how are the concentrations of ldl and hdl associated with the risk for heart disease and disorders?
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High levels of LDL cholesterol lead to atherosclerosis increasing the risk of heart attack and ischemic stroke. HDL cholesterol reduces the risk of cardiovascular disease as it carries cholesterol away from the blood stream.
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High-Density Lipoproteins (HDL) In a healthy individual, it is composed of approximately 33% protein, 29% phospholipid, and 8% triacylglycerol. The role of HDL is to collect fat molecules such as phospholipids, cholesterol, and triglycerides in the cells of the body and transport it to the liver to be broken down.
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An excess amount of blood lipids can cause fat deposits in your artery walls, increasing your risk for heart disease.
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High cholesterol is associated with an elevated risk of cardiovascular disease. That can include coronary heart disease, stroke, and peripheral vascular disease. High cholesterol has also been linked to diabetes and high blood pressure.
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Although the risks are rare, very low levels of LDL cholesterol may be associated with an increased risk of: Cancer. Hemorrhagic stroke. Depression.
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Your body needs cholesterol to build healthy cells, but high levels of cholesterol can increase your risk of heart disease. With high cholesterol, you can develop fatty deposits in your blood vessels. Eventually, these deposits grow, making it difficult for enough blood to flow through your arteries.
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Therefore, if you have a high HDL and your LDL is also high, then you have not necessarily cancelled out your risk of heart disease just because your HDL is high. So we focus on driving the LDL as low as we need to, depending on your risk.
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Atherosclerosis is a multifactorial disease. The impact of traditional risk factors such as age, sex, elevated blood pressure, smoking, high levels of LDL cholesterol, and low levels of HDL cholesterol on CHD risk has long been demonstrated beyond any doubt.
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This type of fat comes mainly from animal sources of food, such as red meat, poultry and full-fat dairy products. Saturated fats raise high-density lipoprotein (HDL or "good") cholesterol and low-density lipoprotein (LDL or "bad") cholesterol levels, which may increase your risk of cardiovascular disease. Trans fat.
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LDL (low-density lipoprotein), sometimes called “bad” cholesterol, makes up most of your body's cholesterol. High levels of LDL cholesterol raise your risk for heart disease and stroke.
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High-density lipoprotein (HDL) cholesterol is known as the "good" cholesterol because it helps remove other forms of cholesterol from your bloodstream. Higher levels of HDL cholesterol are associated with a lower risk of heart disease.
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HDL helps rid your body of excess cholesterol so it's less likely to end up in your arteries. LDL is called “bad cholesterol” because it takes cholesterol to your arteries, where it may collect in artery walls.
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The lipids need to be attached to the proteins so they can move through the blood. HDL and LDL have different purposes: HDL stands for high-density lipoproteins. It is sometimes called the "good" cholesterol because it carries cholesterol from other parts of your body back to your liver.
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An excess of LDL can result in plaque buildup on arterial walls which can ultimately result in atheroscerlosis. That is the hardening of the arteries and can lead to heart diseases like a heart attack or stroke. Unlike LDL, higher HDL levels can actually lower the risk of heart disease.
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Lower levels put you at a higher risk of heart disease. A review of several studies on zinc and cholesterol levels suggests that supplementing with more than 50 mg of zinc per day may lower your “good” HDL levels and not have any effect on your “bad” LDL cholesterol ( 11 , 12 , 13 ).
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Dangers of Low HDL From the standpoint of heart health, the total cholesterol level can never be too low. A problem, however, arises when the HDL drops below 40 mg/dL. Quite simply, the less HDL there is in your blood, the less LDL you can clear from the body.
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A high blood cholesterol level increases your risk of coronary artery disease. Lower cholesterol is usually better, but in rare cases having a very low level of low-density lipoprotein (LDL, or "bad") cholesterol or a very low total cholesterol level has been associated with some health problems.