD8 surface protein are called CD8+ T cells.\n\nThionins are a family of peptides found solely in higher plants. Typically, a thionin consists of 45-48 amino acid residues. 6-8 of these are cysteine forming 3-4 disulfide bonds. Some thionins have cytotoxic activity and they are therefore interesting in the development of new drugs against cancer with novel action mechanisms. As of yet, no thionin has ever been developed into an anti-cancer drug.
109566
Be very careful taking products like this.  Have you talked to your doctor?  Do it the safe way, under a doctor's supervision.
108972
Podophyllotoxin solution
507863
Hard to say without more information regarding prior treaments (cisplatin/taxol?) A general rule in cancer treatment with chemotherapies is that the response time between treatments continues to get smaller and smaller (e.g. respond for 6 months, relapse, respond for 3 months, relapse, respond for 1 month...etc).  Good luck.
474976
Hi various routes with examples: probably not comprehensive but I tried!!!\n\n\nOrally: common medication ie aspirin\n\nIntravenously: Many chemotheraoy regimes\n\nTransdermally some anti inflammatories/skin creams\n\nSubcutaneously Some vaccinations\n\nVia the lungs: salbutamol inhalers for asthma\n\nIntra muscularly ie some analgesics\n\nPer rectum some analgesics such as diclofenac\n\nIntra vesical instillation some chemotherapy regimes for bladder cancer are installed in the bladder\n\nEpidural: anaesthesia\n\nVia CNS: Methotrexate as chemotherapy for some tumours in brain, notably lymphomas\n\nIntra peritoneal instillation: some cancer chemotherapy.\n\nIntra arterially/or into the heart: very rarely adrenalin in an absolute emergency in cardiac arrest\n\nAny i've missed anyone????
96576
Cisplatin is the most potent nausea and vomitting inducing Anticancer agent more than oxyplatin. Oxyplatin is not in oral form must be given with leukovorin to reduce neurotoxicity. When giving Oxyplatin, tell patients to avoid cold food or environments.
978083
Hi -\n\nI'm sorry to hear about your brothers GBM.  \n\nCarboplatin has a half-life of 1-2 hours initially, and can be effective for up to 10 days.\nStarting dose is calculated based upon a persons weight, height, and kidney functions.  A typical dose for subjects with no previous treatment is 400mg/m2, at one time.  Dosing may be increased, depending on the severity of the disease, and the patients reaction to treatment.\nAs with most chemotherapy, this drug can suppress your immune system (bone marrow production of white blood cells).  Also, the patient can become thrombocytopenic, and anemic, which is usually temporary.\nIf your brother has a blood test, he might have an increased BUN, and serum creatinine, and liver enzymes may become elevated.  Once treatment ends, all of these symptoms usually cease.\nAs I am sure he knows, he can expect to experience GI upset and vomiting for the first 24 hours after dosing administration.\nCarboplatin is excreted primarily in the urine with 65% of the dose excreted after 12 hours and approximately 70% within 24 hours. \nAll of this information is available on the drug label, or the FDA website.\nHas his doctor mentioned temozolomide?\n\nGood Luck
507189
If you seriously want an answer to your question, along with many other questions about cancer, may I suggest you pay a visit to the website, www.cancertutor.com where you may have to spend several hours, but you'll find answers from numerous reputable and reliable sources. Almost all cancers are completely treatable and curable using safe, effective, and often economical alternatives. At that same site, you'll find out about the immense corruption in the pharmaceutical industry, where cancer is considered to be a "highly profitable commodity", no different than precious metals, gems, petroleum or real estate. Be prepared for a "rude awakening" about the REAL world of medicine!
883987
chemotherapy dosing is a critical issue. If the dose is to low it will not have the desired effect, two high and it will cause more side effects. There are some chemotherapy drugs that have little or no side effects, is that what you are looking for? Ask your oncologist about the risks and benefits of each treatment. They will be able to explain each drug and the probability of side effects