Studies on Painkillers in Jeopardy
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The spate of bad news about painkillers has dealt a major setback to what had been a highly promising effort to use the drugs to prevent a host of leading killers.
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Studies questioning the safety of the drugs Celebrex and Aleve have created a quandary for patients: If every drug that relieves their pain has worrisome side effects, what do they do?
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Painkillers suspected of causing fatal heart disease may act by starting the process of hardening the arteries, researchers proposed on Thursday.
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The withdrawal of Vioxx from the market in September and more recent concerns about its cousin Bextra have raised safety questions about this entire class of painkillers
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With Vioxx off the market because of links to heart problems and concerns growing about the related drugs Celebrex and Bextra, a pair of Food and Drug Administration advisory committees are assessing the safety of the popular painkillers.
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From coast to coast, warnings about several popular anti-inflammatory painkillers are triggering  confusion and anxiety.
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The Food and Drug Administration yesterday ordered a review of all prevention studies involving drugs such as Celebrex and Bextra, which have been associated with increased risk of heart problems. The agency also urged the public to limit use of over-the-counter pain medications.
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Similar painkilling drugs, including Celebrex, do not share the same risks, two new studies say.
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One of the first researchers to link the popular prescription painkillers Vioxx and Celebrex to heart problems blamed aggressive advertising for escalating public health risks and called for enabling the government to require better clinical trials to prevent future drug disasters.
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(December 29, 2004) - Six clinical studies at the University of Rochester Medical Center have ended because of findings that question the safety of the drugs under investigation.
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Scientists and European regulators are now questioning the safety of other pain relievers like Vioxx, saying they also might raise the risk of heart attack and stroke.
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Description: Pfizer says a study found an increased risk of heart problems with the painkiller Celebrex. The news comes after another painkiller, Vioxx, was withdrawn from the market.
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The troubles surrounding a major class of painkillers may ultimately help cure what has long ailed the US Food and Drug Administration.
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The safety of Celebrex and other pain relievers was questioned Wednesday as scientists in the United States and regulatory agencies in Europe said they feared such drugs might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.    One key researcher charged the U.S...
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Medicines used by millions of  Americans to relieve aches and pains will come under intense  scrutiny starting Wednesday as U.S. scientists scour dozens of  studies to determine if the drugs risk damaging the heart like  Merck & Co. Inc.'s MRK.N withdrawn arthritis pill Vioxx.
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The safety of common painkillers like ibuprofen is to be investigated, European regulators say.
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Description: Americans have recently learned that four popular painkillers -- Vioxx, Celebrex, Bextra and naproxen -- have been linked to an increased risk of heart attack and stroke.