what are bisphosphonates used for?
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Bisphosphonates. Bisphosphonates slow the rate that bone is broken down in your body. This maintains bone density and reduces your risk of a broken bone.
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Two years after its approval, Amgen issued warnings that Prolia could cause serious risks like "hypocalcemia, serious infections, suppression of bone turnover, including osteonecrosis of the jaw” as well as “atypical femoral fracture” and “dermatologic adverse events." Notably, these are the same risks bisphosphonates ...
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Swallow the tablet whole. Then stay fully upright (sitting, standing, or walking) for at least 60 minutes and do not lie down until after your first food of the day. Wait at least 60 minutes after taking ibandronate before you eat or drink anything other than plain water and before taking any other medication by mouth.
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Teriparatide (brand name Forteo) and abaloparatide (brand name Tymlos) are medications used to treat osteoporosis. Forteo is a lab-made version of human parathyroid hormone (PTH) and Tymlos is a version of human parathyroid hormone-protein. These two drugs are both similar to the PTH that your body produces naturally.
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Calciferol (ergocalciferol) is vitamin D2 used to treat hypoparathyroidism (decreased functioning of the parathyroid glands), and is also used to treat rickets (softening of the bones caused by vitamin D deficiency) or low levels of phosphate in the blood (hypophosphatemia). Calciferol is available in generic form.
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Fosamax (alendronate) is a first-choice treatment for osteoporosis, but taking it can be a hassle. Prevents bone loss and lowers your risk of invasive breast cancer. Evista (raloxifene) helps to reduce bone loss and lower the risk of breast cancer in post-menopausal women, but it can cause blood clots.
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In randomized controlled trials (RCTs), alendronate, risedronate, and zoledronate have shown to reduce the risk of vertebral, nonvertebral, and hip fractures, whereas RCTs with ibandronate show antifracture efficacy at vertebral sites. Bisphosphonates are generally well tolerated and safe.
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Alendronate is also used to treat Paget's disease of bone (a condition in which the bones are soft and weak and may be deformed, painful, or easily broken). Alendronate is in a class of medications called bisphosphonates. It works by preventing bone breakdown and increasing bone density (thickness).
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Boniva (ibandronate) is a bisphosphonate drug that alters the cycle of bone formation and breakdown in the body used to treat or prevent osteoporosis in women after menopause.
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Reclast and Zometa are two different brands of zoledronic acid. Reclast is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. This medicine is for use when you have a high risk of bone fracture due to osteoporosis. Reclast is also used to treat Paget's disease of bone.
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Fosamax (alendronate sodium) and Prolia (denosumab) are used to treat and prevent osteoporosis. Fosamax is also used to treat Paget's disease. Fosamax and Prolia belong to different drug classes. Fosamax is a bisphosphonate and Prolia is a monoclonal antibody.
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Bisphosphonates include alendronate (Binosto, Fosamax), ibandronate (Boniva), risedronate (Actonel, Atelvia) and zoledronic acid (Reclast, Zometa). These are effective at lowering the risk of broken bones, which can lead to pain and disability and increase the risk of death.
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What is the role of calcium supplements when patients take bisphosphonates? They must be taken in sufficient amounts to provide foundational elements for bone growth. ... Black women are at risk of developing osteoporosis due to their lower calcium intake as a group.
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Calcium is crucial in growing new bone and maintaining bone strength. Calcium supplements are standard for treating and preventing osteoporosis -- weak and easily broken bones -- and its precursor, osteopenia. Calcium is used for many other conditions. It's an ingredient in many antacids.
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Fosamax is a prescription drug used to treat and prevent osteoporosis in adults. It was first introduced to the U.S. market in 1995 by the drug manufacturer Merck. Fosamax is specifically used to treat patients who have an increased risk of osteoporosis and a severe bone loss disease called Paget's disease of bone.
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Significantly increased weight gain of Fosamax-treated mice, particularly in the later weeks of treatment, suggest that long-term Fosamax use appears to impact metabolism, but it is unclear at this stage how these metabolic changes may lead to complications observed with long-term use of bisphosphonates.
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Uses. Vitamin D (ergocalciferol-D2, cholecalciferol-D3, alfacalcidol) is a fat-soluble vitamin that helps your body absorb calcium and phosphorus. Having the right amount of vitamin D, calcium, and phosphorus is important for building and keeping strong bones.