FDA Study Finds Vioxx Increases Heart Attack Risk
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Patients taking Merck & Co.'s Vioxx arthritis drug had 50 percent more heart attacks and cases of sudden cardiac death than those taking Pfizer Inc.'s rival Celebrex drug, according to a large study financed by the U.S. Food and Drug Administration.
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Patients taking Merck & Co.'s Vioxx  arthritis drug had 50 percent more heart attacks and cases of  sudden cardiac death than those taking Pfizer Inc.'s rival  Celebrex drug, according to a large study financed by the U.S.  Food and Drug Administration.
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Vioxx, the painkiller recalled last September because of safety concerns, may have caused up to 140,000 cases of serious heart disease in the United States, researchers said on Tuesday.
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A U.S. Food and Drug Administration  preliminary analysis found a level of heart-attack risk with  GlaxoSmithKline Plc&#39;s  diabetes drug Avandia  similar to what was reported in a study earlier this week, the  agency confirmed on Friday.
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Two studies offer more evidence about   the dangers of some painkillers, adding kidney problems to   heart concerns already raised with the drug once sold as Vioxx,   researchers said on Tuesday.
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NEW YORK -- A new study has linked painkillers Vioxx, Celebrex, and Bextra to increased cardiovascular risk, reinforcing findings of other trials that have already sparked concern over the safety of a popular category of drugs.
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The risk of having a heart attack is elevated in the weeks after stopping use of nonsteroidal anti-inflammatory drugs, according to an article in the December issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.
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A study out Tuesday found that Vioxx users were nearly three times more likely to suffer a heart attack than people taking Celebrex, a similar pain reliever.
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The findings may be relevant to many people who take aspirin to prevent heart problems as well as a COX-2 inhibitor drug like Vioxx for arthritis.
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An independent study carried out at the University of Pennsylvania has shown that your risk of having a heart attack is three times greater with Vioxx than with Celebrex.
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Widely used anti-inflammatory drugs such as ibuprofen and naproxen could help reduce the risk of heart attacks, while abruptly halting the usage increases the risks, according to a large UK study.
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(CBS/AP) A study financed by the federal government has found that Vioxx, a popular anti-arthritis medicine, may cause serious heart problems, the Wall Street Journal reports.
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Merck &amp; Co.&#39;s Vioxx painkiller showed heart risk in studies four years before the drug was recalled, and it should have been pulled from the market then, according to a study published in the medical journal Lancet.
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Merck & Co Inc. is evaluating why  its withdrawn painkiller Vioxx raises the chance of heart  attack and stroke, but it has not found a mechanism of action,  a company official said on Monday.
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U.S. drug safety regulators are  coming under fire for their response to years of suspicions,  confirmed last week, that arthritis drug Vioxx increased the  risks of heart attacks and strokes.
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An analysis in a prominent medical journal reports that the painkiller Vioxx demonstrated an increased risk of heart attack four years ago and should have been withdrawn long before Sept.
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Dec 07  - Celebrex (celecoxib) does not raise the risk of heart attack to the extent that Vioxx (rofecoxib) does, according to an early online release from the Annals of Internal Medicine.