Europe Orders Full Safety Probe of Cox-2 Drugs
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The European Commission has ordered a full-scale probe into the safety of five remaining Cox-2 arthritis drugs, following last month&#39;s
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US health regulators recommended on Thursday that doctors limit prescribing painkillers like Pfizer Inc.&#39;s Celebrex and Bextra, in light of recent evidence that they may increase the risk of heart attack and stroke.
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Nov. 5, 2004 -- FDA officials announced Friday that they will launch a review of the agency&#39;s drug monitoring policies in the wake of recent high-profile safety concerns about widely used drugs, including antidepressants and Vioxx.
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European regulators are carrying out a safety review following fears that five arthritis drugs could increase the risk of strokes and heart attacks.
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WEDNESDAY, Aug. 30 (HealthDay News) -- The final word on whether the cox-2 painkiller Celebrex might be used to prevent colon cancer is a definite &quot;no,&quot; according to the long-awaited results of two major studies.
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Merck &amp; Co., which withdrew the Vioxx painkiller last month because of a heart risk, said yesterday that US regulators have asked for more safety data before they will approve the medicine&#39;s successor, Arcoxia.
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Far-reaching safety rules on tens of thousands of chemicals used in everyday items from car seats to face cream took effect in the European Union on Friday, obliging firms to show their products comply.
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The safety of Celebrex and other pain relievers was questioned Wednesday as scientists in the United States and regulatory agencies in Europe said they feared such drugs might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.
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Two leading heart experts called for urgent investigations on Wednesday into whether all painkilling drugs known as COX-2 inhibitors may raise the risk of heart attack in some people.
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The story of COX-2 drugs is an example of how difficult it is for the F.D.A. to monitor the safety of drugs after they have been approved for the market.
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Scientists and European regulators are now questioning the safety of other pain relievers like Vioxx, saying they also might raise the risk of heart attack and stroke.
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Two leading heart experts called for  urgent investigations on Wednesday into whether all painkilling  drugs known as COX-2 inhibitors may raise the risk of heart  attack in some people.
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The controversy over painkillers known as Cox-2 inhibitors like Vioxx, Celebrex and Bextra and major cardiovascular events has prompted a leading heart specialist to speak out.
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The safety of common painkillers like ibuprofen is to be investigated, European regulators say.
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Two studies released yesterday have turned up new evidence that all of the popular arthritis painkillers known as cox-2 inhibitors may put users at greater risk of heart attacks and strokes.
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FRIDAY, Oct. 8 (HealthDayNews) -- A week after drug giant Merck & Co. withdrew its arthritis drug Vioxx from the market, doubts are being raised about the safety of the two other approved medications in this class, Bextra and Celebrex.
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In the first epidemiological study designed and executed specifically to determine the heart-attack risk associated with COX-2 inhibitors rofecoxib (Vioxx) and celecoxib (Celebrex), researchers at the University of Pennsylvania School of Medicine found a