why is pfk the first committed step?
475841
The first committed step is actually phosphofructokinase because then you are committed to proceeding all the way to pyruvate, i.e. to completing glycolysis. ... The high affinity makes it possible to initiate glycolysis even when glucose is low. These hexokinases are allosterically inhibited by their own product, G-6P.
36289
Four molecules of ATP per glucose are actually produced, however, two are consumed as part of the preparatory phase. The initial phosphorylation of glucose is required to increase the reactivity (decrease its stability) in order for the molecule to be cleaved into two pyruvate molecules by the enzyme aldolase.
1058309
first step - the first of a series of actions. opening move, initiative, opening. commencement, start, beginning - the act of starting something; "he was responsible for the beginning of negotiations"
192397
[intrinsic column flags] - PK: primary key (column is part of a pk) - NN: not null (column is nullable) - UQ: unique (column is part of a unique key) - AI: auto increment (the column is auto incremented when rows are inserted)
912589
When the Cpk is greater than or equal to one, the process is considered capable of producing a product within specification limits. ... It will equal zero when the actual process average matches or falls outside one of the specification limits. The Cpk index can never be greater than the Cp, only equal to it.
1183542
KP and ⃗ PK are not the same rays because they each have a different endpoint and are going in different directions.
753990
When the muscle starts to contract and needs energy, creatine phosphate transfers its phosphate back to ADP to form ATP and creatine. This reaction is catalyzed by the enzyme creatine kinase and occurs very quickly; thus, creatine phosphate-derived ATP powers the first few seconds of muscle contraction.
509082
The basic idea behind PKCE is proof of possession. The client app should give proof to the authorization server that the authz code belongs to the client app in order for the authorization server to issue an access token for the client app. ... Both the code verifier and the code challenge is created by the client app.
535799
['Stage 1. Hexokinase breaks a phosphate off of an ATP, this ATP becomes ADP. ... ', 'Stage 2. phosphoglucoisomerase isomerizes the Glucose-6-phosphate to turn it into Fructose-6-phosphate.', 'Stage 3. Phosphofructokinase breaks a phosphate off of another ATP. ... ', 'Stage 4. ... ', 'Stage 5. ... ', 'Stage 6. ... ', 'Stage 7. ... ', 'Stage 8.']
79481
Substrate level phosphorylation is when ADP is converted to ATP by the direct transfer of a phosphate group. The phosphate group is donated or transfered from a phosphorylated intermediate. This is in contrast to oxidative phosphorylation, where a chemiosmotic gradient is used to power the phosphorylation process.
333375
A penalty kick (commonly known as a penalty or a PK) is a method of restarting play in association football, in which a player is allowed to take a single shot on the goal while it is defended only by the opposing team's goalkeeper.
7035
Pyruvate kinase. Pyruvate kinase is the enzyme involved in the last step of glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to adenosine diphosphate (ADP), yielding one molecule of pyruvate and one molecule of ATP.
1115580
PKF: This stands for pre-key stage, foundations for the expected standard. This means that your child is working at a level that is significantly lower than the expected.
920677
Glycolysis can be divided into two phases: energy consuming (also called chemical priming) and energy yielding. The first phase is the energy-consuming phase, so it requires two ATP molecules to start the reaction for each molecule of glucose.
219465
Heel-first walking is more efficient than toe-first at transferring stored energy into motion, so our muscles don't have to do as much work. With each step, some energy of motion is lost when your feet hit the ground.
1416255
The Patricia Kane protocol (PK protocol) is an experimental treatment for neurological disease involving intravenous infusion of phospholipids and methylation factors, along with dietary changes and supplements.
498277
The gist of the matter is that once you push data on a connection you have to wait for the receiver to get all of it before it gets to the new data. This is where the URG flag kicks in. When you send urgent data, your TCP creates a special segment in which it sets the URG flag and also the urgent pointer field.