Actos, Avandia heart failure risks confirmed: study
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The diabetes drugs Actos and Avandia raise the risk of heart failure but do not increase the risk of heart-related death, U.S. researchers said on Thursday, confirming earlier findings.
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Recent studies have suggested that Celebrex and Bextra may increase the risk of heart attack and stroke.
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The potential heart risks of GlaxoSmithKline Plc's diabetes drug Avandia are still not clear, the head of the U.S. Food and Drug Administration told lawmakers who questioned the agency's oversight of the widely used pill on Wednesday.
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A U.S. Food and Drug Administration preliminary analysis found a level of heart-attack risk with GlaxoSmithKline Plc'sdiabetes drug Avandia similar to what was reported in a study earlier this week, the agency confirmed on Friday.
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-- In the month after a surprising analysis revealed possible heart risks from the blockbuster diabetes drug Avandia, reports of side effects to federal regulators tripled.
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The government's own preliminary evaluation of the diabetes pill Avandia confirms the heart risks reported in a study earlier this week and suggests that as many as 60,000 to 100,000 heart attacks might be linked to its use since it came on the market eight years ago, a leading member of Congress said Thursday.
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The risk of having a heart attack is elevated in the weeks after stopping use of nonsteroidal anti-inflammatory drugs, according to an article in the December issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.
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The move follows recent studies suggesting that the medications might cause heart attacks or make cancer worse in some patients.
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GlaxoSmithKline's diabetes drug Avandia was not to blame for heart deaths in a trial to see if treating diabetes would reduce heart disease, U.S. government-funded researchers said on Wednesday.
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The Food and Drug Administration on Thursday ordered a review of all prevention studies involving drugs such as Celebrex and Bextra, which have been associated with increased risk of heart problems. The agency also urged the public to limit use of over-the-counter pain medications.
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WASHINGTON - GlaxoSmithKline PLC's Avandia, the world's best-selling diabetes drug last year, will carry US regulators' strongest warning on the risk of heart attacks.
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NEW YORK  - In people with diabetes and  heart failure, treatment with the beta-blocker metoprolol CR/XL  (controlled release/extended release) safely reduces the risk  of hospitalization and death, research shows.
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The anti-impotence drug could be a good treatment for heart failure, US researchers believe.
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NEW YORK  - People with heart disease who don't take their medications as prescribed risk suffering a heart attack or other heart-related event, a new study shows.
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NEW YORK  - Patients with diabetes, especially women, who take thiazolidinediones, which include commonly prescribed drugs such as Avandia and Actos, may have an increased risk of developing cancer, according to a new report.
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People with heart disease who  don&#39;t take their medications as prescribed risk suffering a  heart attack or other heart-related event, a new study shows.
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The widely used diabetes pill Actos appears to lower a patient's chances of death, heart attack or stroke, unlike its beleaguered chief rival Avandia, a new analysis shows. However, it also carries an increased risk of nonfatal heart failure, the analysis showed, confirming earlier studies.