what are the dangers of nsaids?
482686
Except for aspirin, all over-the-counter NSAIDs now must carry a warning about the risks of heart attack and stroke along with other side effects. NSAIDs have other dangers, too. They can cause high blood pressure and kidney damage in some people. They can also cause potentially severe allergic reactions.
1232037
Conclusion. Extensive evaluation of the safety and efficacy of NSAIDs and selective COX-2 inhibitors has revealed that both drugs are equally effective and are associated with increased risk of GI, renal, and CV, adverse effects.
652701
['NSAIDs relieve fever and pain. ... ', 'When taken for a short time (no longer than 10 days), NSAIDs are safe for most people.', 'Some NSAIDs can be bought over the counter, such as aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn).', 'Other NSAIDs are prescribed by your provider.']
1446702
NSAID use might damage the lower GI tract (small bowel, colon or anus), with a rate of bleeding events that is believed to be approximately a third of that of upper GI bleeding.
175244
Taking too much ibuprofen by mouth can be dangerous. It can cause side effects such as: feeling and being sick (nausea and vomiting) stomach pain.
235521
Current evidence suggests that NSAIDs increase the risk of lower GI bleeding and perforation to a similar extent as that seen in the upper GI tract. Selective COX-2 inhibitors are as effective as traditional NSAIDs to relieve inflammation.
368800
NSAIDs possibly damage the normal large intestine, which presents as ulceration, colitis and stricture. Even though several studies found that NSAIDs can cause diverticular bleeding and perforation, flare-up of inflammatory bowel disease ,and play a role as an etiologic factor in lymphocytic colitis.
1355535
Vetprofen, like other drugs, may cause some side effects. Serious but rare side effects have been reported in dogs taking NSAIDs, including carprofen. Serious side effects can occur with or without warning and in rare situations result in death.
349117
Research has discovered that the risk of gastrointestinal (GI) side effects such as stomach ulcers and stomach bleeding increases the longer somebody takes NSAIDS. Aleve is more likely than Advil to cause GI side effects because it is longer acting.
596357
Administration of NSAIDs during the latter part of pregnancy may cause premature closure of the fetal ductus arteriosus, fetal renal impairment, inhibition of platelet aggregation, and delay labor and delivery. There are no adequate and well controlled studies of diclofenac or other NSAIDs in pregnant women.
1443549
Most NSAIDs act as nonselective inhibitors of the cyclooxygenase (COX) enzymes, inhibiting both the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) isoenzymes.
651781
15 Ibuprofen (Advil) Side Effects: Heartburn, Internal Bleeding & More.
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Gastrointestinal (GI) Problems NSAIDs can cause nausea, heartburn, vomiting, gas, belly pain, diarrhea or constipation. More serious stomach problems include ulcers and bleeding in the GI tract. Call your doctor right away if you have severe abdominal pain; a black, tarry bowel movement; or see any blood in your stool.
420033
['ibuprofen.', 'naproxen.', 'diclofenac.', 'celecoxib.', 'mefenamic acid.', 'etoricoxib.', 'indomethacin.', 'high-dose aspirin (low-dose aspirin is not normally considered to be an NSAID)']
1417400
Nonsteroidal anti-inflammatory drugs (NSAIDs) — medications commonly used to treat pain and inflammation — can increase the risk of a heart attack or stroke. It's important to take only the dose you need for as short amount of time as possible to limit the risk of heart attack or stroke.
756112
Exposure to any NSAID may cause acute kidney injury—and older age and pre-existing kidney problems are big risk factors. The risk for kidney damage is similar among all NSAIDs, so naproxen is neither better nor worse on the kidney than ibuprofen (Motrin, Advil).
1394426
An overdose of these medications may cause stomach upset, abdominal pain, and vomiting. Larger amounts of NSAIDs can injure the kidneys. Also, they may cause ulcers, bleeding, seizures, and coma.