what does oestrogen receptor positive mean?
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Describes cells that have a receptor protein that binds the hormone estrogen. Cancer cells that are estrogen receptor positive may need estrogen to grow, and may stop growing or die when treated with substances that block the binding and actions of estrogen. Also called ER positive.
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A positive result means that a person has a high amount of LH in their system. LH levels drop after ovulation, so the tests only show positive results during fertile periods.
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SERMS, such as Nolvadex (tamoxifen) and Evista (raloxifene), are synthetic hormones that bind to the estrogen receptors in a woman's breast cells in place of her own estrogen. SERMS “fake out” the estrogen receptors because, unlike natural estrogen, they do not stimulate breast cell growth.
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Also, certain health problems can cause estrogen levels to rise, including: obesity. ovarian tumors. liver disease.
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A positive test result means that you have a mutation in one of the breast cancer genes, BRCA1 or BRCA2, and therefore a much higher risk of developing breast cancer or ovarian cancer compared with someone who doesn't have the mutation. But a positive result doesn't mean you're certain to develop cancer.
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Triple-negative breast cancer is cancer that tests negative for estrogen receptors, progesterone receptors, and excess HER2 protein. These results mean the growth of the cancer is not fueled by the hormones estrogen and progesterone, or by the HER2 protein.
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They also label them as either rhesus (Rh) positive or Rh negative to denote the presence or absence of an antigen called Rh factor. For example, a person with O+ blood does not have A or B antigens on the surface of the cells but does have Rh factor. In contrast, O- blood has no A or B antigens and no Rh factor.
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The LH surge triggers ovulation, which is the start of a woman's fertile period. When an ovulation test result is positive, it means that LH levels are high, and ovulation should occur within the next 24 to 36 hours.
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Breast cancer subtypes and inherited mutations 60% to 80% of the breast cancers in women with a BRCA1 mutation are triple negative, as discussed above, 70% to 80% of the breast cancers in women with a BRCA2 mutation are estrogen receptor-positive, progesterone receptor-positive, and HER2-negative.
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In Wikidata. Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body. They act by blocking the estrogen receptor (ER) and/or inhibiting or suppressing estrogen production.
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Estrogen receptor downregulators, called ERDs for short, block the effects of estrogen in breast tissue. ERDs work in a similar way to SERMs, such as tamoxifen. ERDs sit in the estrogen receptors in breast cells. If an ERD is in the estrogen receptor, there is no room for estrogen and it can't attach to the cell.
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Hormone receptor-negative (or hormone-negative) breast cancers have neither estrogen nor progesterone receptors. Treatment with hormone therapy drugs is not helpful for these cancers. These cancers tend to grow faster than hormone receptor-positive cancers.
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EstroG-100® is a patented drug-free ingredient formulation clinically proven to alleviate menopause-related symptoms without side effects or unwanted changes to body weight. Health Canada NPN 80026169. RESEARCH. BACKED. Three human clinical trials and five toxicity studies substantiate EstroG-100®'s efficacy and safety ...
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As the strongest of the three estrogens, oestradiol (E2) -also known as estradiol- is an important player in the female reproductive system. Understanding this hormone will help women take better control of their reproductive health. Oestradiol is one of three estrogen hormones naturally produced in the body.
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Sometimes, elevated follicle-stimulating hormone (FSH) levels are measured to confirm menopause. When a woman's FSH blood level is consistently elevated to 30 mIU/mL or higher, and she has not had a menstrual period for a year, it is generally accepted that she has reached menopause.
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Testosterone and Oestrogen are sex hormones that are typically considered male or female. They are, however, present in both men and women.
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Estrogen is a female hormone made mainly in the ovaries. It's important for sexual development and other body functions. From your first monthly period until menopause, estrogen stimulates normal breast cells. A higher lifetime exposure to estrogen may increase breast cancer risk.