Diabetes Drug Still Has Heart Risks, Doctors Warn
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A study intended to demonstrate the safety of a diabetes treatment seems, instead, to have added to the controversy.
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The move follows recent studies suggesting that the medications might cause heart attacks.
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The widely used diabetes pill Actos appears to lower a patient's chances of death, heart attack or stroke, unlike its beleaguered chief rival Avandia, a new analysis shows. However, it also carries an increased risk of nonfatal heart failure, the analysis showed, confirming earlier studies.
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Daily aspirin is usually recommended for people at increased risk for heart disease, and people with diabetes come into that category. While the proportion of diabetic patients who take aspirin has increased in recent years in the US, new research indicates that some are still not doing so.
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Millions of adults at high risk of diabetes could ward off the disease by taking a drug commonly used to treat it, according to the largest diabetes prevention study yet conducted.
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All studies to date provide inconsistent data about the potential contribution of GlaxoSmithKline Plc's diabetes drug Avandia to heart attack risk, the head of the Food and Drug Administration said in testimony prepared for a congressional hearing on Wednesday.
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All studies so far provide inconsistent results about the potential heart risks of GlaxoSmithKline Plc's diabetes drug Avandia, the head of the U.S. Food and Drug Administration told lawmakers on Wednesday.
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A U.S. Food and Drug Administration  preliminary analysis found a level of heart-attack risk with  GlaxoSmithKline Plc&#39;s  diabetes drug Avandia  similar to what was reported in a study earlier this week, the  agency confirmed on Friday.
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When people with diabetes undergo coronary artery stenting to open clogs, women are more at risk for major adverse events than men, doctors in Germany report.
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It might not just be Vioxx that carries a risk of heart problems. Scientists and European regulators say users of similar pain-relief medications also may have cause for concern.
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All studies so far provide inconsistent results about the potential heart risks of GlaxoSmithKline Plc's diabetes drug Avandia, the head of the Food and Drug Administration told lawmakers on Wednesday.
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An executive of the company that makes the diabetes drug Avandia said a researcher who was among the first to link it to heart problems would be held liable for the $4 billion GlaxoSmithKline PLC lost in stock value as a result of his findings, Dr. John B. Buse testified before congressional investigators yesterday.
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Patients given a mix of modern blood   pressure drugs are one-third less likely to develop diabetes   than those on older pills, researchers said on Wednesday.
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U.S. health officials and drugmaker GlaxoSmithKline Plc are likely to face tough questioning from lawmakers on Wednesday over their handling of data suggesting a heart risk with the widely used diabetes pill Avandia.
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-- The government's own preliminary evaluation of the diabetes pill Avandia confirms the heart risks reported in a study earlier this week and suggests that as many as 60,000 to 100,000 heart attacks might be linked to its use since it came on the market eight years ago, a leading member of Congress...
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In the month after a surprising analysis revealed possible heart risks from the blockbuster diabetes drug Avandia, reports of side effects to federal regulators tripled.
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Business & money: Europe's largest drugmaker blames safety concerns over its Avandia diabetes pill