Vioxx Study Suggests Heart Risks; Kaiser to Review
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Patients taking Merck & Co. Inc.'s Vioxx arthritis drug had a 50 percent greater chance of heart attacks and sudden cardiac death than individuals using Pfizer Inc.'s rival Celebrex medicine, according to a large study financed by the U.S. Food and Drug Administration.
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An independent study carried out at the University of Pennsylvania has shown that your risk of having a heart attack is three times greater with Vioxx than with Celebrex.
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Merck &amp; Co Inc. is evaluating why its withdrawn painkiller Vioxx raises the chance of heart attack and stroke, but it has not found a mechanism of action, a company official said on Monday.
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Celebrex, an arthritis drug in the same class as the recalled painkiller Vioxx, caused irregular heartbeats in fruit flies and in heart cells taken from laboratory rats, U.S. researchers said on Friday.
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Medicines used by millions of Americans to relieve aches and pains will come under intense scrutiny starting Wednesday as U.S. scientists scour dozens of studies to determine if the drugs risk damaging the heart like Merck & Co. Inc.'s withdrawn arthritis pill Vioxx.
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Pfizer Inc. on Monday said a major new  trial will test whether its  popular Celebrex arthritis drug  increases the risk of heart attacks, as seen with Merck and  Co.'s recalled Vioxx pill.
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Vioxx, the painkiller recalled last September because of safety concerns, may have caused up to 140,000 cases of serious heart disease in the United States, researchers said on Tuesday.
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People who take Merck & Co. Inc.'s analgesic Vioxx are nearly three times as likely to have heart attacks as those taking Pfizer Inc.'s Celebrex, according to an independent study published on Monday.
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WASHINGTON -- The nation&#39;s largest health management organization is considering changing how it prescribes Vioxx after a government study showed that high doses of the arthritis drug tripled patients&#39; risk of heart attacks and sudden cardiac death.
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Less than six weeks after Vioxx was pulled from pharmacy shelves because of evidence it increased a patient&#39;s risk of heart attack or stroke, some researchers are raising
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A study in a leading medical journal found Pfizer&#39;s Celebrex does not pose the same risk of causing heart attacks as Vioxx, the competing medicine Merck withdrew from the market because of safety concerns.
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a widely prescribed arthritis treatment - more than doubled patients&#39; risk of heart problems in a clinical study. The announcement, 11 weeks after Merck &amp; Co.
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NEW YORK - In the wake of Merck&#39;s Vioxx debacle, doctors are scrambling to understand why the drug doubled the risk of heart attacks and strokes--and how to know if other medicines carry similar risks.
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Merck & Co. faces a dual threat from health insurers and patients' lawyers, after a U.S. study suggested its Vioxx arthritis drug carries a greater risk than rival medicines.
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Millions of patients and billions of dollars in sales could be affected by knowing whether the risks to the heart posed by Merck's Vioxx extend to other COX-2 inhibitors.
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Pfizer Inc. said on Monday it plans to sponsor a major clinical study to further assess the cardiovascular safety of its arthritis drug Celebrex following the withdrawal of Merck & Co.'s Vioxx, a drug in the same class.
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Merck &amp; Co.&#39;s Vioxx painkiller&#39;s heart risk was evident in studies four years before the drug was recalled -- and it should have been pulled from the market then, according to a study published in the medical journal Lancet.