New Study Links Pfizer's Bextra, Similar to Vioxx, to Heart Attacks
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Patients given PfizerÂs painkiller Bextra have more than twice as many heart attacks and strokes as those given placebos, according to preliminary results of a study.
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Nov. 10, 2004 (New Orleans) -- A leading heart researcher says the painkiller Bextra increases the risk of heart attacks and strokes and may pose a greater risk than Vioxx.
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WASHINGTON -- A study led by a Food and Drug Administration safety official projects that the widespread use of Vioxx may have led to more than 27,000 heart attacks and sudden cardiac deaths before the drug&#39;s abrupt withdrawal last week by Merck &amp; Co.
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Pfizer Inc.'s painkiller Bextra will  come with a new warning about the possibility of heart attacks  and blood clots in patients who have just had heart bypass  surgery, the U.S. Food and Drug Administration said on  Thursday.
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The Food and Drug Administration yesterday ordered a review of all prevention studies involving drugs such as Celebrex and Bextra, which have been associated with increased risk of heart problems. The agency also urged the public to limit use of over-the-counter pain medications.
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Doctors writing in a prominent medical  journal on Friday recommended that physicians stop prescribing  Pfizer Inc.'s Bextra painkiller, just as a large study found  the drug maker's sister drug, Celebrex, doubled risk of heart  attacks.
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Patients taking Merck & Co.'s Vioxx  arthritis drug had 50 percent more heart attacks and cases of  sudden cardiac death than those taking Pfizer Inc.'s rival  Celebrex drug, according to a large study financed by the U.S.  Food and Drug Administration.
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People who take Merck & Co. Inc.'s analgesic Vioxx are nearly three times as likely to have heart attacks as those taking Pfizer Inc.'s Celebrex, according to an independent study published on Monday.
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A clinical trial for Novartis AG's  experimental painkiller Prexige showed the risk of heart  attack, stroke and death was "similar" to Merck & Co. Inc.'s  now withdrawn Vioxx, U.S. regulatory staff said in documents  released on Friday.
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Pfizer Inc. on Monday said a major new trial will test whether its popular Celebrex arthritis drug increases the risk of heart attacks, as seen with Merck and Co.
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Two studies offer more evidence about  the dangers of some painkillers, adding kidney problems to  heart concerns already raised with the drug once sold as Vioxx,  researchers said on Tuesday.
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FRIDAY, Dec. 17 (HealthDayNews) -- Pfizer Inc. said Friday that a study of its popular pain drug Celebrex in cancer patients had found an apparent increased risk of heart attack and other cardiovascular problems.
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After Vioxx was taken off pharmacy shelves two months ago because a study showed the popular painkiller doubled the risk of heart attacks and strokes, Janet Whichard switched to Bextra to relieve her arthritis pain.
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Two studies offer more evidence about   the dangers of some painkillers, adding kidney problems to   heart concerns already raised with the drug once sold as Vioxx,   researchers said on Tuesday.
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Study confirmed concerns that the drug significantly raises the risk of heart attack and stroke.
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The US Food and Drug Administration on Thursday ordered the review of preventative studies involving Pfizer Inc.&#39;s painkillers Celebrex and Bextra, in light of recent evidence they may increase the risk of heart attack and stroke.
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It might not just be Vioxx that carries a risk of heart problems. Scientists and European regulators say users of similar pain-relief medications also may have cause for concern.