are enhancers cis or trans acting?
155753
Enhancers are cis-acting sequences that can greatly increase transcription rates from promoters on the same DNA molecule; thus, they act to activate, or positively regulate, transcription. ... Different DNA sequences serve as target-recognition sites for specific trans-acting regulatory proteins.
174566
Cis–trans isomerism, also known as geometric isomerism or configurational isomerism, is a term used in organic chemistry. ... In the context of chemistry, cis indicates that the functional groups are on the same side of the carbon chain while trans conveys that functional groups are on opposing sides of the carbon chain.
876132
transcription factors regulate basal genes while regulatory transcription factors control all of the other genes. General transcription factors are essential for any transcription for all genes while regulatory transcription factors regulate transcription of specific genes.
169466
Key points: Transcription factors are proteins that help turn specific genes "on" or "off" by binding to nearby DNA. Transcription factors that are activators boost a gene's transcription. ... Groups of transcription factor binding sites called enhancers and silencers can turn a gene on/off in specific parts of the body.
203044
Update: This word was added in April 2017. Cisgender (also styled as cisgendered and often shortened to cis) describes someone whose internal sense of gender corresponds with the sex the person had or was identified as having at birth. Most people can be described as cisgender.
190216
The trans-acting elements are transcription factors or other DNA-binding proteins which recognise and bind to specific sequences in the cis-acting elements to initiate, enhance or suppress transcription.
1233211
First, let's clear up one misleading statement: ZMA is not a testosterone booster. Any pro-hormone statements about ZMA are unfounded and under-researched.
830792
Cis is the high energy configuration of the double bond; a cis bond forms with the two largest substituents on the same side of the double bond. Trans bonds are low energy configurations where the two largest substituents are on opposite sides of the double bond.
1347557
cis/trans nomenclature is effective only when the alkene has two different groups on each carbon atom of the double bond and each carbon has one of the same group. The structure with the pink groups on opposite sides is trans. ... To remove the ambiguity, we use the E/Z system. You can always use the E/Z system.
455242
Promoter-proximal elements, which are relatively short (≈15–30 base pairs), are located within the first ≈200 base pairs upstream of the cap site. Enhancers, in contrast, usually are 100 – 200 base pairs long and may be located up to 50 kilobases upstream or downstream from the cap site or within an intron.
629768
Cis–trans isomerism, also known as geometric isomerism or configurational isomerism, is a term used in organic chemistry. ... Cis-trans isomers are stereoisomers, that is, pairs of molecules which have the same formula but whose functional groups are rotated into a different orientation in three-dimensional space.
1210662
Cisgender. Cisgender (sometimes cissexual, often abbreviated to simply cis) is a term for people whose gender identity matches their sex assigned at birth. For example, someone who identifies as a woman and was assigned female at birth is a cisgender woman.
959698
YY1 is a structural regulator of enhancer- promoter interactions and facilitates gene expression.
539248
Cis- and trans-platin (see Figure 37) are examples of geometric isomers based on the different arrangement of groups at a single atom. Cis- and trans-2-butene differ in the arrangement of the methyl groups about the double bonds. ... Optical isomers are mirror images that are not superimposable.
595502
Cisgender. Cisgender (sometimes cissexual, often abbreviated to simply cis) is a term for people whose gender identity matches their sex assigned at birth.
975605
Cisgender is a word used to describe gender identity. Straight, on the other hand, is used to describe sexual orientation. Being cisgender isn't the same thing as being straight, but they can overlap: People can be both cisgender and straight.
1065781
While it remains to be investigated if CDK4/6i may regulate MYC in a tissue-specific manner, we provide evidence that Palbociclib induces downregulation of MYC and its target genes involved in HR repair, causing synthetic lethality with PARP inhibition in ovarian cancer cells.