where are mhc molecules located?
150944
The MHC molecules are glycoproteins encoded in a large cluster of genes located on chromosome 6. They were first identified by their potent effect on the immune response to transplanted tissue (see later). For that reason, the gene complex was termed the ''major histocompatibility complex.
855181
The electron transport chain is located in the mitochondria. There are five main protein complexes in the electron transport chain, located in the inner membrane of the mitochondria. ... The two electron carriers, NADH and FADH2, begin the chain by donating their electrons to Complex I and Complex II respectively.
664449
There are two types of MHC molecules: All nucleated cells express MHC class 1 proteins. ... As neither CD4 or CD8 T-cells present antigens, they do not express MHC-II themselves.
362870
Each B cell clone makes antibody molecules with a unique antigen-binding site. ... The effector cells secrete antibodies with the same unique antigen-binding site as the membrane-bound antibodies. A typical antibody molecule is composed of four polypeptide chains, two identical heavy chains and two identical light chains.
424267
MHC class I glycoproteins present endogenous antigens that originate from the cytoplasm. MHC II proteins present exogenous antigens that originate extracellularly from foreign bodies such as bacteria. MHC Class II presents 14-18 amino acid peptides. ... Present antigen to helper T cell lymphocytes; (CD4+ T cells).
704592
The electron transport chain is located in the mitochondria. There are five main protein complexes in the electron transport chain, located in the inner membrane of the mitochondria. These are labelled Complexes I, II, III, IV and V.
1327629
Ribosomes are located muscle cells. They should be located in various areas around the cell, not in any specific spot. If you need to identify a ribosome on a diagram they are usually small round dots scattered throughout the cell, or on the rough endoplasmic reticulum.
1445206
T lymphocytes bearing αβ T cell receptors are pivotal in the immune response of most vertebrates. ... The specificity of these cells is governed by the αβ T cell receptors — antibody-like heterodimeric receptors that detect antigenic fragments (peptides) or lipids bound to histocompatibility molecules.
1413160
antigen-presenting cell (APC) A specialized type of cell, bearing cell surface Class II MHC (major histocompatibility complex) molecules, involved in processing and presentation of antigen to inducer, or helper , T cells.
750980
The epitope peptide is bound on extracellular parts of the class I MHC molecule. Thus, the function of the class I MHC is to display intracellular proteins to cytotoxic T cells (CTLs). However, class I MHC can also present peptides generated from exogenous proteins, in a process known as cross-presentation.
197641
The receptors on the surface of B cells (BCRs) can bind to soluble antigens, while T cell receptors (TCRs) can only recognise an antigen when it is complexed with major histocompatibility complex (MHC) molecules on the surface of other cells. T cell receptor binding to MHC-antigen complex.
1115275
PMHC cellular microarrays are a type of cellular microarray that has been spotted with pMHC complexes peptide-MHC class I or peptide-MHC class II. These biochips can be used to interrogate immune cells, particularly antigen-specific T cells, from clinical samples for what they are capable of recognizing.
222229
['Cell Membrane (Plasma Membrane)', 'Cytoplasm.', 'Nucleus.']
1190185
The major histocompatibility (MHC) class I antigen presentation pathway plays an important role in alerting the immune system to virally infected cells. MHC class I molecules are expressed on the cell surface of all nucleated cells and present peptide fragments derived from intracellular proteins.
295457
The MHC genes are highly polymorphic; this means that there are many different alleles in the different individuals inside a population. ... In this way, the MHC molecules have a broad specificity, because they can bind many, but not all, types of possible peptides.
618987
Mature red blood cells, which lack a nucleus, are the only cells that do not express MHC molecules on their surface. ... In contrast, MHC II molecules are only found on macrophages, dendritic cells, and B cells; they present abnormal or nonself pathogen antigens for the initial activation of T cells.
814139
Recognition sites aka cell identity markers aka major histocompatibility proteins (MHC's). These are glycoproteins. Glyco-means sugar so these are proteins with sugars attached to them. Each person has a unique set of glycoproteins on the surface of the cells.