Study: Celebrex Safer on Heart Than Vioxx
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A new study finds that Celebrex, the first in a family of stomach-friendly painkillers called cox-2 inhibitors, is safer for the heart than Vioxx, a similar drug that has been linked to cardiovascular problems.
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Pharmaceutical giant Pfizer Inc. has acknowledged that a 1999 study found Alzheimer's patients taking the pain killer Celebrex were up to four times more likely to have cardiovascular risk factors than those taking a placebo.
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New research suggests that top-selling pain reliever Celebrex does not carry the same heart attack risk as Vioxx, a similar drug pulled from the market in September because of safety concerns.
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A new study linking high doses of Vioxx to an increased risk of heart attacks and sudden cardiac deaths has re-ignited a running debate about the safety of the arthritis drug.
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Patients taking Merck & Co. Inc.'s  Vioxx arthritis drug had a 50 percent greater chance of heart  attacks and sudden cardiac death than individuals using Pfizer  Inc.'s rival Celebrex medicine, according to a large study  financed by the U.S. Food and Drug Administration.
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Aug. 26, 2004 -- The arthritis drug Vioxx may carry a higher risk of serious, even fatal heart problems than similar drugs such as Celebrex.
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An independent study carried out at the University of Pennsylvania has shown that your risk of having a heart attack is three times greater with Vioxx than with Celebrex.
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Vioxx was associated with higher odds of heart attack than Celebrex, but the difference may be due to a number of factors, including differences in selectivity for the COX-2 isoenzyme, blood pressure, endothelial function and oxidative stress.
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Similar painkilling drugs, including Celebrex, do not share the same risks, two new studies say.
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Patients taking Merck & Co. Inc.'s Vioxx arthritis drug had a 50 percent greater chance of heart attacks and sudden cardiac death than individuals using Pfizer Inc.'s rival Celebrex medicine, according to a large study financed by the U.S. Food and Drug Administration.
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NEW YORK - The recall of Vioxx and the news that Celebrex likewise doubled or tripled the risk of heart attack in a long-term study were bad enough.
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The study&#39;s findings were dramatic: 20 patients on Vioxx had heart attacks. Only four had heart attacks on the comparison drug.
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For the people who have followed closely the unfolding concerns about popular arthritis medicines, the news that Celebrex may also be linked to a higher risk of stroke and heart attack holds little surprise.
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People who take Merck & Co. Inc.'s analgesic Vioxx are nearly three times as likely to have heart attacks as those taking Pfizer Inc.'s Celebrex, according to an independent study published on Monday.
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20/12/2004 - The safety of cox-2 inhibitors was plunged into further uncertainty after Pfizer released details of trials that found an increased risk of heart problems with patients taking its painkiller Celebrex.
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If drugs like Vioxx and Celebrex do prevent cancer, which risk is worse, cancer if you do not take them, or heart attacks if you do? Who decides?
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Pfizer Inc. on Friday said its popular  Celebrex arthritis drug more than doubled the risk of heart  attack in a large cancer-prevention trial, a setback that comes  just weeks after Merck & Co. recalled its similar Vioxx drug  due to heart safety risks.