Cardiovascular Risk with Celecoxib (Celebrex), UK Agency Informs
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We have today been informed of new clinical trial data for celecoxib (Celebrex), showing an increased risk of heart attack, stroke and death (relative to placebo).
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Widely used anti-inflammatory drugs such as ibuprofen and naproxen could help reduce the risk of heart attacks, while abruptly halting the usage increases the risks, according to a large UK study.
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Description: Pfizer says a study found an increased risk of heart problems with the painkiller Celebrex. The news comes after another painkiller, Vioxx, was withdrawn from the market.
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Washington - The health risks found in pain-relieving drugs known as COX-2 inhibitors, such as Vioxx, underscore the need for health authorities to test drugs already on the market, a top United States (US) cardiologist has warned.
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BLOW TO ANOTHER DRUG: A cancer prevention study found people taking very high doses of the painkiller Celebrex had higher risk of heart problems.
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Celebrex, the nation&#39;s leading painkiller, raises the risk of heart attack when taken at very high doses, the drug&#39;s maker said Friday in the latest blow to a class of powerful and widely touted drugs.
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The US Food and Drug Administration on Thursday ordered the review of preventative studies involving Pfizer Inc.&#39;s painkillers Celebrex and Bextra, in light of recent evidence they may increase the risk of heart attack and stroke.
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THE Ministry of Health yesterday advised persons currently using Celebrex and any other drug in its class to consult with their physicians with any concerns, following reports of cardiovascular side effects associated with the use of the drug.
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Concern over the safety of anti-inflammatory drugs such as Pfizer&#39;s Celebrex intensified on Tuesday after regulators advised 600,000 Britons with heart problems to switch to other treatments as soon as convenient.
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WASHINGTON -- Preliminary results of a new study suggest that high doses of Celebrex, a popular arthritis drug, can dramatically increase a person&#39;s risk of heart attack.
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Doctors are being urged to think twice before prescribing certain painkillers in light of new evidence suggesting they may increase cardiovascular risk.
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Swiss drugmaker Novartis AG has informed doctors in Europe of new restrictions on prescribing lumiracoxib, its COX-2 inhibitor sold under the trade name Prexige, including regular liver monitoring, Britain's drug regulator said.
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NEW YORK  - A new study adds to the  evidence that cardiac risk is increased in Vioxx (rofecoxib)  users, even in those without a history of heart attack. The  results also show that at lower doses of Vioxx, concurrent  aspirin use can reduce the risk and the risk decreases to  normal levels after Vioxx is discontinued.
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The Food and Drug Administration on Thursday ordered a review of all prevention studies involving drugs such as Celebrex and Bextra, which have been associated with increased risk of heart problems. The agency also urged the public to limit use of over-the-counter pain medications.
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NEW YORK - A new round of trials have shown a boosted risk of heart problems among patients taking the painkiller Celebrex, manufacturer Pfizer Inc.
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Two leading heart experts called for urgent investigations on Wednesday into whether all painkilling drugs known as COX-2 inhibitors may raise the risk of heart attack in some people.
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NEW YORK -- A new study has linked painkillers Vioxx, Celebrex, and Bextra to increased cardiovascular risk, reinforcing findings of other trials that have already sparked concern over the safety of a popular category of drugs.