HMO Reviews Vioxx, Study Sees Heart Risks
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Patients taking Merck & Co. Inc.'s Vioxx arthritis drug had a 50 percent greater chance of heart attacks and sudden cardiac death than individuals using Pfizer Inc.'s rival Celebrex medicine, according to a large study financed by the U.S. Food and Drug Administration.
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Two studies offer more evidence about  the dangers of some painkillers, adding kidney problems to  heart concerns already raised with the drug once sold as Vioxx,  researchers said on Tuesday.
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Merck &amp; Co., Inc., knew of problems with its blockbuster painkiller Vioxx long before the drug was pulled from the market in September due to newer studies that linked the medication to an increased risk of heart attack and stroke, the Wall Street Journal
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For years, evidence mounted that Vioxx might increase the risk of heart attacks or strokes. For years, its maker disputed such findings.
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TUESDAY, Dec. 5 (HealthDay News) -- U.S. Medicaid patients are less likely than patients with HMOs or private health insurance to receive recommended cardiac care, say researchers who analyzed data on more than 96,000 patients at 521 hospitals across the country.
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The U.S. Food and Drug Administration on Friday asked an outside group to review the way the agency monitors safety risks of medicines after they hit the market, such as Merck & Co. Inc.'s withdrawn painkiller Vioxx.
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Physicians and researchers estimate that Vioxx, a pain reliever found to increase cardiovascular risks, may have caused as many as 55,000 deaths in the United States.
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The U.S. drug safety officer who warned months ago about risks from Merck & Co. Inc.'s painkiller Vioxx won clearance to publish a study arguing the now-recalled drug may have caused up to 139,000 heart attacks and strokes, his attorney said on Monday.
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GAITHERSBURG, Md.  - The heart attack and stroke  risks linked to withdrawn arthritis drug Vioxx are an inherent  problem for similar pain pills, Vioxx maker Merck & Co. Inc.  told advisers to the U.S. Food and Drug Administration on  Wednesday.
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An analysis in a prominent medical journal reports that the painkiller Vioxx demonstrated an increased risk of heart attack four years ago and should have been withdrawn long before Sept.
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Merck & Co Inc. is evaluating why its withdrawn painkiller Vioxx raises the chance of heart attack and stroke, but it has not found a mechanism of action, a company official said on Monday.
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Top executives at pharmaceutical giant  Merck & Co. Inc. decided in May 2000 against developing a study  to test directly whether its Vioxx painkiller drug might pose a  heart risk, The New York Times reported on Saturday.
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Internal e-mails at US drug maker Merck show as long as four years ago the company saw a link between Vioxx and increased heart risk.
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Washington - The health risks found in pain-relieving drugs known as COX-2 inhibitors, such as Vioxx, underscore the need for health authorities to test drugs already on the market, a top United States (US) cardiologist has warned.
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The problems with Vioxx, taken off the market last week, raise questions about the Food and Drug Administration's safety review process. Observers say longer clinical trials should be required.
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In the first epidemiological study designed and executed specifically to determine the heart-attack risk associated with COX-2 inhibitors rofecoxib (Vioxx) and celecoxib (Celebrex), researchers at the University of Pennsylvania School of Medicine found a
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Top executives at pharmaceutical giant Merck & Co. Inc. decided in May 2000 against developing a study to test directly whether its Vioxx painkiller drug might pose a heart risk, The New York Times reported on Saturday.