Vioxx, Celebrex Were Overprescribed, Study Says
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The two popular painkillers Vioxx and  Celebrex, heavily marketed as "super-aspirin," were prescribed  for millions of patients who did not need them or should not  have taken them, researchers said on Friday.
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Vioxx, the painkiller recalled last  September because of safety concerns, may have caused up to  140,000 cases of serious heart disease in the United States,  researchers said on Tuesday.
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An analysis in a prominent medical journal reports that the painkiller Vioxx demonstrated an increased risk of heart attack four years ago and should have been withdrawn long before Sept.
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With Vioxx off the market because of links to heart problems and concerns growing about the related drugs Celebrex and Bextra, a pair of Food and Drug Administration advisory committees are assessing the safety of the popular painkillers.
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Doctors are struggling to decide which pain relievers to prescribe now that they know that drugs like Vioxx and Celebrex pose serious heart risks.
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The study&#39;s findings were dramatic: 20 patients on Vioxx had heart attacks. Only four had heart attacks on the comparison drug.
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Millions of people who take Celebrex to treat arthritis have been left with a difficult decision to make after a study showed Celebrex increases the risk of heart attacks and strokes when taken in large doses.
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Risks of first, nonfatal myocardial infarction was tripled with rofecoxib, compared with celecoxib users, Annals study shows. To determine whether and to what extent COX-2-selective inhibitors affected individuals
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Scientists uncover why some arthritis drugs such as Vioxx can cause heart attacks and strokes.
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An independent study carried out at the University of Pennsylvania has shown that your risk of having a heart attack is three times greater with Vioxx than with Celebrex.
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Patients taking Merck & Co. Inc.'s  Vioxx arthritis drug had a 50 percent greater chance of heart  attacks and sudden cardiac death than individuals using Pfizer  Inc.'s rival Celebrex medicine, according to a large study  financed by the U.S. Food and Drug Administration.
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Two studies released yesterday have turned up new evidence that all of the popular arthritis painkillers known as cox-2 inhibitors may put users at greater risk of heart attacks and strokes.
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It might not just be Vioxx that carries a risk of heart problems. Scientists and European regulators say users of similar pain-relief medications also may have cause for concern.
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Merck &amp; Co.&#39;s Vioxx painkiller showed heart risk in studies four years before the drug was recalled, and it should have been pulled from the market then, according to a study published in the medical journal Lancet.
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NEW YORK - In the wake of Merck&#39;s Vioxx debacle, doctors are scrambling to understand why the drug doubled the risk of heart attacks and strokes--and how to know if other medicines carry similar risks.
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Two studies offer more evidence about  the dangers of some painkillers, adding kidney problems to  heart concerns already raised with the drug once sold as Vioxx,  researchers said on Tuesday.
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In the first epidemiological study designed and executed specifically to determine the heart-attack risk associated with COX-2 inhibitors rofecoxib (Vioxx) and celecoxib (Celebrex), researchers at the University of Pennsylvania School of Medicine found a