what is the difference between amlodipine and nifedipine?
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Nifedipine is an effective compound for the treatment of hypertension. However, even as a tablet formulation it is relatively short acting requiring two or three times daily administration. Amlodipine is a long-acting calcium antagonist and effectively lowers BP in patients with essential hypertension.
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Calcium channel blockers are prescription medications that relax blood vessels and increase the supply of blood and oxygen to the heart while also reducing the heart's workload. Examples of calcium channel blockers include: Amlodipine (Norvasc)
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Nifedipine lowers your blood pressure and makes it easier for your heart to pump blood around your body. The most common side effects include headache, flushing, constipation, feeling tired and swollen ankles. These usually improve after a few days of treatment.
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Amlodipine is a calcium channel blocker. Amlodipine relaxes (widens) blood vessels and improves blood flow. Benazepril is an ACE inhibitor.
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Both amlodipine and cilnidipine have shown equal efficacy in reducing blood pressure in hypertensive individuals. But cilnidipine being N-type and L-type calcium channel blocker, associated with lower incidence of pedal edema compared to only L-type channel blocked by amlodipine.
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L 29 (Amlodipine Besylate 5 mg) It is supplied by Lupin Pharmaceuticals, Inc.. Amlodipine is used in the treatment of high blood pressure; raynaud's syndrome; angina; heart failure; coronary artery disease and belongs to the drug class calcium channel blocking agents.
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This product is a combination of two drugs: a calcium channel blocker (amlodipine) and an ACE inhibitor (benazepril). It is used to treat high blood pressure.
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Calcium channel blockers are available in short-acting and long-acting forms. Short-acting medications work quickly, but their effects last only a few hours. Long-acting medications are slowly released to provide a longer lasting effect.
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Verapamil is more effective in reducing blood pressure and rate-pressure product responses to stress compared with amlodipine. Although plasma noradrenaline is lower with verapamil at rest and after stress, the increase during stress is not different.
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Highlights for nifedipine Nifedipine oral tablet is available as both a generic drug and brand-name ride. Brand names: Adalat CC, Afeditab CR, and Procardia XL. Nifedipine tablets are an extended-release form of the drug. Nifedipine is also available in immediate-release oral capsules.
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A fixed combination of ramipril with amlodipine is an effective antihypertensive drug with a good tolerability profile. It effectively provides both blood pressure control and positive cardioprotective and nephroprotective effect.
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Abstract. Amlodipine, marketed primarily as a besylate salt, is a calcium channel blocker used for treating essential hypertension. Amlodipine maleate is another salt that is considered, in terms of pharmacokinetics and pharmacodynamics, similar to amlodipine besylate.
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Nifedipine produces vasodilation by blocking calcium channels in arterial VSM, thereby activating baroreceptor reflex. The direct net effect of which is decreased blood pressure.
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Amlodipine seems to be more effective than felodipine when the drugs are compared in the same dose, with regard to the effect on clinic BP 24 h after dosing and to ambulatory BP during the night. The longer elimination half-life of amlodipine as compared to felodipine is the probable reason for this finding.
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Nifedipine is a medicine used to treat high blood pressure. If you have high blood pressure, taking nifedipine helps to prevent future heart disease, heart attacks and strokes. Nifedipine is also used to prevent chest pain caused by angina. Occasionally, it's used to treat Raynaud's phenomenon and chilblains.
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Amlodipine (Norvasc) is a great drug — but it takes 8 hours for the drug to reach its peak drug concentration, and about a week to reach steady-state full antihypertensive effect.
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Are Norvasc and Prinivil the Same Thing? Norvasc (amlodipine) and Prinivil (lisinopril) are both used to treat high blood pressure (hypertension).