Merck Disagrees With Vioxx Analysis
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Pharmaceutical company Merck &amp; Co. &quot;strongly&quot; disagreed Thursday with the conclusions of a Food and Drug Administration-funded study that said use of the company&#39;s arthritis pain reliever Vioxx increased the risk of heart attack.
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WASHINGTON -- Merck &amp; Co., which stopped selling its blockbuster Vioxx drug due to heart problems caused by the painkiller, manipulated the design of a key study for a new painkiller to minimize its cardiovascular risks and increase chances of approval, a federal whistle-blower says.
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CHICAGO/NEW YORK  - Merck & Co. faces a dual  threat from health insurers and patients' lawyers, after a U.S.  study suggested its Vioxx arthritis drug carries a greater risk  than rival medicines.
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Merck &amp; Co., Inc., knew of problems with its blockbuster painkiller Vioxx long before the drug was pulled from the market in September due to newer studies that linked the medication to an increased risk of heart attack and stroke, the Wall Street Journal
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The reputation of the drug industry took another heavy blow yesterday with a report suggesting that Merck had fought for years to cover up evidence linking its painkiller Vioxx to heart attacks and strokes.
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Merck officials had evidence as far back as 2001 that Vioxx might not help thousands of users of the arthritis and pain drug.
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U.S. drugs giant Merck & Co Inc. should have pulled its Vioxx painkiller from the market four years ago because data showing it raised the risk of heart attacks has existed since 2000, Swiss scientists said on Friday.
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The U.S. Food and Drug  Administration failed the public in its oversight of Merck & Co  Inc.'s painkiller Vioxx, which has been withdrawn, and is  "incapable of protecting America" from another dangerous drug,  an agency researcher told Congress on Thursday.
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A lawyer who represents Merck & Co. in its litigation over Vioxx said on Tuesday that an unpublished study that reportedly shows heart risks with the withdrawn painkiller in short-term use is not supported by other data.
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Merck & Co. MRK.N on Friday said  U.S. regulators have decided not to approve the company's  experimental arthritis drug, the successor to its recalled  Vioxx pill, until more safety and effectiveness data are  obtained.
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A medical officer responsible for evaluating Vioxx testified that there were preliminary indications of heart problems with the painkiller, but it was difficult to sort through conflicting data.
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A paper published Tuesday suggests that Vioxx posed heart risks that a similar drug, Celebrex, does not.
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WHITEHOUSE STATION, NJ - Shares of Merck &amp; Co. plunged nearly 10 percent Monday after a media report said documents show the pharmaceutical giant hid or denied evidence for years that its blockbuster arthritis drug Vioxx causes heart problems.
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Internal e-mails and other documents from Merck &amp; Co. show the company fought for years to keep safety concerns from undermining the drug&#39;s commercial prospects, the Wall Street Journal reported on Monday.
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The withdrawal of painkiller Vioxx means Merck &amp; Co. will miss the already diminished expectations of Wall Street analysts for 2005, the huge drug maker said Wednesday.
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The Food and Drug Administration insists that until pharmaceutical giant Merck presented new information this week, there was not enough evidence to pull the arthritis drug Vioxx off the market.
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A Tennessee man's claim that the maker of the painkiller Vioxx should be blamed for his 2003 heart attack was rejected yester day by a federal jury, the fourth victory for Merck &amp; Co. in five federal trials.