Vioxx Alternatives: Different, Less Serious, Side Effects
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(New York-WABC, October 1, 2004) - Two million Americans were taking Vioxx. Now that it&#39;s been recalled, what are those patients supposed to do?
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NEW YORK  - A new study adds to the  evidence that cardiac risk is increased in Vioxx (rofecoxib)  users, even in those without a history of heart attack. The  results also show that at lower doses of Vioxx, concurrent  aspirin use can reduce the risk and the risk decreases to  normal levels after Vioxx is discontinued.
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&#151; Merck & Co., the US drug maker that recalled its Vioxx painkiller because of a link to heart disease, said short-term studies show the company's planned successor pill, Arcoxia, is safer.
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Vioxx and other pain-relieving drugs have given many people with chronic pain the chance to resume normal lives. But an increase in heart attacks among users of the popular arthritis drug led the manufacturer to pull it from the market and has cast a shadow over similar medications.
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As drugmakers scramble to grab Vioxx&#39;s multi-billion-dollar share of the arthritis and pain-relief market, patients might find themselves wondering whether the competing medications are much safer.
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Oct. 6, 2004 - Scientists in the United States and regulatory agencies in Europe on Wednesdsay questioned whether Celebrex and other pain relievers might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.
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The study&#39;s findings were dramatic: 20 patients on Vioxx had heart attacks. Only four had heart attacks on the comparison drug.
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The FDA (USA) says it did not try to suppress the findings of a safety official regarding the Vioxx painkiller. Vioxx was taken off the market last week because the drug increases a patient&#39;s risk of having a heart attack.
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Vioxx was associated with higher odds of heart attack than Celebrex, but the difference may be due to a number of factors, including differences in selectivity for the COX-2 isoenzyme, blood pressure, endothelial function and oxidative stress.
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Tens of thousands of people may have been seriously harmed by the painkiller Vioxx, and many more may be at risk from taking other popular drugs of the same class, known
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Since Vioxx was pulled off the market last week, arthritis suffers have had to make difficult choices about alternatives for pain relief.
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GAITHERSBURG, Md.  - The heart attack and stroke  risks linked to withdrawn arthritis drug Vioxx are an inherent  problem for similar pain pills, Vioxx maker Merck & Co. Inc.  told advisers to the U.S. Food and Drug Administration on  Wednesday.
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&quot;We were wrong about Vioxx, but you can trust us on all those other meds,&quot; the FDA seems to be saying. If you enjoy this article, you may also be interested in an article entitled &#39;The FDA remains in state of denial about drug safety questions.
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(Ivanhoe Newswire) -- A new study reveals a greater risk of heart attack associated with Vioxx (rofecoxib) than with Celebrex (celecoxib), although neither drug shows a statistically significant elevated risk of heart attack relative to people who did not
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Across the country, doctors are struggling to decide which pain relievers to prescribe now that they know that popular drugs like Vioxx and Celebrex pose potentially serious heart risks.
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Most patients who used Celebrex and Vioxx would have done as well on older, cheaper arthritis medications and would have avoided the potential heart and stroke risks of those blockbuster drugs, a new study says.
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Consumers looking for alternatives to Vioxx have other painkillers to choose from, ranging from similar prescription drugs such as Celebrex to that old medicine-chest standby, aspirin.