why hrt causes breast cancer?
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Why does HRT increase breast cancer risk? HRT helps relieve menopausal symptoms by increasing oestrogen levels. It's not fully understood why HRT increases the risk of breast cancer, but research indicates that the higher levels of oestrogen help some breast cancers to grow.
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['Breast cancer.', 'Breast cysts.', 'Cell secretions or debris.', 'Ductal carcinoma in situ (DCIS)', 'Fibroadenoma.', 'Mammary duct ectasia.', 'Previous injury or surgery to the breast (fat necrosis)', 'Previous radiation therapy for cancer.']
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['Being overweight. Excess body fat is one of the main causes of estrogen dominance. ... ', 'Stress. Chronic stress is one of the main reasons women become estrogen dominant. ... ', 'Environment.']
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Among women age 65 and older, those who took estrogen alone or estrogen plus progestin had an increased risk of developing dementia (7, 8). Stroke, blood clots, and heart attack. Women who took either combined hormone therapy or estrogen alone had an increased risk of stroke, blood clots, and heart attack (1, 2).
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This includes hot flashes, night sweats, sleep problems, vaginal dryness, mood swings, anxiety, decreased sexual desire, fatigue, and headaches. Doctors may also recommend HRT to decrease the risk of osteoporosis.
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Stopping HRT may affect your bone health. The estrogen in HRT helps protect your bones by preventing bone loss, which can lead to osteoporosis. Once you stop taking estrogen, you may develop brittle bones.
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HRT Use Raises Risk of Stomach Trouble. MONDAY, Sept. 8, 2008 (HealthDay News) -- Women who take hormones to relieve symptoms of menopause have a higher risk of developing symptoms of gastroesophageal reflux disease (GERD).
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Estrogen is one of the hormones your body uses to produce sperm. High estrogen levels can slow down sperm production and make it harder to create healthy sperm. Gynecomastia. Increased estrogen can cause more breast tissue to develop than normal.
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The study, of 54,000 women who used hormone replacement therapy (HRT), found that those who used estrogen patches were one-third less likely to develop blood clots in the legs or lungs. That was in comparison to women who used estrogen-only pills.
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The risk for breast cancer increases with age; most breast cancers are diagnosed after age 50. Genetic mutations. Inherited changes (mutations) to certain genes, such as BRCA1 and BRCA2. Women who have inherited these genetic changes are at higher risk of breast and ovarian cancer.
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Naturally occurring estrogen and progesterone stimulate the development and growth of some cancers (e.g., cancers that express receptors for these hormones, such as breast cancer). Because birth control pills contain synthetic versions of these female hormones, they could potentially also increase cancer risk.
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It found more than 1 year's use of HRT increased the risk of breast cancer, with the risk increasing the longer HRT was used. Women appear to remain at increased risk more than 10 years after they'd stopped taking HRT. The risk was greater with combined oestrogen and progestogen HRT than oestrogen-only HRT.
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Aromatase inhibitors tend to cause fewer serious side effects than tamoxifen, such as blood clots, stroke, and endometrial cancer. But aromatase inhibitors can cause more heart problems, more bone loss (osteoporosis), and more broken bones than tamoxifen, at least for the first few years of treatment.
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['Changes in the balance of female hormones in the body. ... ', 'More years of menstruation. ... ', 'Never having been pregnant. ... ', 'Older age. ... ', 'Obesity. ... ', 'Hormone therapy for breast cancer. ... ', 'An inherited colon cancer syndrome.']
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The estrogen in HRT helps protect your bones by preventing bone loss, which can lead to osteoporosis. Once you stop taking estrogen, you may develop brittle bones. However, lifestyle, dietary and nonhormonal medications can be very effective in preventing bone loss and osteoporosis.
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It is hypothesized that the longer a woman is exposed to estrogen, the higher her risk of ovarian cancer. Since high levels of estrogen are present only during the childbearing years, the longer the woman menstruates, the higher her risk.
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The combined pill contains oestrogen and, as it is known oestrogen can stimulate breast cancer cells to grow, the potential for extra oestrogen to increase the risk of breast cancer has been recognised for some time. However, any increase in risk needs to be seen in context.