Pfizer, Merck Argue Over Painkiller Risks
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GAITHERSBURG, Md.  - Rival drug giants Pfizer Inc.  PFE.N and Merck & Co. Inc. MRK.N argued conflicting views  of the dangers of their pain relievers on Wednesday to U.S.  science advisers weighing the risks of medicines similar to  recalled arthritis drug Vioxx.
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Pfizer Inc. said it found an increased risk of heart attacks and strokes for patients taking high dosages of its top-selling arthritis painkiller Celebrex -- the same problem that led to the withdrawal of its one-time competitor, Vioxx.
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Millions of patients and billions of dollars in sales could be affected by knowing whether the risks to the heart posed by Merck's Vioxx extend to other COX-2 inhibitors.
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Oct. 6, 2004 - Scientists in the United States and regulatory agencies in Europe on Wednesdsay questioned whether Celebrex and other pain relievers might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.
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Drug giant Pfizer Inc. reiterated Thursday that its arthritis drug Celebrex was safe to use after competitor Merck &amp; Co. pulled its arthritis drug Vioxx off the market worldwide after studies showed it raised the risk of heart attack.
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The safety of Celebrex and other pain relievers was questioned Wednesday as scientists in the United States and regulatory agencies in Europe said they feared such drugs might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.    One key researcher charged the U.S...
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NEW YORK (Dow Jones/AP) -- Pfizer Inc. defended the safety of its painkiller Celebrex on Thursday after a newspaper reported that documents from Canadian health authorities linked the drug to the deaths of
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People who take Merck & Co. Inc.'s  analgesic Vioxx are nearly three times as likely to have heart  attacks as those taking Pfizer Inc.'s Celebrex, according to an  independent study published on Monday.
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Pfizer Inc. will warn doctors that its Bextra painkiller, in the same group of drugs as Merck &amp; Co.&#39;s withdrawn Vioxx, is linked to an elevated risk of blood clots, heart attacks and strokes in cardiac-surgery patients.
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It might not just be Vioxx that carries a risk of heart problems. Scientists and European regulators say users of similar pain-relief medications also may have cause for concern.
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U.S. health regulators recommended  on Thursday that doctors limit prescribing painkillers like  Pfizer Inc.'s Celebrex and Bextra, in light of recent evidence  that they may increase the risk of heart attack and stroke.
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NEW YORK - Since Merck&#39;s Vioxx was pulled from the market for increasing the risk of heart attack and stroke in a long-term study, there has been heated debate over whether other, similar medicines, such as Pfizer&#39;s Celebrex and Bextra, carry similar risks
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ATLANTIC CITY, New Jersey  - Merck & Co.  failed to provide adequate warnings about health risks tied to its withdrawn arthritis drug Vioxx in one case, but gave adequate warning in another, a New Jersey jury found on Friday in a split decision in two suits tried simultaneously.
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Merck & Co Inc. is evaluating why its withdrawn painkiller Vioxx raises the chance of heart attack and stroke, but it has not found a mechanism of action, a company official said on Monday.
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A study in a leading medical journal found Pfizer&#39;s Celebrex does not pose the same risk of causing heart attacks as Vioxx, the competing medicine Merck withdrew from the market because of safety concerns.
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Patients taking Merck & Co.'s Vioxx  arthritis drug had 50 percent more heart attacks and cases of  sudden cardiac death than those taking Pfizer Inc.'s rival  Celebrex drug, according to a large study financed by the U.S.  Food and Drug Administration.
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At a research and development meeting for analysts on Nov. 30, Pfizer (PFE ) stayed on message all day long. Despite questions about possible safety issues with arthritis pain medication Celebrex, patent challenges