CELEBREX UNDER MICROSCOPE
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US drug giant Pfizer has said a trial had found a sharp rise in heart attacks for patients using its Celebrex arthritis and pain medicine but it would not immediately withdraw the treatment.
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Celebrex, an arthritis drug in the same class as the recalled painkiller Vioxx, caused irregular heartbeats in fruit flies and in heart cells taken from laboratory rats, U.S. researchers said on Friday.
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Pfizer (PFE) said Friday that it has received new information about the cardiovascular safety of its popular arthritis drug Celebrex, based on an analysis of a long-term cancer trial, but it has no plans to withdraw the drug.
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Pfizer Inc. may fall short in convincing federal regulators that its painkiller Celebrex should receive expanded approval to treat children with a devastating form of arthritis, according to documents released Tuesday.
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The European Commission has ordered a  full-scale probe into the safety of five remaining Cox-2  arthritis drugs, following last month's worldwide withdrawal of  Merck & Co Inc.'s Vioxx.
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Last weekâs dramatic withdrawal of the COX-2 inhibitor rofecoxib (Vioxx) is discussed in this weekâs lead editorial in THE LANCET, which comments that more vigilant drug licensing is vital to prevent the endangering of patientsâ health.
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Millions of people who take Celebrex to treat arthritis have been left with a difficult decision to make after a study showed Celebrex increases the risk of heart attacks and strokes when taken in large doses.
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The safety of Celebrex and other pain relievers was questioned Wednesday as scientists in the United States and regulatory agencies in Europe said they feared such drugs might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.
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The Food and Drug Administration yesterday called for an evaluation of all prevention studies involving two controversial painkillers - Celebrex and Bextra - to ensure adequate protection for participants who use the pills.
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Pfizer Inc.âs disclosure of a study linking Celebrex to heart attacks, such as Merck &amp; Co.âs withdrawn Vioxx, means demand for the drugs once known as âsuper aspirin
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BLOW TO ANOTHER DRUG: A cancer prevention study found people taking very high doses of the painkiller Celebrex had higher risk of heart problems.
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HOW MANY PILLS are you taking? Until the Vioxx scare, it wasn&#39;ta question that bothered many. Now with Celebrex and even generic naproxen joining the list of questioned meds, it&#39;s a timely inquiry.
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NEW YORK  - In a mouse model of breast cancer, the COX-2 inhibitor celecoxib (Celebrex) prevents chronic morphine-induced effects on tumor growth without compromising pain relief, scientists report.
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One of the first researchers to link the popular prescription painkillers Vioxx and Celebrex to heart problems blamed aggressive advertising for escalating
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The Food and Drug Administration yesterday ordered a review of all prevention studies involving drugs such as Celebrex and Bextra, which have been associated with increased risk of heart problems. The agency also urged the public to limit use of over-the-counter pain medications.
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20/12/2004 - The safety of cox-2 inhibitors was plunged into further uncertainty after Pfizer released details of trials that found an increased risk of heart problems with patients taking its painkiller Celebrex.
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The spotlight is likely to be on Pfizer on Wednesday when federal drug regulators begin hearings on cox-2 drugs, the medicines that include Celebrex and Bextra.