Experts Raise Questions About Vioxx Decision
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Two leading heart experts called for urgent investigations on Wednesday into whether all painkilling drugs known as COX-2 inhibitors may raise the risk of heart attack in some people.
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Makers of the arthritis drug Vioxx and the FDA are the subject of Senate scrutiny today...and an Iowa Senator is asking the tough questions.
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Amid questions about whether the arthritis drug Vioxx was taken off the market soon enough, a key senator suggested Friday that an independent board of drug safety might be needed to ensure the safety of medications after they're approved for the market.
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Merck & Co Inc. is evaluating why its withdrawn painkiller Vioxx raises the chance of heart attack and stroke, but it has not found a mechanism of action, a company official said on Monday.
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Soon after the anti-arthritis and painkiller drug Vioxx was approved by the Food and Drug Administration in 1999, credible questions surfaced about the risk of serious cardiovascular problems in people who took it.
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Merck (MRK) officials on Wednesday called a press conference to reiterate that they did not believe until last month that Vioxx raised users&#39; risk of heart attacks or strokes.
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For years, evidence mounted that Vioxx might increase the risk of heart attacks or strokes. For years, its maker disputed such findings.
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Patients who were switched from the prescription pain reliever Vioxx, taken off the market in September, to Celebrex or Aleve want to know what they should do now that the safety of both alternatives is being questioned.
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Congress has been investigating the FDA&#39;s decisions in both the Vioxx and antidepressant cases. The probes have focused on agency reviewers who warned about potential problems but claimed their research was ignored or suppressed by other officials.
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Patients taking Vioxx for pain relief have many alternatives, and the popular drug&#39;s withdrawal from worldwide markets yesterday should have little practical effect on clinical care, experts said.
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An Oregon man stopped taking the painkiller Vioxx when it was pulled from the market, switching to Bextra. Then questions were raised about Bextra &#151; and four other drugs &#151; and he returned to his doctor with a new set of worries. Similar conversations are happening between doctors and patients all around the country.
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Description: A voluntary withdrawal of Vioxx from the market is the latest in a string of safety issues for the drug market. Dr. Alistair Wood, of the Vanderbilt School of Medicine, says the serious dangers
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When Merck&#39;s arthritis drug Vioxx was withdrawn from the market in September, concerns over drug safety were pretty much under the radar for the most part, but not today.
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A panel of experts reaches mixed conclusions on the safety and effectiveness of drug-coated stents.
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Merck&#39;s (MRK :NYSE - news - research) decision to withdraw its popular arthritis drug Vioxx from the market in late September has raised questions about the process leading up to its regulatory approval in 1999 as well as the importance of subsequent
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The safety of Celebrex and other pain relievers was questioned Wednesday as scientists in the United States and regulatory agencies in Europe said they feared such drugs might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.    One key researcher charged the U.S...
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Is the US Food &amp; Drug Administration failing? That was the testimony of one senior FDA official last week concerning Merck&#39;s withdrawal of the Vioxx anti-pain drug.