what is selective reabsorption in the kidney?
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Selective reabsorption is the process whereby certain molecules (e.g. ions, glucose and amino acids), after being filtered out of the capillaries along with nitrogenous waste products (i.e. urea) and water in the glomerulus, are reabsorbed from the filtrate as they pass through the nephron.
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Where does the bulk of reabsorption occur in the nephron? Further bulk reabsorption of sodium occurs in the loop of Henle. Regulated reabsorption, in which hormones control the rate of transport of sodium and water depending on systemic conditions, takes place in the distal tubule and collecting duct.
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The majority of water reabsorption that occurs in the nephron is facilitated by the AQPs. Most of the fluid that is filtered at the glomerulus is then reabsorbed in the proximal tubule and the descending limb of the loop of Henle.
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Most people know that a major function of the kidneys is to remove waste products and excess fluid from the body. These waste products and excess fluid are removed through the urine.
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The kidneys can adjust the concentration of the urine to reflect the body's water needs, conserving water if the body is dehydrated or making urine more dilute to expel excess water when necessary. ADH is a hormone that helps the body to retain water by increasing water reabsorption by the kidneys.
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Potassium ion, sodium chloride, calcium ion, amino acids, glucose, bicarbonate ion and water are reabsorbed back into the blood stream. Any filtered amino acids and glucose are also reabsorbed back into the blood stream. Hydrogen ions, uric acid and drugs are secreted from the blood into the proximal convoluted tubule.
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Creatinine clearance ( CrCl ) is an estimate of Glomerular Filtration Rate ( GFR ); however, CrCl is slightly higher than true GFR because creatinine is secreted by the proximal tubule (in addition to being filtered by the glomerulus). The additional proximal tubule secretion falsely elevates the CrCl estimate of GFR .
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Once the filtrate passes through the thick ascending limb of Henle, it enters the distal convoluted tubule, which is a duct of the renal tubule located in the kidney's cortex that reabsorbs calcium, sodium, and chloride and regulates the pH of urine by secreting protons and absorbing bicarbonate.
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Reabsorption and Secretion About two-thirds of the filtered salts and water and all of the filtered organic solutes (mainly glucose and amino acids) are reabsorbed from the filtrate by the blood in the peritubular capillaries. Reabsorption occurs mainly in the proximal convoluted tubule and the loop of Henle.
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In chronic kidney disease, renal adaptive mechanisms allow the kidneys to maintain potassium homeostasis until the glomerular filtration rate (GFR) decreases to less than 15-20 mL/min.
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GFR is measured as the clearance of exogenous filtration markers that are eliminated exclusively by glomerular filtration, including inulin, iohexol, iothalamate, technetium 99m diethylenetriamine pentaacetic acid (99mTc-DTPA) and chromium 51-ethylenediamine tetraacetic acid (51Cr-EDTA).
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Filtration. Filtration takes place in the glomerulus , which is the vascular beginning of the nephron . Approximately one-fourth of the blood flow from cardiac output circulates through the kidney, the greatest rate of blood flow for any organ .
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Most people know that a major function of the kidneys is to remove waste products and excess fluid from the body. These waste products and excess fluid are removed through the urine. The production of urine involves highly complex steps of excretion and re-absorption.
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Each nephron begins with a filtration component that filters the blood entering the kidney. ... The major functions of these lining cells are the reabsorption of water and small molecules from the filtrate into the blood, and the secretion of wastes from the blood into the urine.
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The primary function of nephron is removing all waste products including the solid wastes, and other excess water from the blood, converting blood into the urine, reabsorption, secretion, and excretion of numerous substances.
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Selective reabsorption occurs because during ultrafiltration, important components of the blood are filtered out and they need to be reabsorbed into the body. ... This occurs by them diffusing from the filtrate into the cells lining the proximal convoluted tubule.
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The blood is filtered at a high pressure and the kidney selectively reabsorbs any useful materials such as glucose, salt ions and water. After it has been purified, the blood returns to the circulatory system through the renal vein . The waste is urine.