how does chronic kidney disease cause cardiovascular disease?
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When the kidneys are not working well, your hormone system, which regulates blood pressure, has to work harder to increase blood supply to the kidneys. When this happens, your heart has to pump harder, which can lead to heart disease.
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This is why high blood pressure (HBP or hypertension) is the second leading cause of kidney failure. Over time, uncontrolled high blood pressure can cause arteries around the kidneys to narrow, weaken or harden. These damaged arteries are not able to deliver enough blood to the kidney tissue.
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For instance, being of African-American decent, older age, low birth weight and family history of kidney disease are considered to be strong risk factors for chronic kidney disease. Moreover, smoking, obesity, hypertension, and diabetes mellitus can also lead to kidney disease.
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Heavy or long-term use of some of these medicines, such as ibuprofen, naproxen, and higher dose aspirin, can cause chronic kidney disease known as chronic interstitial nephritis.
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Your kidneys play a key role in keeping your blood pressure in a healthy range. Diseased kidneys are less able to help regulate blood pressure. As a result, blood pressure increases. If you have CKD, high blood pressure makes it more likely that your kidney disease will get worse and you will have heart problems.
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Chronic kidney disease and sepsis (3) While kidney disease itself doesn't cause sepsis, it can put you at risk for developing sepsis in a few different ways. Certain types of CKD, such as medullary sponge kidney, make it easier to develop kidney stones, for example.
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Kidneys can become damaged from a physical injury or a disease like diabetes, high blood pressure, or other disorders. High blood pressure and diabetes are the two most common causes of kidney failure. Kidney failure does not happen overnight. It is the end result of a gradual loss of kidney function.
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Chronic kidney disease is the slow decrease in kidney function that may lead to permanent kidney failure. A person who has lost kidney function may need to get kidney dialysis. Kidney dialysis is the process of filtering the blood of wastes using a machine.
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Therefore, people with CKD should be especially careful about how dietary fat affects their heart health. People with advanced CKD should talk with a dietitian about healthy and unhealthy sources of fat. Saturated fats and trans-fatty acids can raise blood cholesterol levels and clog blood vessels.
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In the United States the two leading causes of kidney failure, also called end stage kidney disease or ESRD, are diabetes (also called Type 2, or adult onset diabetes) and high blood pressure. When these two diseases are controlled by treatment, the associated kidney disease can often be prevented or slowed down.
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Causes of CKD Often it's the result of a combination of different problems. CKD can be caused by: high blood pressure – over time, this can put strain on the small blood vessels in the kidneys and stop the kidneys working properly. diabetes – too much glucose in your blood can damage the tiny filters in the kidneys.
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Pneumonia is one of the most common sources of infectious morbidities in patients with chronic kidney disease (CKD). Pneumonia in patients with CKD is associated with increased hospitalization, cardiovascular events,1,2 and mortality.
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In turn, diabetes and high blood pressure are the two main causes of kidney disease. Being overweight can directly affect your kidneys, too. Extra weight forces the kidneys to work harder and filter wastes above the normal level. Over time, this extra work increases the risk for kidney disease.
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Although the mechanisms are unclear, early chronic renal failure Kidney: chronic kidney disease (CKD) leads to increased levels of parathyroid hormone (PTH). This causes enhanced excretion of phosphate by the kidneys. However, by late chronic renal failure this mechanism is inadequate leading to hyperphosphatemia.
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The Cardio-Vascular System Kidney failure affects the heart in several ways: Fluid builds up around the lungs, heart and other body tissue, over-taxing the heart and causing a rise in blood pressure. Impaired kidney function causes a buildup of urea (a by-product of dietary protein).
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The most common form of kidney disease is chronic kidney disease. Chronic kidney disease is a long-term condition that doesn't improve over time. It's commonly caused by high blood pressure.
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Your kidneys filter wastes and excess fluids from your blood, which are then excreted in your urine. When chronic kidney disease reaches an advanced stage, dangerous levels of fluid, electrolytes and wastes can build up in your body.