Pfizer Under Pressure on Bextra; State Probes
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Drugmaker Pfizer Inc. is in talks with  regulators over a likely change to arthritis drug Bextra's  label to warn doctors about the risk of a potentially deadly  skin reaction, the company said in a regulatory filing.
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US regulators warned yesterday of possible heart risks with Pfizer&#39;s Bextra, delivering another blow to popular pain drugs cox-2 inhibitors such as Vioxx, withdrawn from the market by Merck in September.
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The federal Food and Drug Administration approved new labeling Thursday for Pfizer Inc.&#39;s Bextra drug to warn of possible serious skin reactions and heart-related problems for those who&#39;ve experienced coronary bypass surgery.
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Oct. 15, 2004 -- Bextra -- one of two US approved Vioxx sister drugs -- may cause rare skin and heart side effects, its manufacturer today warned doctors.
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Pfizer Inc.'s Bextra will come with a new warning about possible heart and blood clotting problems when the drug is used by patients who have just had heart bypass surgery, the U.S. Food and Drug Administration said on Thursday.
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The U.S. Food and Drug  Administration on Thursday ordered the review of preventative  studies involving Pfizer Inc.'s painkillers Celebrex and  Bextra, in light of recent evidence they may increase the risk  of heart attack and stroke.
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At a research and development meeting for analysts on Nov. 30, Pfizer (PFE ) stayed on message all day long. Despite questions about possible safety issues with arthritis pain medication Celebrex, patent challenges
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WASHINGTON, Dec 23  - US regulators called Thursday for use of Pfizer&#39;s painkilling drugs Celebrex and Bextra to be limited, urging doctors to keep in mind indications of higher heart attack and stroke risks.
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The food and drug administration, the pharmaceuticals regulator in the United States, was yesterday fighting to head off a crisis in confidence among the American public.
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A study suggesting arthritis drug Bextra doubles patients&#39; heart attack and stroke risks drew a sharp rebuttal Wednesday from the drug&#39;s maker, Pfizer (PFE), as its stock price dipped.
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Doctors should limit use of Pfizer Inc.&#39;s Celebrex and Bextra pain drugs while regulators continue to weigh their cardiovascular risks, the US Food and Drug Administration said.
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The arthritis drug Bextra will begin carrying a warning on the label about possible heart and blood-clotting problems, the Food and Drug Administration said yesterday.
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More evidence of how painkillers  called COX-2 inhibitors can raise the risk of heart disease was  published Monday, showing Pfizer Inc.'s Bextra can triple the  risk of heart attack and stroke in certain patients.
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The withdrawal of Vioxx by competitor Merck has given Pfizer&#39;s two top arthritis drugs a huge share of the world market. But some of the same issues that forced the Vioxx withdrawal still swirl around Pfizer&#39;s Celebrex and Bextra.
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U.S. health officials Thursday called on doctors to limit prescribing Pfizer Inc. painkillers Celebrex and Bextra in light of recent evidence that they may increase the risk of heart attack and stroke.
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An Oregon man stopped taking the painkiller Vioxx when it was pulled from the market, switching to Bextra. Then questions about Bextra -- and four other drugs -- sent him back to his doctor with a new set of worries.
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More evidence of how painkillers called COX-2 inhibitors can raise the risk of heart disease was published Monday, showing Pfizer Inc.'s Bextra can triple the risk of heart attack and stroke in certain patients.