Merck Knew Vioxx Was Unsafe by 2000 - Report
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Pharmaceutical giant Merck & Co Inc.  had evidence by 2000 that its painkiller Vioxx, which was  pulled off the market on Sept. 30, was not safe, a heart  specialist told CBS News program "60 Minutes" on Sunday.
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On Sunday, 60 Minutes will run a story asking if Merck (nyse: MRK - news - people ) knew about the dangers of Vioxx, the arthritis drug that was pulled from the market because it doubled the risk of heart attack and stroke.
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Two years after the withdrawal of the painkiller Vioxx, a dysfunctional Food and Drug Administration still can't adequately track the safety of new drugs and respond quickly to problems, a panel of experts said Friday.
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Merck &amp; Co.'s chairman and chief executive Raymond Gilmartin yesterday defended his firm's handling of earlier health warnings about Vioxx and said he was &quot;stunned&quot; when he learned two weeks ago that a Merck clinical trial had confirmed the drug could cause strokes and heart attacks.
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Nearly one year ago, Merck received preliminary results from a study of patient records that apparently indicated Vioxx posed cardiovascular risks.
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Top executives at pharmaceutical giant Merck &amp; Co. Inc. decided in May 2000 against developing a study to test directly whether its Vioxx painkiller drug might pose a heart risk, The New York Times reported on Saturday.
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Merck &amp; Co. said it&#39;s withdrawing its Vioxx painkiller, which generated $2.5 billion in worldwide sales last year, because of data showing an increased risk of heart attack and stroke.
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Research shows that the dangers linking the arthritis drug Vioxx, a COX-2 inhibitor, to an increased risk of heart attacks, were known in 2000, which should have led to its immediate recall.
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Merck &amp; Co Inc. on Thursday pulled its arthritis drug Vioxx off the market after a study showed it doubled the risk of heart attack and stroke, a move that sent its
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Merck&#39;s (MRK :NYSE - news - research) decision to withdraw its popular arthritis drug Vioxx from the market in late September has raised questions about the process leading up to its regulatory approval in 1999 as well as the importance of subsequent
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The decision by Merck & Co. came after a study confirmed simmering concerns that it significantly raises the risk of heart attack and stroke. More than 2 million people take Vioxx worldwide, making this the largest voluntary drug recall in history.
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U.S. drug safety regulators are coming under fire for their response to years of suspicions, confirmed last week, that arthritis drug Vioxx increased the risks of heart attacks and strokes.
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NEW YORK -- Merck &amp; Co.'s board said yesterday that a 20-month investigation funded by the pharmaceutical company found senior management acted responsibly in their development and marketing of the now withdrawn pain reliever Vioxx.
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Shares of Merck &amp; Co. plunged Monday after a news report suggested that the company knew about risks associated with its recently recalled Vioxx arthritis medication and tried to cover them up.
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&#151; Merck & Co., the US drug maker that recalled its Vioxx painkiller because of a link to heart disease, said short-term studies show the company's planned successor pill, Arcoxia, is safer.
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The arthritis drug Vioxx, used by 2  million people around the world, is being pulled off the market  after a study confirmed longstanding concerns that it raises  the risk of heart attack and stroke, the manufacturer, Merck &  Co. MRK.N, said on Thursday.
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Suspicions that the arthritis drug Vioxx could cause serious cardiovascular damage arose as early as 1999, the year Vioxx was approved by the Food and Drug Administration as a next-generation remedy that might be safer than older drugs like ibuprofen.