what would cause high creatinine levels in urine?
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['Chronic kidney disease. Share on Pinterest Intense exercise can result in increased creatinine levels. ... ', 'Kidney obstruction. ... ', 'Dehydration. ... ', 'Increased consumption of protein. ... ', 'Intense exercise. ... ', 'Certain medications.']
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Conditions that damage your kidneys can also make you have too much protein in your urine. The two most common are diabetes and high blood pressure. Other serious conditions that can cause proteinuria include: Immune disorders such as lupus.
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Creatinine is usually measured less often and only in the morning. So peaks of elevated creatinine may occur frequently in clinical studies but were not detected because of the transient nature of these events.
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Creatinine clearance ( CrCl ) is an estimate of Glomerular Filtration Rate ( GFR ); however, CrCl is slightly higher than true GFR because creatinine is secreted by the proximal tubule (in addition to being filtered by the glomerulus).
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Causes. Most of the time, a high uric acid level occurs when your kidneys don't eliminate uric acid efficiently. Things that may cause this slow-down in the removal of uric acid include rich foods, being overweight, having diabetes, taking certain diuretics (sometimes called water pills) and drinking too much alcohol.
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Generally, a high blood urea nitrogen level means your kidneys aren't working well. But elevated blood urea nitrogen can also be due to: Urinary tract obstruction. Congestive heart failure or recent heart attack.
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Creatinine is removed from the blood chiefly by the kidneys, primarily by glomerular filtration, but also by proximal tubular secretion. Little or no tubular reabsorption of creatinine occurs. If the filtration in the kidney is deficient, blood creatinine concentrations rise.
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A high uric acid level is known as hyperuricemia. This can lead to a disease called gout that causes painful joints that accumulate urate crystals. It can also make your blood and urine too acidic.
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Certain medications can affect the level of protein in your urine, so your doctor may ask you to stop taking a medication or to change your dose before the test. Medications that affect protein levels in the urine include: antibiotics, such as aminoglycosides, cephalosporins, and penicillins.
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What are considered high creatinine levels? A person with only one kidney may have a normal level of about 1.8 or 1.9. Creatinine levels that reach 2.0 or more in babies and 5.0 or more in adults may indicate severe kidney impairment.
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A creatinine blood test doesn't require much preparation. Fasting isn't necessary. You can and should eat and drink the same as you do normally to get an accurate result. However, it's important to tell your doctor about any prescription or over-the-counter (OTC) medications you're currently taking.
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['A bacterial urinary tract infection. This is the most common cause of a high white blood cell count in urine.', 'Inflammation of the urinary tract or kidneys.']
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High values for both BUN and creatinine indicate that the kidneys are not working well and may be in failure. In this situation a protein:creatinine ratio greater than 0.4 in a cat and 0.5 in a dog indicates there is significant protein loss through the kidneys, and a diagnosis of primary renal disease can be made.
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['Kidney injury, damage or failure.', 'Acute Interstitial Nephritis (AIN)', 'Bone fracture of the hip, wrist or spine.', 'Vitamin B-12 deficiency.', 'Clostridium difficile-associated diarrhea (caused by intestinal infection)', 'Lupus Erythematosus.', 'Low magnesium levels.']
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['A viral infection.', 'Inflammation of the kidney or bladder.', 'A blood disorder.', 'Bladder or kidney cancer.']
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Renal function, assessed by serum creatinine, creatinine clearance and urinary protein measurements were improved over the short term duration of this study. There was a significant decline in serum creatinine with 30 and 45 g, and a concomitant increase in creatinine clearance with increasing flaxseed dose.
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Urinary tract changes The increased blood volume and cardiac output during pregnancy cause a 50-60% increase in renal blood flow and glomerular filtration rate (GFR). This causes an increased excretion and reduced blood levels of urea, creatinine, urate and bicarbonate.