Pfizer Says Bextra, Heart Problems Linked
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Pfizer Inc. on Friday said two small  clinical trials showed heart bypass surgery patients taking  Bextra, an anti-inflammatory in the same class as the recently  withdrawn drug Vioxx, had a higher risk of stroke and heart  attack.
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It might not just be Vioxx that carries a risk of heart problems. Scientists and European regulators say users of similar pain-relief medications also may have cause for concern.
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Description: Scientists say the arthritis drug Bextra may pose increased risk of cardiovascular troubles. Bextra is related to Vioxx, which was pulled off the market in September for the same reason.
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Shares of Pfizer Inc. slipped on Wednesday, following reports that a study had likened the companyâs Bextra arthritis drug to Merck&#39;s Vioxx in terms of its cardiovascular risks.
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Willie Henry started taking Bextra four years ago for a painful ruptured disc. He says all of a sudden he couldn&#39;t stop itching, his blood pressure skyrocketed, his heart started fluttering and he couldn&#39;t wake up on his own.
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Doctors writing in a prominent medical  journal on Friday recommended that physicians stop prescribing  Pfizer Inc.'s Bextra painkiller, just as a large study found  the drug maker's sister drug, Celebrex, doubled risk of heart  attacks.
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The US Food and Drug Administration yesterday ordered strengthened boxed labels for Pfizer&#39;s Bextra, warning of possible heart and blood clotting problems.
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The controversy over painkillers known as Cox-2 inhibitors like Vioxx, Celebrex and Bextra and major cardiovascular events has prompted a leading heart specialist to speak out.
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More evidence of how painkillers  called COX-2 inhibitors can raise the risk of heart disease was  published Monday, showing Pfizer Inc.'s Bextra can triple the  risk of heart attack and stroke in certain patients.
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U.S. health officials Thursday called on doctors to limit prescribing Pfizer Inc. painkillers Celebrex and Bextra in light of recent evidence that they may increase the risk of heart attack and stroke.
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The spotlight is likely to be on Pfizer on Wednesday when federal drug regulators begin hearings on cox-2 drugs, the medicines that include Celebrex and Bextra.
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WASHINGTON (CBS.MW) -- The US Food and Drug Administration said on Thursday that Pfizer&#39;s new pain drug Bextra will carry a labeled warning about a risk of cardiac and blood-clotting problems.
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Less than a week after two sets of new data raised questions about the cardiovascular safety of two widely used painkillers, the Pfizer Inc.
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U.S. health officials on Thursday  called on doctors to limit prescribing Pfizer Inc. painkillers  Celebrex and Bextra in light of recent evidence that they may  increase the risk of heart attack and stroke.
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NEW YORK, OCTOBER 15 : PFIZER Inc. on Friday said two clinical trials showed patients taking its anti-inflammatory drug Bextra, had a higher risk of cardio-vascular events during high-risk coronary bypass surgery.
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The U.S. Food and Drug  Administration on Thursday ordered the review of preventative  studies involving Pfizer Inc.'s painkillers Celebrex and  Bextra, in light of recent evidence they may increase the risk  of heart attack and stroke.
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NEW YORK - Pfizer Inc. said it found an increased risk of heart attacks for patients taking high dosages of its top-selling painkiller Celebrex, the same problem that led to the withdrawal of its one-time competitor Vioxx.