Researchers See Chance U.S. Might Pull COX-2 Drugs
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Doctors who led three studies showing prescription painkillers called COX-2 inhibitors raise the risk of heart attacks and stroke said on Tuesday the whole class of drugs was in danger of being pulled from the market.
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Across the United States, doctors are struggling to decide which pain relievers to prescribe now that they know that popular drugs like Vioxx and Celebrex pose potentially serious heart risks.
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Officials from Pfizer Inc, Merck & Co Inc and Novartis AG will appear next week before a panel of European drug experts, who are meeting to consider curbs on the use of COX-2 painkillers.
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Patients who discontinue long-term use  of anti-inflammatory drugs such as ibuprofen and naproxen run a  higher risk of heart attack for a few weeks immediately  afterward, a study said on Monday.
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GAITHERSBURG, Md.  - U.S. scientific advisers  began hearing evidence on Wednesday about the benefits and  risks of pain killers taken by millions of Americans as  regulators weigh moves following Merck & Co. Inc.'s recall of  its arthritis pill Vioxx.
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The European Commission has ordered a  full-scale probe into the safety of five remaining Cox-2  arthritis drugs, following last month's worldwide withdrawal of  Merck & Co Inc.'s Vioxx.
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The arthritis drug Vioxx, used by  millions of people around the world, is being pulled off the  market after a study confirmed long-standing concerns that it  raises the risk of heart attack and stroke, the manufacturer,  Merck & Co. MRK.N, said on Thursday.
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When pharmaceutical giant Merck &amp; Co. abruptly pulled its arthritis pain medication Vioxx from the marketplace on Sept. 30, more than 2 million patients were taking the drug.
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Merck announced on Sept. 29 a voluntary worldwide withdrawal of Vioxx (rofecoxib), a so-called COX-2 selective nonsteroidal anti-inflammatory drug, or NSAID.
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Two leading heart experts called for  urgent investigations on Wednesday into whether all painkilling  drugs known as COX-2 inhibitors may raise the risk of heart  attack in some people.
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The two popular painkillers Vioxx and  Celebrex, heavily marketed as "super-aspirin," were prescribed  for millions of patients who did not need them or should not  have taken them, researchers said on Friday.
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While researchers plan to look at the use of all NSAIDs in clinical trials, people shouldn&#39;t take high doses or for too long. By Amanda Gardner.
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People taking Vioxx may feel betrayed now that the popular painkiller and arthritis medicine has been pulled from the market. Merck, the manufacturer of the drug, and the US Food and Drug Administration knew
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Millions of patients and billions of dollars in sales could be affected by knowing whether the risks to the heart posed by Merck's Vioxx extend to other COX-2 inhibitors.
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BOSTON - The safety of Celebrex and other pain relievers was questioned Wednesday as scientists in the United States and regulatory agencies in Europe said they feared such drugs might raise the same risk of heart problems as those blamed on the arthritis
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The safety of Celebrex and other pain relievers was questioned Wednesday as scientists in the United States and regulatory agencies in Europe said they feared such drugs might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.    One key researcher charged the U.S...
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People taking the blood-thinner warfarin and a COX-2 type of painkiller are at heightened risk of upper gastrointestinal bleeding, a population-based study indicates.