what is type 1 diabetes ncbi?
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Type 1 diabetes (T1D) is a chronic disease caused by immune-mediated destruction of insulin producing beta cells in the pancreas[1]. The destruction of beta cells results in insulin insufficiency, and patients develop life-threatening hyperglycemia that clinically manifests with weight loss, polyuria, and polydipsia.
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The main risk factors for type 1 diabetes include: Family history: Having a parent or sibling with type 1 diabetes increases the risk of a person having the same type. If both parents have type 1 diabetes, the risk is even higher. Age: Type 1 diabetes usually develops in younger adults and children.
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Benefits. Type 1 diabetes was included in the Equality Act in 2010. This means that Type 1 diabetes is described as a disability. Although a lot of people with Type 1 wouldn't consider themselves disabled, it does mean that you're protected from discrimination at work or school because of your diabetes.
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If you have either Type 1 or Type 2 diabetes, it means you have too much glucose (a type of sugar) in your blood. This is the same for both types. But the difference between them is how this happens. If you have Type 1 diabetes, it means you have an autoimmune condition.
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Overview. Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, is a chronic condition in which the pancreas produces little or no insulin. Insulin is a hormone needed to allow sugar (glucose) to enter cells to produce energy.
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What causes type 1 diabetes? Type 1 diabetes occurs when your immune system, the body's system for fighting infection, attacks and destroys the insulin-producing beta cells of the pancreas. Scientists think type 1 diabetes is caused by genes and environmental factors, such as viruses, that might trigger the disease.
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Type 1 diabetes is a disorder in which the pancreas fails to produce enough insulin. This can be detected from an early age. It is characterised by uncontrolled high blood glucose levels and it can be controlled by injecting insulin.
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The exact cause of type 1 diabetes is unknown. But in most people with type 1 diabetes, the body's immune system — which normally fights harmful bacteria and viruses — mistakenly destroys insulin-producing (islet) cells in the pancreas. Genetics and environmental factors appear to play a role in this process.
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Types of Diabetes Type 1 diabetes is an autoimmune disease with a fairly sudden onset. While it is most often known for being diagnosed in young children and teens (often known as juvenile diabetes), it's actually almost as common for people in their 20's & 30's (and beyond) to be diagnosed.
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What Is Type 2 Diabetes? The two types of diabetes are type 1 and type 2. Both make blood sugar levels higher than normal but they do so in different ways. Type 1 diabetes happens when the immune system attacks and destroys the cells of the pancreas that produce insulin.
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In short, however, the answer is “no.” Type 1 and type 2 diabetes, two of the most common forms of diabetes, are actually two very different conditions. Type 1 diabetes is an autoimmune disease, which means that the body attacks the cells in the pancreas that make insulin.
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A series of studies have reported a constant global rise in the incidence of type 1 diabetes. Epidemiological and immunological studies have demonstrated that environmental factors may influence the pathogenesis, leading to a cell-mediated pancreatic β-cell destruction associated with humoral immunity.
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The exact cause of type 1 diabetes is unknown. Usually, the body's own immune system — which normally fights harmful bacteria and viruses — mistakenly destroys the insulin-producing (islet, or islets of Langerhans) cells in the pancreas. Other possible causes include: Genetics.
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In type 1 diabetes the immune system erroneously attacks the beta cells that produce insulin in your pancreas. It causes permanent damage, leaving your pancreas unable to produce insulin. Exactly what triggers the immune system to do that isn't clear.
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Type 1 diabetes (T1D) is an autoimmune disease that occurs when a person's pancreas stops producing insulin, the hormone that controls blood-sugar levels. T1D develops when the insulin-producing pancreatic beta cells are mistakenly destroyed by the body's immune system.
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Type 1 diabetes is an auto-immune disease that results in the destruction of β-cells in the pancreas1. With the destruction of β-cells, the body cannot produce enough insulin to maintain energy homeostasis. Onset of type 1 diabetes typically occurs in children and young adults1.
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About type 1 diabetes. Type 1 diabetes causes the level of glucose (sugar) in your blood to become too high. It happens when your body can't produce enough of a hormone called insulin, which controls blood glucose. You need daily injections of insulin to keep your blood glucose levels under control.