what is the difference between drug selectivity and specificity?
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Efficacy (also referred to as intrinsic activity) of a drug is the ability of the drug to elicit a response when it binds to the receptor. ... Selectivity refers to a drug's ability to preferentially produce a particular effect and is related to the structural specificity of drug binding to receptors.
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As nouns the difference between specific and particular is that specific is a distinguishing attribute or quality while particular is a small individual part of something larger; a detail, a point.
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The only difference is that, enrichment media is in liquid state, i.e. in a nutrient broth. And selective media is a semi solid. ... This is more lab stuff than clinical medicine but enrichment just encourages growth with nutrients while selective also has something to inhibit other pathogens.
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['Adsorption - the property of how well a substance in the mixture sticks to the chromatographic column. The higher the adsorption the slower the substance will move along the column.', 'Solubility - the property of how well a substance in the mixture dissolves into the solvent.']
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Enzyme specificity Each different type of enzyme will usually catalyse one biological reaction. Enzymes are specific because different enzymes have different shaped active sites. The shape of an enzyme's active site is complementary to the shape of its specific substrate or substrates. This means they can fit together.
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The difference between the two markets is that a shipment of drugs can be sold only once before it is consumed, but a human being's body can be sold and resold for years at a time.
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Specific activity. This parameter is obtained by dividing total activity by total protein. Yield. ... This parameter is a measure of the increase in purity and is obtained by dividing the specific activity, calculated after each purification step, by the specific activity of the initial extract.
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OTC drugs are monitored by the FDA, but it is not as strict as the process prescription drugs must go through. Manufacturers are required to make drugs only based on a specific formula with regards to the strength of the drug and they must have FDA approved labeling and FDA specific dosage to be on the market.
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Research for a new drug begins in the laboratory. Drugs undergo laboratory and animal testing to answer basic questions about safety. Drugs are tested on people to make sure they are safe and effective.
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API – Active Pharmaceutical Ingredient – is the basic drug itself with the desired medicinal (pharmaceutical) properties. Also referred to as Bulk Drugs. Intermediates – Most chemical reactions are stepwise, that is they take more than one elementary step to complete.
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These proteins are characterized by being open to both the intracellular and extracellular space at the same time. By contrast, carrier proteins are only open to the inside or outside of a cell at any given time. Channels or pores are typically designed so that only one specific substance can pass through.
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['Discovery.', 'Product Characterization.', 'Formulation, Delivery, Packaging Development.', 'Pharmacokinetics And Drug Disposition.', 'Preclinical Toxicology Testing And IND Application.', 'Bioanalytical Testing.', 'Clinical Trials.']
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What is the difference between a generic, formulary and specialty drug? A generic drug is identically equivalent to the brand name drug in form, safety, strength, quality and intended use. ... A formulary drug is a drug that is listed on a preferred drug list from your insurance carrier.
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In medical diagnosis, test sensitivity is the ability of a test to correctly identify those with the disease (true positive rate), whereas test specificity is the ability of the test to correctly identify those without the disease (true negative rate).
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When used as nouns, general means a general fact or proposition, whereas specific means a distinguishing attribute or quality. When used as adjectives, general means including or involving every part or member of a given or implied entity, whole etc, whereas specific means explicit or definite.
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Enzymes are specific because different enzymes have different shaped active sites. The shape of an enzyme's active site is complementary to the shape of its specific substrate or substrates. This means they can fit together.
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The difference between the diagnostic chemicals and the pharmaceutical and the biochemical reaction is that diagnostic chemicals are essentially neutral in terms of their intended effect however their actual affect is often either neutral or negative.