structures of steroid hormone receptor-glucocorticoid,androgen e.t.c.allstructural domains?
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A. If you don't have it yet, download and install Cn3D:\nhttp://www.ncbi.nlm.nih.gov/Structure/CN3D/cn3d.shtml\n\nB. Go to:\nhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=domains\nand search for your domains. They are all there, plus alignments of related ones as one structure. Click and view in Cn3D.
971988
male hormone - androgen
122666
http://www.seedbiology.de/structure.asp
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we love STEROIDS!!!\n\n\nSTEROIDS!!!
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Androgen secretion by adrenals (mainly DHEA and DHEA-S) is but a small part of the array of hormones it produces, the most important one being cortisol and aldosterone.\n\nWhen you say you have low adrenal function, the possible causes can be a deffect in the pituatiry control of the adrenal function and, sorry, you have to see a doctor to resolve the problem, DHEA won't cure your low cortisol or aldo...
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hormones are molecules that act on cells to cause changes in cellular homeostasis.  Steroids are made from cholesterol (such as progesterone, testosterone).  Other horomones such as growth factors are proteins, others are small peptides such as insulin.
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That's sort of a broad request.  Are there any specific types of structures that you are looking for?  I know of a good site that has 3D models of proteins, structures derived from X-ray crystallography studies:\n\nhttp://www.pdb.org/pdb/advSearch.do\n\nJust chose 'structure description' as your 'query type' and enter the name of a protein into the search field.  They have quite an extensive database.\n\nThe Univ of Mass also has links to some other structures (DNA, antibodies, etc).  The images were generated by Chime, a powerful (and unfortunately not free) software program for generating 3D structures.\n\nhttp://www.umass.edu/microbio/rasmol/\n\nHope this helps!
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Androstene, get it at your local supplement store.  (you can't buy at GNC, because it's not approved by the FDA)
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As I explained to your previous question, a steroid is any chemical including the steroid skeleton (see my previous link).  The different steroids have different attachments.  For instance, cholesterol has a long chain of fat attached to it, which is what causes it to collect and block arteries if you have too much of it.\n\nThey shouldn't all be the same anymore than carbon dioxide should be the same as carbon monoxoide.  Different attachments mean different chemical properties.
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If you know that the structure of the hormone is already known, then the SciFinder is best.  If you are talking about original research, then you must get your hands on enough of the pure hormone to analyze.\nMost hormones are small (relatively speaking) proteins.  The pure hormone specimen is usually placed into a sequential analyzer and the primary structure is determined first.  The secondary structure usually requires some sort of crystallography technique.
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Estrogens (also oestrogens) are a group of steroid compounds, named for their importance in the oestrus cycle, and functioning as the primary female sex hormone. While estrogens are present in both men and women, they are usually present at significantly higher levels in women of reproductive age. They promote the development of female secondary sex characteristics, such as breasts, and are also involved in the thickening of the endometrium and other aspects of regulating the menstrual cycle.\n\nEstrogen is produced primarily by developing follicles in the ovaries, the corpus luteum and the placenta. Follicle stimulating hormone (FSH) and luteinizing hormone (LH) stimulate the production of estrogen in the ovaries. Some estrogens are also produced in smaller amounts by other tissues such as the liver, adrenal glands and the breasts. These secondary sources of estrogen are especially important in post-menopausal women.\n\nSynthesis of estrogens starts in theca interna cells in the ovary, by the synthesis of androstenedione from cholesterol. Androstenedione is a substance of moderate androgenic activity. This compound crosses the basal membrane into the surrounding granulosa cells, where it is converted to estrone or estradiol, either immediately or through testosterone. The conversion of testosterone to estradiol, and of androstenedione to estrone, is catalyzed by the enzyme aromatase.\n\nEstradiol levels vary through the menstrual cycle, with levels highest just before ovulation.-
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http://cellbio.utmb.edu/cellbio/nucleus.htm\nhttp://www.cdli.ca/~dpower/cell/nucleus.htm\nhttp://www.cellsalive.com/cells/nucleus.htm\n\nDo some research, we're not here to complete your homework for you.
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Try these two links:\nhttp://www.scienceaid.co.uk/endocrinesystem.html\nhttp://www.scienceaid.co.uk/nervoussystem.html
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Very interesting reading:\n\n\nAnabolic-androgenic steroids are man-made substances related to male sex hormones. “Anabolic” refers to muscle-building, and “androgenic” refers to increased masculine characteristics. “Steroids” refers to the class of drugs. These drugs are available legally only by prescription, to treat conditions that occur when the body produces abnormally low amounts of testosterone, such as delayed puberty and some types of impotence. They are also prescribed to treat body wasting in patients with AIDS and other diseases that result in loss of lean muscle mass. Abuse of anabolic steroids, however, can lead to serious health problems, some irreversible.\n\nToday, athletes and others abuse anabolic steroids to enhance performance and also to improve physical appearance. Anabolic steroids are taken orally or injected, typically in cycles of weeks or months (referred to as “cycling”), rather than continuously. Cycling involves taking multiple doses of steroids over a specific period of time, stopping for a period, and starting again. In addition, users often combine several different types of steroids to maximize their effectiveness while minimizing negative effects (referred to as “stacking”).\nHealth Hazards\nThe major side effects from abusing anabolic steroids can include liver tumors and cancer, jaundice (yellowish pigmentation of skin, tissues, and body fluids), fluid retention, high blood pressure, increases in LDL (bad cholesterol), and decreases in HDL (good cholesterol). Other side effects include kidney tumors, severe acne, and trembling. In addition, there are some gender-specific side effects:\n\n    * For men — shrinking of the testicles, reduced sperm count, infertility, baldness, development of breasts, increased risk for prostate cancer.\n    * For women — growth of facial hair, male-pattern baldness, changes in or cessation of the menstrual cycle, enlargement of the clitoris, deepened voice.\n    * For adolescents — growth halted prematurely through premature skeletal maturation and accelerated puberty changes. This means that adolescents risk remaining short for the remainder of their lives if they take anabolic steroids before the typical adolescent growth spurt.\n\nIn addition, people who inject anabolic steroids run the added risk of contracting or transmitting HIV/AIDS or hepatitis, which causes serious damage to the liver.\n\nScientific research also shows that aggression and other psychiatric side effects may result from abuse of anabolic steroids. Many users report feeling good about themselves while on anabolic steroids, but researchers report that extreme mood swings also can occur, including manic-like symptoms leading to violence. Depression often is seen when the drugs are stopped and may contribute to dependence on anabolic steroids. Researchers report also that users may suffer from paranoid jealousy, extreme irritability, delusions, and impaired judgment stemming from feelings of invincibility. 1\n\nResearch also indicates that some users might turn to other drugs to alleviate some of the negative effects of anabolic steroids. For example, a study of 227 men admitted in 1999 to a private treatment center for dependence on heroin or other opioids found that 9.3 percent had abused anabolic steroids before trying any other illicit drug. Of these 9.3 percent, 86 percent first used opioids to counteract insomnia and irritability resulting from the anabolic steroids.
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It really depends on the hormone. \n\nMost protein hormones (such as insulin and HGH) are made by recombinant DNA technology. Most of the glucocorticoid (eg cortisone), mineralocorticoid (eg aldosterone) and sex hormones (eg estradiol and progesterone) are partially synthesized starting with certain readily available plant hormones. \n\nIn the past some hormones were indeed taken from animals and human cadavers, but with advances in DNA technology and improved methods of chemical synthesis, this has been almost entirely abandoned.
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"Steroid" is a general term, strictly it refers to any hormone whose molecule looks like that of cholesterol!\n\nThe most talked-about steroids are the anabolic steroids, such as testosterone.  These are what are used by athletes such as bodybuilders to achieve gains in muscle mass.  Dehydroxytestosterone is one long fancy chemical name for a popular anabolic.\n\nBut, there are also such things as "catabolic" steroids.  "Catabolic" means to break down ("anabolic" means build up, of course!).  Cortisol, a catabolic hormone made by our own bodies, is produced in response to various stressors; it tames our immune system and tries to stop it from overreacting.  In the process, it has to break down muscle tissue and become prepared to store excess energy in the form of fat.  People with excess cortisol (generally due to a tumor) generally have what is known as a Cushing's disorder, and obesity is its hallmark.\n\nCortisol and molecules like it are also given as drugs for various conditions, including multiple sclerosis, lupus, cancers, asthma, allergies, and the list goes on.  Cortisol's family is the "corticosteroids", and includes corticosterone, methylprednilosone, prednisone, and dexamethasone.  People do get put on these for various conditions, again... so if they're telling you they're taking steroids, it's probably not the kind that'll buff 'em up! ;-)
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To get the right answer you need to ask the right question. \n\nWhat you are looking for is tools and techniques for Protein Structure Modeling. \n\nJust type "Protein Structure Modeling" in Google and you should get a bazillion hits!\n\nHere are a few sites to get you going anyway: