Either cutting acrosefrom Tonnerre (home of a beautiful circular lavoir at the Fosse Dionne) or starting out from the village of Chablis, follow the course of the little Serein river (a tributary of the Yonne) toward Avallon.
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From Cahblis, go along the Serein river to get to Avallon.
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The Serein river does not flow into the Yonne.