what are the side effects of long term prescription for amoxicillen?
346962
EXECUTIVE SUMMARY\n\nSafety of Long Term Penicillin and Penicillin Derivatives\n\nThe safety of penicillin and penicillin derivatives when administered either intramuscularly, intravenously, or orally for extended periods of time (beyond the usual duration of use) can be extrapolated from multiple published studies. A review of the medical literature reveals studies in which such drugs have been used therapeutically for extended treatment durations. This includes studies of the treatment of recurrent acute otitis media, endocarditis, salmonella infections, prophylaxis of at risk populations (asplenic children, young children with sickle cell disease, patients with prior rheumatic fever), and the long term treatment of certain types of Lyme disease. Although most of these studies focus primarily on efficacy, they do routinely contain general statements indicating the safety and tolerability of the treatment under study. A few studies mentioned the presence of isolated cases of rash, gastrointestinal events, but none of the studies report the occurrence of a serious adverse event.\n\nA review of the Adverse Event Reporting System (AERS) database as performed by an Office of Post-Marketing Drug Risk Assessment (OPDRA) special programmer revealed occasional cases of adverse events associated with the administration of long term penicillin therapy, however, these adverse events were consistent with the known adverse event profile of penicillin. OPDRA concluded that "no increase in or atypical adverse drug reactions were noted in the few cases involving long-term administration of oral or intramuscular penicillin G or V (all dosage forms)." This data is generated via isolated adverse event reports submitted to the FDA, and it may be difficult to determine the overall rates of adverse events in relation to treatment duration. A similar analysis is currently being performed by OPDRA for amoxicillin and Augmentin®.\n\nThere is a higher incidence of cholestatic or mixed cholestatic-hepatocellular patterns of liver injury associated with administration of Augmentin®. This has been demonstrated by several published case reports. 8, 12, 14, 17, 20, 22, 24, 27, 28 Fatalities are very rare (on the order of one in several million) and similar hepatotoxicity is not thought to occur with amoxicillin administration. A study by Garcia-Rodriguez identified specific sub-populations who might be at increased risk for hepatotoxicity.10 These groups include older patients, and patients on long term therapy. The overall risk is still very low but was noted to be significantly higher than for the comparison group receiving amoxicillin. The information from this study was submitted in a labeling supplement and resulted in the identification of these risk groups in the label.\n\nThese antibiotics have an extensive history of use, and the lack of any serious adverse events as reported in these studies support their reputation as safe drugs. Reassurance can be derived from the fact that no increase in serious adverse events has been reported in the literature despite broad usage. Clinicians should still be aware that, although quite unlikely, when using these drugs over extended period of time, the potential exists for slight increases in the rates of specific adverse events which are infrequent enough to have escaped detection. Although there is no data to suggest such an increase (except for Augmentin® and hepatotoxicity), adverse events could include increased liver function tests, serum sickness, interstitial nephritis, effects on anti-coagulant therapy, and neutropenia. \n\nDETAILED REVIEW OF DATAc. Amoxicillin (n= 627)\n\nNine studies were identified which examined long term amoxicillin prophylaxis (4 weeks - 6 months) in children with recurrent acute otitis media. 29-37 There were 488 patients who were treated with doses ranging from 20-40 mg/kg/day of amoxicillin. In total, there were 11 adverse event reported. Four patients were report
335676
I haven't heard of any side effects. You could try Google?
1114302
all drugs and medications have side affects\nif you want to be specific you'll need to look up individual medications
343914
SHORT AND LONG TERM EFFECTS\n \n\nShort Term and Long Term Effects\n\nPhysical Symptoms:\n\nSevere weight loss - sometimes up to 50 - 100 pounds. \n\nRotting teeth - teeth may first turn gray, then black; gum disease brought on by constriction of the gums' blood vessels can cause loss of teeth. \n\nBody odor - user loses interest in personal hygiene. The chemicals used to manufacture meth are excreted through the perspiration and emit a bad smell. \n\nScars and open sores - hallucinations cause the user to scratch or gouge at imaginary "bugs." The body also releases histamines which causes itching. \n\nInability to sleep for hours or days, followed by severe agitation and a sedated crash lasting many hours or for days. \n\nPsychological/Behavioral Symptoms: \n\nDue to the drug's ability to overwhelm and over-stimulate the users' nervous system, chronic meth users may experience any or all of the following:\n\nInitial euphoria - a feeling of great happiness or well-being; bliss. \n\nDepression - feelings of sadness, dejection. \n\nDelusion - a false belief held as a result of self-deception mental disorder. \n\nPsychosis - a severe mental disorder, with or without organic damage, characterized by deterioration of normal intellectual and social functioning and by withdrawal from reality. \n\nParanoia - a chronic psychosis characterized by delusions of persecution or of grandeur. \n\nViolence - physical force exerted to violate, damage, or abuse
666580
According to my drug handbook:\n\nGI: Nausea, vomiting, anorexia, constipation, flatulence, GI irritation, diarrhea\nGU: Proteinuria, renal insufficiency, sexual dysfunction, impotence.\nINTEG: Rash, pruritus\nCNS: Vertigo, depression, stroke, insomnia, paresthesias, headache, fatigue, asthenia, dizziness\nEENT: Blurred vision, nasal congestion\nSYST: Angeioedema\nRESP: Dry cough, dyspnea\nCV: Chest pain, hypotension\nMISC: Muscle cramps\n\nKeep in mind this ia comprehensive list of all reported possible side effects/adverse reactions.
1187150
-an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; hives); \n-wheezing or shortness of breath; \n-an unusually slow or irregular heart beat; \n-swelling of the feet or lower legs; \n-leg pain or cramping; \n-sudden weight gain (more than 2 pounds in one day or 5 pounds in one week); \n-chest (heart) pain; \n-unusually cold or blue feet and hands; or \nskin rash. \n\nIf you experience any of the following less serious side effects, continue taking propranolol and talk to your doctor:\n\n-fatigue or confusion; \n-headache or dizziness; \n-weak pulse or mildly slow heart rate; \n-diarrhea, constipation, gas, nausea, or vomiting; \n-depression; \n-nightmares; or impotence (difficulty obtaining or maintaining an erection).
367392
Nothing, unless you take more than the recommended daily allowance or do it regularly. If you take painkillers regularly you'll end up with a headache when you don't take them, due to withdrawal effects.
190614
More common side effects may include: \nDizziness, light-headedness, nausea, sedation, vomiting\nLess common or rare side effects may include: \nConstipation, depressed feeling, exaggerated feeling of well-being, itchy skin, skin rash, slowed breathing (at higher doses)
112948
SIDE EFFECTS (when taken as directed):\nConstipation, dryness of the mouth, confusion, sedation, light-headedness, respiratory depression, nausea, vomiting, headache, sweating\n\nSYMPTOMS OF OVERDOSE:\nSlow breathing, seizures, dizziness, weakness, loss of consciousness, coma, confusion, cold or clammy skin, small pupils
1090588
What are the possible side effects of prednisone?\n  If you experience any of the following serious side effects, stop taking prednisone and seek emergency medical attention or contact your doctor immediately: \n\nan allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); \nincreased blood pressure (severe headache or blurred vision); or \nsudden weight gain (more than 5 pounds in a day or two). \nOther, less serious side effects may be more likely to occur. Continue to take prednisone and talk to your doctor if you experience\n\ninsomnia; \nnausea, vomiting, or stomach upset; \nfatigue or dizziness; \nmuscle weakness or joint pain; \nproblems with diabetes control; or \nincreased hunger or thirst. \nOther side effects that occur only rarely, usually with high doses of prednisone, include\n\nacne, \nincreased hair growth, \nthinning of the skin, \ncataracts, \nglaucoma, \nosteoporosis, \nroundness of the face, and \nchanges in behavior. \nSide effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
103577
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.\n\n    * Headache\n\n    * Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain\n\n    * Allergic reaction to active ingredient\n\n    * Low blood glucose level (hypoglycaemia)\n\n    * Weight gain\n\n    * Blood disorders\n\n    * Skin rashes\n\n    * Severe skin rash (erythema multiforme)\n\nThe side effects listed above may not include all of the side effects reported by the drug's manufacturer.\n\nFor more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.\n\nHow can this medicine affect other medicines?\n\nThe following drugs may enhance the effects of glibenclamide leading to low sugar levels in the blood:\nAspirin; non-steroidal anti-inflammatory drugs (NSAIDS); sulphonamide antibiotics; co-trimoxazole; ciprofloxacin; warfarin; beta blockers; ACE inhibitors; anabolic steroids; monoamine oxidase inhibitors (MAOIs); antifungals (fluconazole and miconazole); testosterone; clofibrate; phenylbutazone.\n\nThe following drugs may reduce the effect of glibenclamide and so may raise blood sugar levels:\nDiuretics (loop and thiazide diuretics); corticosteroids; combined oral contraceptives; rifampicin; chlorpromazine.\n\nGlibenclamide may alter the blood thinning effects of warfarin and other coumarins.\n\n\nHow does it work?\n\nIn patients with diabetes mellitus, there is a deficiency or absence of a hormone manufactured by the pancreas called insulin. Insulin is the main hormone responsible for the control of sugar in the blood.\n\nGlibenclamide is an antidiabetic medication which is used in those patients with maturity onset or non-insulin dependent diabetes (NIDDM). It works by lowering blood sugar levels by stimulating the production and release of insulin from the pancreas. It also promotes the movement of sugar from the blood into the cells in the body which need it.\n\nThese two mechanisms, in conjunction with a diet low in sugar and fat, allow diabetics to control their blood sugar levels more effectively.
504406
The side effects relate to the dose and type of anabolic steroid you take and how long you take them/\n\nHealth problems such as high blood pressure, liver damage, heart damage can occur if you take large doses or take steroids for long periods.   More commonly you will get pimples, headaches and when you stop taking the steroids feel depressed and lose the muscle you gained.  Yor testicles will shrink and you will have trouble with your libido and getting it up.\n\nBuild your muscle naturally through smart hard work - it will last longer, look more sexy to the ladies and you will not have any touble in the sack if you get the opportunity!\nSteroids are for lazy losers who end up being fat slobs!!!
1106632
The following side effects are associated with Tamoxifen Oral:\n\nInfrequent side effects:\nDischarge from the Vagina Less Severe \nIrregular Periods Less Severe \n"Change of Life" Signs Less Severe \nGenital Itching Less Severe \nDry Skin Less Severe \nRash Less Severe \nWeight Gain Less Severe \nHead Pain Less Severe \nFeel Like Throwing Up Less Severe \nThrowing Up Less Severe \n\n\nRare side effects:\nDisease of the Retina of the Eye Severe \nCataracts Severe \nDisease of the Cornea of the Eye Severe \nSudden Blindness and Pain Upon Moving the Eye Severe \nBlood Clot in Lung Severe \nBlood Clot Severe \nHepatitis caused by Drugs Severe \nPolyps of the Lining of the Uterus or the Endometrium Severe \nOvergrowth of the Uterine Lining Severe \nDrowsiness Severe \nFeeling Weak Severe \nCancer in the Lining of the Uterus Severe \nConfused Severe \n\n\nSide Effects \n\nTamoxifen's unwanted side effects depend on whether you have any personal history of blood clots or endometrial cancer, your susceptibility to hot flashes associated with menopause, and the ups and downs of depression. Add to these the cost of the medication, the fact that some women have real trouble sticking to the routine of taking a daily dose of pills, and many women's philosophical objection to taking any regular medication except perhaps for vitamins.\n\nAlthough most side effects are not life threatening, the lesser side effects may diminish your quality of life, sometimes to a considerable degree.\n\nBlood Clots\n\nOne potentially serious side effect of tamoxifen is blood clots, also known as thrombosis. The most common place for a clot to form is in the leg veins. These clots are dangerous because they can break loose, travel to the lung, and clog a vital blood vessel; this is called a pulmonary embolism. If you have had any history of blood clots, tamoxifen will probably not be an option for you. The possibility of pulmonary embolism is less than 1%, meaning that it's likely to affect less than one woman in a hundred taking tamoxifen. Tamoxifen can also cause inflammation of a blood vessel. Call your doctor if you notice any new swelling, redness, discomfort, or warmth in your legs.\n\nEndometrial Cancer and Other Uterine Effects\n\nAnother serious risk associated with tamoxifen treatment is cancer of the lining of the uterus (endometrial cancer) in a woman beyond menopause who still has her uterus. Regardless of tamoxifen use, women affected by breast cancer are at increased risk of developing endometrial cancer; tamoxifen, however, does make this slightly higher risk a little higher still. Here, the risk is two women in a thousand, and there are usually -- but not always -- clear early warning signs of trouble. The longer a woman takes tamoxifen, the higher her risk of developing a tamoxifen-induced endometrial cancer. (But the risk is still low, even for women taking tamoxifen for 10 years.) If an endometrial cancer is diagnosed within the first two years of taking tamoxifen, the cancer was most likely there before treatment with the drug began.\n\nEndometrial cancer -- related or unrelated to tamoxifen use -- can usually be detected in the early stages, and it is usually curable with surgery. Unexpected vaginal bleeding is usually the first sign of trouble, and should be reported to your doctor immediately. You should also have a gynecologic exam every six months. The routine Pap smear, however, is not adequate for detecting endometrial cancer, because it assesses only the health of the cervix (the mouth of the uterus). Ultrasound testing or a uterine tissue sample obtained by biopsy are the most effective ways of evaluating the endometrium, but experts claim no benefit to routine endometrial ultrasounds and biopsies unless you have symptoms. Discuss this issue with your doctor.\n\nIf you have had a hysterectomy (removal of the uterus) because of endometrial cancer, tamoxifen may be contraindicated for your treatment of breast
911364
I have been searching and all the literature and the side effects listed are all short term, there is no mention of long term effects.  I would think that the experts know very little about this as Ritalin is a relatively new drug.\nYou have been on some pretty serious drugs in a short time frame, maybe its the combination rather than just one drug which has caused your problems.\nI feel for you, its rotten on top of the problems you have already had.  I hope you find a satisfactory answer to your question...good luck x
293159
Any cordisone type medicine taken in long term therapy may cause bone degeneration.
799231
amoxicillin has a very short half-life, approx. 1 hour (if you have normal kidney function). it should be eliminated within 5-6 hours from the last dose (bad kidneys= approx. 60-70 hours).\njust to be safe, i would recommend using back up birth control for a few days after.
393125
Common Side Effects: \nCheck with your doctor if any of the following side effects continue or are bothersome:\n\nincreased appetite \nindigestion \nnervousness or restlessness \n\nLess frequent or rare: \nCheck with your doctor if any of the following side effects continue or are bothersome:\n\ndarkening or lightening of skin color \ndizziness or lightheadedness \nflushing of face or cheeks \nhiccups \nincreased joint pain (after injection into a joint) \nincreased sweating \nsensation of spinning \n\nAlways Notify Doctor: \nLess common \n\nDecreased or blurred vision \nfrequent urination \nincreased thirst