Coxibs have different cardiovascular risk profiles
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Risks of first, nonfatal myocardial infarction was tripled with rofecoxib, compared with celecoxib users, Annals study shows. To determine whether and to what extent COX-2-selective inhibitors affected individuals
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NEW YORK  - A new study adds to the  evidence that cardiac risk is increased in Vioxx (rofecoxib)  users, even in those without a history of heart attack. The  results also show that at lower doses of Vioxx, concurrent  aspirin use can reduce the risk and the risk decreases to  normal levels after Vioxx is discontinued.
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Concern over the recently publicized risks of drugs such as Vioxx and Celebrex has left doctors and patients with difficult choices.
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Celebrex, an arthritis drug in the same class as the recalled painkiller Vioxx, caused irregular heartbeats in fruit flies and in heart cells taken from laboratory rats, U.S. researchers said on Friday.
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NEW YORK  - In rheumatoid arthritic patients, some traditional risk factors impart a greater risk of developing cardiovascular disease, while others confer a lower risk, compared with those without rheumatoid arthritis, according to a report in the Annals of the Rheumatic Diseases.
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More evidence of how painkillers  called COX-2 inhibitors can raise the risk of heart disease was  published Monday, showing Pfizer Inc.'s Bextra can triple the  risk of heart attack and stroke in certain patients.
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Arthritis drugs known as COX-2  inhibitors raise blood pressure more than older pain relievers,  which may explain why the newer medicines have been linked to  heart attacks, Australian researchers reported on Monday.
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By Amanda Gardner, HealthDay Reporter    HealthDayNews -- A new painkiller, one of the family of COX-2 inhibitors, appears to be as safe as certain other drugs when it comes to cardiac effects.    And it's safer than other drugs that can cause gastrointestinal complications, new research contends...
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New research suggests that top-selling pain reliever Celebrex does not carry the same heart attack risk as Vioxx, a similar drug pulled from the market in September because of safety concerns.
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Compared with ibuprofen, the use of the lumiracoxib by patients with osteoarthritis is associated with a lower risk of gastric ulcers. The risk is similar to that seen with celecoxib (Celebrex), another COX-2 inhibitor.
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Pain relievers in the same class as  Vioxx may not carry the same cardiovascular risk as the  blockbuster drug that was withdrawn from the market three weeks  ago, a U.S. regulator said on Wednesday.
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A new study finds that Celebrex, a painkiller from the family of cox-2-inhibitors, is safer than Vioxx, when it comes to the risk for heart attack.
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Doctors are struggling to decide which pain relievers to prescribe now that they know that drugs like Vioxx and Celebrex pose serious heart risks.
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THE FEAR: Both Vioxx and Celebrex are known as cox-2 inhibitors. Some scientists have been warning that all cox-2 inhibitors have the same dangers as Vioxx.
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Pfizer Inc. said it has found an increased risk of heart attacks with patients taking its top-selling painkiller Celebrex, a drug that is in the same class as Vioxx, but has no plans to remove it from the market.
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BOSTON - The safety of Celebrex and other pain relievers was questioned Wednesday as scientists in the United States and regulatory agencies in Europe said they feared such drugs might raise the same risk of heart problems as those blamed on the arthritis
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People who take Merck & Co. Inc.'s  analgesic Vioxx are nearly three times as likely to have heart  attacks as those taking Pfizer Inc.'s Celebrex, according to an  independent study published on Monday.