Studies on Painkillers In Jeopardy
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The spate of bad news about painkillers has dealt a major setback to what had been a highly promising effort to use the drugs to prevent a host of leading killers, including many types of cancer, Alzheimer&#39;s and other forms of dementia.
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By Tampone, Kevin  CICERO - Cancer research is daunting for a variety of reasons, not the least of which is the massive number of substances that might be effective in future drugs.
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Medicines used by millions of  Americans to relieve aches and pains will come under intense  scrutiny starting Wednesday as U.S. scientists scour dozens of  studies to determine if the drugs risk damaging the heart like  Merck & Co. Inc.'s MRK.N withdrawn arthritis pill Vioxx.
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The Food and Drug Administration yesterday called for an evaluation of all prevention studies involving two controversial painkillers - Celebrex and Bextra - to ensure adequate protection for participants who use the pills.
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The safety of common painkillers like ibuprofen is to be investigated, European regulators say.
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Doctors are being urged to think twice before prescribing certain painkillers in light of new evidence suggesting they may increase cardiovascular risk.
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Recent reports of popular pain-relievers - Vioxx, Celebrex and Aleve - increasing the risk of heart attacks and strokes have the nation in a panic.
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Merck &amp; Co.&#39;s Vioxx painkiller showed heart risk in studies four years before the drug was recalled, and it should have been pulled from the market then, according to a study published in the medical journal Lancet.
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WASHINGTON - The spate of bad news about painkillers has dealt a major setback to what had been a highly promising effort to use the drugs to prevent a host of leading killers, including many types of cancer, Alzheimer&#39;s and other forms of dementia.
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Scientists in the United States and regulatory agencies in Europe on Wednesdsay questioned whether Celebrex and other pain relievers might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.
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One of the first researchers to link the popular prescription painkillers Vioxx and Celebrex to heart problems blamed aggressive advertising for escalating public health risks and called for enabling the government to require better clinical trials to prevent future drug disasters.
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A study testing whether naproxen would reduce the risk of Alzheimer's disease was halted after researchers noted an increase in heart attack and stroke among participants who were taking the pain reliever.
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With Vioxx off the market because of links to heart problems and concerns growing about the related drugs Celebrex and Bextra, a pair of Food and Drug Administration advisory committees are assessing the safety of the popular painkillers.
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Doctors are struggling to decide which pain relievers to prescribe now that they know that drugs like Vioxx and Celebrex pose serious heart risks.
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Without clearer evidence of the safety of painkillers similar to Vioxx, doctors should avoid prescribing them for patients at risk of heart disease, according
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Science & environment: Warning by scientists after study reveals toll from accidents, drugs and alcohol.
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A day after troubling reports about the popular pain relief drug Celebrex, more questions are being asked about the approval process for such drugs.