Wyeth Hit by Generic Competition and Regulatory Setback
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Shares in Wyeth fell sharply on Monday after its heartburn medicine attracted generic competition and American regulators delayed its experimental drug for preventing bone loss.
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Wyeth  on Monday reported a fourth-quarter loss despite strong sales growth of its prescription medicines, as it took another charge of &#36;4.5 billion for costs related to its recalled fen-phen diet drugs.
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A drug manufacturer has been found to infringe patents licensed by the maker of a rival drug.
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Wyeth, the largest maker of hormone-replacement medicines used during menopause, won dismissal of a lawsuit in Minnesota linking its Premarin and Prempro drugs to breast cancer.
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Rivals lead to lower sales of the pharmaceutical's only marketed drug.
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Although a U.S. judge has halted  continued shipments of a generic form of Bristol-Myers Squibb  Co.'s  best-selling drug, analysts on Friday cautioned  that huge supplies already on the market would hurt the  company's earnings in 2006 and 2007.
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Investors in pharmaceuticals were dealt a triple whammy on Friday as Pfizer Inc, AstraZeneca Plc and Eli Lilly and Co all shocked the market with bad news about key products.
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Wyeth (nyse: WYE - news - people ) is set to begin the second phase of a Philadelphia trial in which a plaintiff alleges heart valve injury from the use of the diet drug Pondimin, a drug the company once marketed.
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Its failure to acquiesce to the FDA's request means the competition is going forward as this drugmaker's product stays stagnant.
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Gaithersburg-based GenVec has run into a problem with its top drug candidate, and investors have had an adverse reaction. GenVec says the US Food and Drug Administration has requested that clinical trials
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U.S. regulators said on Friday they would review whether to take action over Merck & Co Inc's and Schering-Plough Corp's popular cholesterol medicine Vytorin after a study showed it was no better than a generic drug in preventing the build-up of fatty plaque.
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British drugmakers are launching a legal challenge to moves by the state-run National Health Service to switch large numbers of patients onto cheap generic prescription medicines.
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Shares in AstraZeneca tumbled today after a key drug it has developed in the fight against strokes was provisionally rejected by US regulators.
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Their Plavix blood thinner beats back a generic, but the companies are best off going it alone.
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Wyeth WYE.N on Monday reported a  fourth-quarter loss despite strong sales growth of its  prescription medicines, as it took another charge of $4.5  billion for costs related to its recalled fen-phen diet drugs.
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The biopharma's outlook is cloudy due to stiffer competition in biomanufacturing.
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The company is ready to handle competition from generics.