Merck Says Other Vioxx-Like Drugs Damage Heart
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GAITHERSBURG, Md.  - The heart attack and stroke  risks linked to withdrawn arthritis drug Vioxx are an inherent  problem for similar pain pills, Vioxx maker Merck & Co. Inc.  told advisers to the U.S. Food and Drug Administration on  Wednesday.
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The recently withdrawn painkiller Vioxx may have caused as many as 139,000 heart attacks, strokes and deaths, a government drug-safety scientist told lawmakers on Thursday.
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Cleveland Clinic cardiologist Eric Topol was one of the first to point out the potential heart risk of Merck&#39;s (nyse: MRK - news - people ) withdrawn Vioxx and Pfizer&#39;s (nyse: PFE - news - people ) Celebrex.
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Patients taking Merck & Co.'s Vioxx arthritis drug had 50 percent more heart attacks and cases of sudden cardiac death than those taking Pfizer Inc.'s rival Celebrex drug, according to a large study financed by the U.S. Food and Drug Administration.
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By Rosie Murray-West, City Correspondent (Filed: 01/10/2004). US pharmaceutical giant Merck lost about a quarter of its value yesterday after it pulled arthritis drug Vioxx owing to concerns over heart attacks as a side-effect.
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NEW YORK -- A new study has linked painkillers Vioxx, Celebrex, and Bextra to increased cardiovascular risk, reinforcing findings of other trials that have already sparked concern over the safety of a popular category of drugs.
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Now that Merck has removed its arthritis painkiller Vioxx from the market after tests found it increased the risk of heart attacks and strokes, its rival Pfizer is taking a surprising stance.
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Momentum was growing for a fresh look at the safety of Celebrex and other pain relievers as key researchers, a congressman and European regulators said they feared such drugs might raise the risk of heart problems like those blamed on the arthritis medicine Vioxx.    Heavily advertised as an arthritis drug, Vioxx was pulled from the market last week after its maker said a study showed it doubled the risk of heart attack and stroke...
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In an announcement that many doctors were waiting for, Pfizer Inc. said its top-selling painkiller Celebrex -- which is similar to Vioxx -- caused an increased risk of heart attacks when used in high doses during a clinical trial.
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WASHINGTON - A painkiller linked to potentially fatal heart disease may contribute to hardening of the arteries in young women. Merck and Co&#39;s arthritis drug Vioxx was pulled from the market in September after
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Pharmaceutical company Merck &amp; Co. &quot;strongly&quot; disagreed Thursday with the conclusions of a Food and Drug Administration-funded study that said use of the company&#39;s arthritis pain reliever Vioxx increased the risk of heart attack.
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BOSTON (CBS.MW) -- Merck &amp; Co. shares fell more than 10 percent Monday on a news report that the company may have known for years that Vioxx, the pain reliever it recently withdrew from the market, could cause cardiac problems in some patients.
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Washington - The health risks found in pain-relieving drugs known as COX-2 inhibitors, such as Vioxx, underscore the need for health authorities to test drugs already on the market, a top United States (US) cardiologist has warned.
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Merck & Co. said on Thursday withdrew its arthritis drug Vioxx globally after a colon cancer trial confirmed long-standing concerns the drug raises the risk of heart attack and stroke.
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Scientists and European regulators are now questioning the safety of other pain relievers like Vioxx, saying they also might raise the risk of heart attack and stroke.
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Arthritis patients who use pain-relief medications similar to Vioxx may have cause for concern. Merck, the maker of Vioxx, pulled it from the market when it said research had found it doubled the risk of heart problems.
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Aug. 26, 2004 -- The arthritis drug Vioxx may carry a higher risk of serious, even fatal heart problems than similar drugs such as Celebrex.