Clinical Trials: Are Drugmakers' Studies Biased?
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A new analysis finds that clinical trials of breast-cancer treatments by drugmakers show positive results far more often than non-industry trials. Why the difference?
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An early analysis from an ongoing study of GlaxoSmithKline Plc's Avandia was unable to show whether there was any increase in heart attacks among patients, but several experts said the evidence still suggested the popular diabetes drug raised the risk of heart attack.
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The Food and Drug Administration does very little to ensure the safety of the millions of people who participate in clinical trials, a federal investigator has found.
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In a recent trial, a pain medication wasn't as effective as had been hoped.
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BusinessWeek Online - The news last week that GlaxoSmithKline&#39;s  popular diabetes drug Avandia may increase the risk of heart attacks is now causing a rift among doctors by specialty, leading to charges by each side that the other is endangering patients. Endocrinologists, who treat diabetics, tend to regard the data, which was published in The New England Journal of Medicine, with skepticism, pointing to weaknesses in the study, particularly when compared to more rigorous clinical trials. Cardiologists and drug safety experts, foremost among them study author Dr. ...
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An interview with development-stage drugmaker Pharmacopeia.
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TUESDAY, June 20 (HealthDay News) -- Doctors who participated in a drug company-sponsored trial of asthma medications were more likely to prescribe that company's drugs.
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Patient deaths from experimental cancer drugs during initial human studies declined dramatically from 1991 to 2002, suggesting that better oversight and less-toxic
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A panel of experts reaches mixed conclusions on the safety and effectiveness of drug-coated stents.
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Some of the health benefits claimed for a new weight loss drug may not be justified, say experts.
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Transplants of insulin-making cells have not lived up to the promise they showed in an initial trial.
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The world's leading drug companies have promised to publish more data about clinical trials into new medicines to reassure the public about their safety.
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(HealthDayNews) -- Here are the latest clinical trials, courtesy of CenterWatch:
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Patients who took a Sanofi-Aventis SA obesity drug in clinical trials were more likely to report suicidal thoughts or actions than others who got a placebo, U.S. drug reviewers said in an analysis released on Monday.
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Some pharma industry players decide to integrate crowdsourcing into R&amp;D to help reduce the high costs of developing new medicines. Assignment Zero interviews Dr. Alpheus Bingham of Innocentive for insights into how it works.
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Drug makers are exploring the possibility of tying pharmaceutical prices to performance.
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The maker of the controversial diabetes pill Avandia pointed to early results of its own study Tuesday, saying they offered reassuring evidence the drug doesn't raise heart risks. However, outside experts called the results inconclusive at best and a sign of greater risk at worst.