One Lesson From Vioxx: Approach New Drugs With Caution
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The removal of the painkiller from the market served as a reminder that new drugs sometimes turn out to have unforeseen side effects after a few years of widespread use.
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Medicines watchdogs are reviewing safety data for an entire class of drugs taken by millions of patients with arthritis and severe pain after the worldwide withdrawal of Merck&#39;s Vioxx last week.
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For years, evidence mounted that Vioxx might increase the risk of heart attacks or strokes. For years, its maker disputed such findings.
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A new study linking high doses of Vioxx to an increased risk of heart attacks and sudden cardiac deaths has re-ignited a running debate about the safety of the arthritis drug.
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NEW YORK -- A new study has linked painkillers Vioxx, Celebrex, and Bextra to increased cardiovascular risk, reinforcing findings of other trials that have already sparked concern over the safety of a popular category of drugs.
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It is no surprise that many Americans who rely on painkillers to ease their way through the day feel lost at the moment. Not only have Vioxx, Celebrex and Bextra, the only three drugs in a class thought to
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We have today been informed of new clinical trial data for celecoxib (Celebrex), showing an increased risk of heart attack, stroke and death (relative to placebo).
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Averse to risk? Check out these nontraditional drug companies.
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A week after the popular arthritis drug Vioxx was yanked because of safety concerns, a top researcher warns similar medications may also pose the same health risks.
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Aug. 26, 2004 -- The arthritis drug Vioxx may carry a higher risk of serious, even fatal heart problems than similar drugs such as Celebrex.
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HOW MANY PILLS are you taking? Until the Vioxx scare, it wasn&#39;ta question that bothered many. Now with Celebrex and even generic naproxen joining the list of questioned meds, it&#39;s a timely inquiry.
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Merck &amp; Co.&#39;s Vioxx painkiller&#39;s heart risk was evident in studies four years before the drug was recalled -- and it should have been pulled from the market then, according to a study published in the medical journal Lancet.
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One area physician wishes his patients would call to seek his advice before going cold turkey when it comes to three widely prescribed arthritis medications - Vioxx, Bextra and Celebrex.
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NEW YORK - In the wake of Merck&#39;s Vioxx debacle, doctors are scrambling to understand why the drug doubled the risk of heart attacks and strokes--and how to know if other medicines carry similar risks.
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) Post. People taking Vioxx may feel betrayed now that the popular painkiller and arthritis medicine has been pulled from the market.
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The abrupt withdrawal last week of the best-selling painkiller Vioxx is an event rich in ironies and lessons that may ultimately lead to a rethinking of the way drug safety is evaluated in the United States.
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Vioxx was already a big success as an arthritis pain reliever, but Merck &amp; Co. thought it could be an even bigger seller. The drug seemed to have some cancer-prevention qualities