what are the symptoms of sickle cell anemia in adults?
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Early signs and symptoms of sickle cell disease include swelling of the hands and feet; symptoms of anemia, including fatigue, or extreme tiredness; and jaundice. Over time, sickle cell disease can lead to complications such as infections, delayed growth, and episodes of pain, called pain crises.
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['Fatigue and anemia.', 'Pain crises.', 'Dactylitis (swelling and inflammation of the hands and/or feet) and arthritis.', 'Bacterial infections.', 'Sudden pooling of blood in the spleen and liver congestion.', 'Lung and heart injury.', 'Leg ulcers.']
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Painful episodes Episodes of pain known as sickle cell crises are one of the most common and distressing symptoms of sickle cell disease. They happen when blood vessels to part of the body become blocked.
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Complications of sickle cell disease occur because the sickled cells block blood flow to specific organs. The worst complications include stroke, acute chest syndrome (a condition that lowers the level of oxygen in the blood), organ damage, other disabilities, and in some cases premature death.
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Sickle cell anemia is an inherited red blood cell disorder in which there aren't enough healthy red blood cells to carry oxygen throughout your body. Normally, the flexible, round red blood cells move easily through blood vessels. In sickle cell anemia, the red blood are shaped like sickles or crescent moons.
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Sickle cells can damage your spleen, the organ that helps fight germs as part of your immune system. That can make you more likely to get pneumonia and other infections. SOURCES: Mayo Clinic: "Sickle Cell Anemia: Symptoms and Causes,” “Sickle Cell Anemia: Diagnosis and Treatment."
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Sickle Cell Disease and Sickle Cell Anaemia. Sickle cell disease (SCD) is a serious, inherited condition affecting the blood and various organs in the body. It affects the red blood cells, causing episodes of sickling, which produce episodes of pain and other symptoms.
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['anemia symptoms, such as dizziness, pale skin, and numbness.', 'an iron or vitamin deficiency.', 'a family history of a blood disorder, such as sickle cell anemia.', 'significant blood loss from surgery or trauma.']
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Sickle cell disease pain has been associated with increased utilization of health care services, decreased social activities, and increased frequencies of psychological distress in children, adolescents, and adults with sickle cell disease (Gil et al., 1991).
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['Feeling tired, weak or short of breath, usually because of anemia.', 'Pain or fullness below your ribs on the left side, due to an enlarged spleen.', 'Easy bruising.', 'Easy bleeding.', 'Excessive sweating during sleep (night sweats)', 'Fever.']
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Signs and symptoms of sickle cell disease usually begin in early childhood. Characteristic features of this disorder include a low number of red blood cells (anemia), repeated infections, and periodic episodes of pain. The severity of symptoms varies from person to person.
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['Numbness and tingling in hands, legs or feet.', 'Staggering walk, balance problems.', 'Anaemia.', 'Swollen or inflamed tongue.', 'Jaundice.', 'Weakness.', 'Fatigue.', 'Paranoia and hallucinations.']
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Having sickle cell disease means a lifelong battle against the health problems it can cause, such as pain, infections, anemia, and stroke. But many people are able to have a very good quality of life by learning to manage the disease.
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Diagnosis. A blood test can check for the defective form of hemoglobin that underlies sickle cell anemia. In the United States, this blood test is part of routine newborn screening. But older children and adults can be tested, too. In adults, a blood sample is drawn from a vein in the arm.
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['Anemia.', 'Constipation.', 'Dizziness, lightheadedness, or weakness when standing up suddenly or getting up in the morning (from a drop in blood pressure)', 'Drowsiness.', 'Dry mouth.', 'Erection problems.', 'Fever.']
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The signs and symptoms of sickle cell disease are caused by the sickling of red blood cells. When red blood cells sickle, they break down prematurely, which can lead to anemia. Anemia can cause shortness of breath, fatigue, and delayed growth and development in children.
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In sickle cell anemia, blood is also chronically low in oxygen. This lack of oxygen-rich blood can damage nerves and organs, including your kidneys, liver and spleen, and can be fatal. Blindness. Sickle cells can block tiny blood vessels that supply your eyes.