Doctors Donât Agree on Bextra Risk
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Less than six weeks after Vioxx was pulled from pharmacy shelves because of evidence it increased a patient&#39;s risk of heart attack or stroke, some researchers are raising
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Pfizer Inc. will warn doctors that its Bextra painkiller, which is in the same group of drugs as Merck &amp; Co.&#39;s withdrawn Vioxx, is linked to an elevated risk of blood clots, heart attacks and strokes in cardiac-surgery patients.
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Drugmaker Pfizer Inc. is in talks with  regulators over a likely change to arthritis drug Bextra's  label to carry the strictest possible warning alerting doctors  of the risk of a potentially deadly skin reaction, the company  said in a regulatory filing.
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A study suggesting arthritis drug Bextra doubles patients&#39; heart attack and stroke risks drew a sharp rebuttal Wednesday from the drug&#39;s maker, Pfizer (PFE), as its stock price dipped.
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Many doctors refuse to admit that simple chance is a factor in how well some of their patients do.
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The government is warning of potential heart problems associated with the use of the painkiller Bextra in people who have recently had heart bypass surgery.
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Oct. 15, 2004 -- Bextra -- one of two US approved Vioxx sister drugs -- may cause rare skin and heart side effects, its manufacturer today warned doctors.
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Doctors writing in a prominent medical journal on Friday recommended that physicians stop prescribing Pfizer Inc.'s Bextra painkiller, just as a large study found the drugmaker's sister drug, Celebrex,  doubled risk of heart attacks.
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WASHINGTON -- The Food and Drug Administration is preventing an agency scientist from presenting the largest, most up-to-date study of popular painkillers like Bextra, Celebrex and Vioxx during an FDA meeting next week on heart risks posed by the drugs, a US senator charged.
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Pfizer Inc. will warn doctors that its Bextra painkiller, in the same group of drugs as Merck &amp; Co.&#39;s withdrawn Vioxx, is linked to an elevated risk of blood clots, heart attacks and strokes in cardiac-surgery patients.
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Patients taking a common drug to prevent blood clots to reduce heart attack and stroke risk now rely on a doctor's determination that they will not suffer excessive bleeding.
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Pfizer Inc. on Friday said two small  clinical trials showed heart bypass surgery patients taking  Bextra, an anti-inflammatory in the same class as the recently  withdrawn drug Vioxx, had a higher risk of stroke and heart  attack.
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Pfizer Inc. on Friday said two clinical trials showed patients taking its anti-inflammatory drug Bextra had a higher risk of cardiovascular events during high-risk coronary bypass surgery.
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Drugmaker Pfizer Inc. is in talks with  regulators over a likely change to arthritis drug Bextra's  label to warn doctors about the risk of a potentially deadly  skin reaction, the company said in a regulatory filing.
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NEW YORK -- A new study has linked painkillers Vioxx, Celebrex, and Bextra to increased cardiovascular risk, reinforcing findings of other trials that have already sparked concern over the safety of a popular category of drugs.
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Bulging costs keep the drugmaker from showing a profit.
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The Food and Drug Administration has published a note on its Web site regarding new warnings added to the labeling for Bextra, an arthritis pain drug made by Pfizer (nyse: PFE - news - people ). The warnings