Datasets:
NeoDiscoveryAdmin
/
NDD

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The full dataset viewer is not available (click to read why). Only showing a preview of the rows.
The dataset generation failed because of a cast error
Error code:   DatasetGenerationCastError
Exception:    DatasetGenerationCastError
Message:      An error occurred while generating the dataset

All the data files must have the same columns, but at some point there are 3 new columns ({'hla_reported_all', 'clinical_effects', 'Unnamed: 3'}) and 33 missing columns ({'netchop_score', 'pubmed_id', 'genomic_coord', 'effector_origin', 'ndd_id', 'ref', 'mutation', 'reference_name', 'length', 'presentation_method', 'tap_score', 'position', 'tumor_tissue', 'prime_rank', 'netmhcstabpan_stability', 'tcga_cancer_expression_tpm_median', 'dai_netmhcpan', 'driver_status', 'alt', 'wt_peptide', 'chromosome', 'mutation_type', 'netmhcpan_rank', 'HLA', 'eluted_ligand_match', 'assay_type', 'gene', 'tumor_type_detail', 'mt_peptide', 'response_type', 'stimulation_target', 'bigmhc_im_score', 'anchor_mutation'}).

This happened while the csv dataset builder was generating data using

hf://datasets/NeoDiscoveryAdmin/NDD/data/patient_metadata.tsv (at revision 8aacfc4cef2f7d905cd3e70882cef01b91a90895)

Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)
Traceback:    Traceback (most recent call last):
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/builder.py", line 1831, in _prepare_split_single
                  writer.write_table(table)
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/arrow_writer.py", line 714, in write_table
                  pa_table = table_cast(pa_table, self._schema)
                             ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/table.py", line 2272, in table_cast
                  return cast_table_to_schema(table, schema)
                         ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/table.py", line 2218, in cast_table_to_schema
                  raise CastError(
              datasets.table.CastError: Couldn't cast
              patient_id: string
              hla_reported_all: string
              clinical_effects: string
              Unnamed: 3: double
              -- schema metadata --
              pandas: '{"index_columns": [{"kind": "range", "name": null, "start": 0, "' + 766
              to
              {'ndd_id': Value('string'), 'patient_id': Value('string'), 'tumor_tissue': Value('string'), 'tumor_type_detail': Value('string'), 'gene': Value('string'), 'mutation_type': Value('string'), 'mutation': Value('string'), 'position': Value('string'), 'mt_peptide': Value('string'), 'wt_peptide': Value('string'), 'length': Value('int64'), 'chromosome': Value('string'), 'genomic_coord': Value('string'), 'ref': Value('string'), 'alt': Value('string'), 'HLA': Value('string'), 'response_type': Value('string'), 'assay_type': Value('string'), 'effector_origin': Value('string'), 'stimulation_target': Value('string'), 'presentation_method': Value('string'), 'netmhcpan_rank': Value('float64'), 'netmhcstabpan_stability': Value('float64'), 'prime_rank': Value('float64'), 'bigmhc_im_score': Value('float64'), 'tap_score': Value('float64'), 'netchop_score': Value('float64'), 'dai_netmhcpan': Value('float64'), 'anchor_mutation': Value('string'), 'eluted_ligand_match': Value('int64'), 'tcga_cancer_expression_tpm_median': Value('float64'), 'driver_status': Value('string'), 'pubmed_id': Value('string'), 'reference_name': Value('string')}
              because column names don't match
              
              During handling of the above exception, another exception occurred:
              
              Traceback (most recent call last):
                File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1455, in compute_config_parquet_and_info_response
                  parquet_operations = convert_to_parquet(builder)
                                       ^^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1054, in convert_to_parquet
                  builder.download_and_prepare(
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/builder.py", line 894, in download_and_prepare
                  self._download_and_prepare(
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/builder.py", line 970, in _download_and_prepare
                  self._prepare_split(split_generator, **prepare_split_kwargs)
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/builder.py", line 1702, in _prepare_split
                  for job_id, done, content in self._prepare_split_single(
                                               ^^^^^^^^^^^^^^^^^^^^^^^^^^^
                File "/src/services/worker/.venv/lib/python3.12/site-packages/datasets/builder.py", line 1833, in _prepare_split_single
                  raise DatasetGenerationCastError.from_cast_error(
              datasets.exceptions.DatasetGenerationCastError: An error occurred while generating the dataset
              
              All the data files must have the same columns, but at some point there are 3 new columns ({'hla_reported_all', 'clinical_effects', 'Unnamed: 3'}) and 33 missing columns ({'netchop_score', 'pubmed_id', 'genomic_coord', 'effector_origin', 'ndd_id', 'ref', 'mutation', 'reference_name', 'length', 'presentation_method', 'tap_score', 'position', 'tumor_tissue', 'prime_rank', 'netmhcstabpan_stability', 'tcga_cancer_expression_tpm_median', 'dai_netmhcpan', 'driver_status', 'alt', 'wt_peptide', 'chromosome', 'mutation_type', 'netmhcpan_rank', 'HLA', 'eluted_ligand_match', 'assay_type', 'gene', 'tumor_type_detail', 'mt_peptide', 'response_type', 'stimulation_target', 'bigmhc_im_score', 'anchor_mutation'}).
              
              This happened while the csv dataset builder was generating data using
              
              hf://datasets/NeoDiscoveryAdmin/NDD/data/patient_metadata.tsv (at revision 8aacfc4cef2f7d905cd3e70882cef01b91a90895)
              
              Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)

Need help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.

ndd_id
string
patient_id
string
tumor_tissue
string
tumor_type_detail
string
gene
string
mutation_type
string
mutation
string
position
string
mt_peptide
string
wt_peptide
string
length
int64
chromosome
string
genomic_coord
string
ref
string
alt
string
HLA
string
response_type
string
assay_type
string
effector_origin
string
stimulation_target
string
presentation_method
string
netmhcpan_rank
float64
netmhcstabpan_stability
float64
prime_rank
float64
bigmhc_im_score
float64
tap_score
float64
netchop_score
float64
dai_netmhcpan
float64
anchor_mutation
string
eluted_ligand_match
int64
tcga_cancer_expression_tpm_median
float64
driver_status
string
pubmed_id
string
reference_name
string
NDDR-8Y7QQTRFWC-U
GEXOATK7
Skin
Skin Cutaneous Melanoma
WDR46
SNV
p.T227I
3
FLIYLDVSV
FLTYLDVSV
9
6
33287207
G
A
HLA-A02:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC, tumor_cells
none
0.123
0.17
0.124
0.500021
0.2
0.152263
-0.198451
no
1
5.306263
null
PMID:33303615
Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer
NDDR-2HJHFX0EFJ-0
GEXOATK7
Skin
Skin Cutaneous Melanoma
AHNAK
SNV
p.S4460F
1
FMPDFDLHL
SMPDFDLHL
9
11
62526678
G
A
HLA-A02:01
CD8
ELISPOT, ICS, multimer
patient_TIL
peptide_pulsed_APC
none
0.057
0.3
0.053
0.582847
0.782
0.978539
-0.816761
no
1
4.897806
Other Tumor Driver
PMID:33303615
Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer
NDDR-M2GXDWKP1W-D
ZWHDI5GT
Skin
Skin Cutaneous Melanoma
GNB5
SNV
p.P377L
9
RVSTLRVSL
RVSTLRVSP
9
15
52124519
G
A
HLA-B07:02
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.139
0.8
0.088
0.476441
1.286
0.034531
-3.435379
no
0
0.389732
null
PMID:33303615
Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer
NDDR-JRGCAYDCQA-S
6FHDB5EK
Skin
Skin Cutaneous Melanoma
TRAPPC1
SNV
p.R129G
4
FRSGLDSYV
FRSRLDSYV
9
17
7930659
G
C
HLA-C06:02
CD8
51Cr, HLA-block
patient_Tc_line
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.1
29
0.018
0.380201
0.366
0.73499
-0.41871
no
1
5.942411
null
PMID:10582700
Two antigens recognized by autologous cytolytic T lymphocytes on a Melanoma result from a single point mutation
NDDR-VXMQ2DHCNY-F
DAXCBTFA
Skin
Skin Cutaneous Melanoma
TRAPPC1
SNV
p.R129G
7
SELFRSGLDSY
SELFRSRLDSY
11
17
7930659
G
C
HLA-B44:02
CD8
51Cr, HLA-block
patient_Tc_line
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.266
0.4
0.581
0.052169
3.04
0.763436
0.158546
no
1
5.942411
null
PMID:10582700
Two antigens recognized by autologous cytolytic T lymphocytes on a Melanoma result from a single point mutation
NDDR-AHCH9CD88T-A
M4HZA63S
Skin
Skin Cutaneous Melanoma
HERV-K-MEL
SNV
p.V102I
5
MLAVISCAV
MLAVVSCAV
9
null
null
null
null
HLA-A02:01
CD8
51Cr, HLA-block
patient_Tc_line
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
1.022
0.3
0.553
0.416587
0.378
null
-0.068993
no
0
null
null
PMID:12359761
A human endogenous retroviral sequence encoding an antigen recognized on Melanoma by cytolytic T lymphocytes
NDDR-MG2GYB7FKK-1
LFXUCEDT
Skin
Skin Cutaneous Melanoma
PRDX5
SNV
p.S79L
6
LLLDDLLVSI
LLLDDSLVSI
10
11
64321032
C
T
HLA-A02:01
CD8
51Cr, HLA-block, multimer
patient_Tc_line, patient_TIL
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.171
0.4
0.046
0.535931
0.624
0.954141
0.047913
no
1
7.68365
null
PMID:15695408
Immunogenicity without immunoselection: a mutant but functional antioxidant enzyme retained in a human metastatic Melanoma and targeted by CD8(+) T cells with a memory phenotype
NDDR-3Q45K91QR4-F
D35NTCNS
Skin
Skin Cutaneous Melanoma
MYO1B
SNV
p.E911K
1
KINKNPKYK
EINKNPKYK
9
2
191414079
G
A
HLA-A03:01
CD8
51Cr, HLA-block, multimer
patient_Tc_line, patient_TIL
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.024
0.2
0.013
0.446357
0.552
0.634706
-4.044512
no
1
3.642422
null
PMID:10064075
A natural cytotoxic T cell response in a spontaneously regressing human Melanoma targets a neoantigen resulting from a somatic point mutation
NDDR-4HG2AETK8S-9
V4WFIEVK
Lung
Non-Small Cell Lung Cancer (NSCLC)
NFYC
SNV
p.Q241K
6
AQQITKTEV
AQQITQTEV
9
null
null
null
null
HLA-B52:01
CD8
51Cr, HLA-block
patient_Tc_line
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.454
7
0.023
0.160519
0.728
null
0.260164
no
0
3.071222
null
PMID:16287085
A point mutation in the NFYC gene generates an antigenic peptide recognized by autologous cytolytic T lymphocytes on a human squamous cell lung carcinoma
NDDR-BD6M2KY4NN-4
V4WFIEVK
Lung
Non-Small Cell Lung Cancer (NSCLC)
NFYC
SNV
p.Q241K
5
QQITKTEV
QQITQTEV
8
1
40769362
C
A
HLA-B52:01
CD8
51Cr, HLA-block
patient_Tc_line
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.885
3
0.473
0.664413
0.524
null
0.162851
no
0
3.071222
null
PMID:16287085
A point mutation in the NFYC gene generates an antigenic peptide recognized by autologous cytolytic T lymphocytes on a human squamous cell lung carcinoma
NDDR-7SABVDNYFG-Y
TSXDFNM6
Head & Neck
Head and Neck Squamous Cell Carcinoma
TP53
SNV
p.Y220C
4
VVPCEPPEV
VVPYEPPEV
9
null
null
null
null
HLA-A02:01
CD8
51Cr, HLA-block
patient_Tc_line
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.751
9
1.073
0.317315
0.454
0.687508
0.629941
no
1
3.293914
Tumor Driver
PMID:17294448
Immunological characterization of missense mutations occurring within cytotoxic T cell defined p53 epitopes in HLA A0201 squamous cell carcinomas of the head and neck
NDDR-GSSA542C57-I
7LJZLSYK
Skin
Skin Cutaneous Melanoma
ENTPD4
SNV
p.P85L
7
ATDTNNLNVNY
ATDTNNPNVNY
11
8
23447838
G
A
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
none
2.391
4.5
1.282
0.364496
2.864
0.96242
0.671223
no
0
3.119629
null
PMID:33038342
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction
NDDR-SGEY1B756Q-7
7LJZLSYK
Skin
Skin Cutaneous Melanoma
TTC37
SNV
p.A692V
6
YLDGKVVDY
YLDGKAVDY
9
5
95520755
G
A
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
none
3.937
35
11.33
0.307559
2.426
null
-0.116625
no
0
3.005436
null
PMID:33038342
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction
NDDR-WSV1MDSJB6-H
TFT6DO6A
Skin
Skin Cutaneous Melanoma
ARMT1
SNV
p.P286L
2
FYGKTILWF
FPGKTILWF
9
6
151468641
C
T
HLA-A24:02
CD8
ELISPOT, ICS, multimer
PBMC_postVax
peptide_pulsed_APC
none
0.052
0.25
0.02
0.351818
2.108
null
-4.193145
no
0
2.896756
null
PMID:30880120
Identification of a neoantigen epitope in a Melanoma patient with good response to anti-PD-1 antibody therapy
NDDR-XMMWH86R9X-E
FNWFEVPE
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
PDCD10
SNV
p.A74P
4
IASPIKEL
IASAIKEL
8
3
167687680
C
G
HLA-C12:02
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
0.234
2.5
3.957
0.149582
0.99
0.48951
-1.082819
no
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-BBEYF3X3HN-4
FNWFEVPE
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
PDCD10
SNV
p.A74P
10
LQTIKDIASPI
LQTIKDIASAI
11
3
167687680
C
G
HLA-B52:01
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
7.046
0.4
10.695
0.000387
0.728
0.897295
0.649004
no
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-8FNTWKZDFG-Y
FU5SPZUA
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
TSEN54
SNV
p.R472Q
2
AQMCISGF
ARMCISGF
8
17
75523764
G
A
HLA-C12:03
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
22.864
1.2
33.066
0.003008
3.142
0.307014
-0.193672
yes
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-JDQYDNJXFT-A
FU5SPZUA
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
PCSK9
SNV
p.V202F
11
DHREIEGRVMF
DHREIEGRVMV
11
1
55052358
G
T
HLA-B18:01
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
0.158
12
1.548
0.145635
2.264
0.536006
-2.522178
no
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-0J9XF0AJTT-A
FU5SPZUA
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
PCSK9
SNV
p.V202F
1
FTDFENVP
VTDFENVP
8
1
55052358
G
T
HLA-C05:01
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
9.493
45
8.173
0.146671
-0.474
0.405231
-0.296779
no
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-0V67NT0BT2-D
FU5SPZUA
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
NEU2
SNV
p.L234T
9
KTGEQRVVTL
KTGEQRVVLL
10
2
233034587
G
A
HLA-C12:03
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
9.571
5.5
5.727
0.004257
0.814
null
-0.381034
yes
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-9A9KVDPVGD-V
FU5SPZUA
Cerebellum/Posterior fossa
Medulloblastoma (pediatric)
SVIL
SNV
p.D1285N
8
RTDVKAYNVT
RTDVKAYDVT
10
null
null
null
null
HLA-C05:01
CD8
ELISPOT, ICS, multimer
patient_Tc_line, PBMC_pre
peptide_pulsed_APC
none
12.052
31
3.575
0.175771
-0.81
0.027018
-0.39557
no
0
null
null
PMID:31351799
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy
NDDR-NB93YAHBJ0-B
4V2JUJEQ
Liver
Hepatocellular Carcinoma
C5orf42
SNV
p.I1134K
13
DADILSETFQLLK
DADILSETFQLLI
13
5
37201697
A
T
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_Tc_line
peptide_pulsed_APC
none
12.983
5.5
2.664
0.158422
null
null
-1.87901
no
0
null
null
PMID:31887370
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
NDDR-1YAP0FVN2C-U
4V2JUJEQ
Liver
Hepatocellular Carcinoma
C5orf42
SNV
p.I1134K
11
DILSETFQLLK
DILSETFQLLI
11
5
37201697
A
T
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_Tc_line
peptide_pulsed_APC
none
3.101
1.8
0.978
0.09474
0.296
null
-2.96262
no
0
null
null
PMID:31887370
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
NDDR-0T85G4PK4N-4
4V2JUJEQ
Liver
Hepatocellular Carcinoma
C5orf42
SNV
p.I1134K
10
ILSETFQLLK
ILSETFQLLI
10
5
37201697
A
T
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_Tc_line
peptide_pulsed_APC
none
0.675
0.5
0.762
0.072464
0.432
null
-3.858778
no
0
null
null
PMID:31887370
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
NDDR-JPW6QH0ZNW-D
4V2JUJEQ
Liver
Hepatocellular Carcinoma
C5orf42
SNV
p.I1134K
9
LSETFQLLK
LSETFQLLI
9
5
37201697
A
T
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre, patient_Tc_line
peptide_pulsed_APC
none
0.544
1.2
0.28
0.121928
0.316
null
-3.752958
no
0
null
null
PMID:31887370
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
NDDR-AREYVJW6QB-T
3RRUMLDF
Skin
Skin Cutaneous Melanoma
DCAKD
SNV
p.S199F
2
RFLEYLPLRF
RSLEYLPLRF
10
17
45024533
G
A
HLA-A24:02
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.104
0.12
0.187
0.367922
2.9
0.55062
-2.739599
no
1
3.732597
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-NPWGNEDF13-E
G4ZPYEDM
Skin
Skin Cutaneous Melanoma
DDX3X
SNV
p.E388K
4
FPKKIQMLA
FPKEIQMLA
9
X
41345316
G
A
HLA-B56:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.006
0.07
0.347
0.831153
-1.374
0.920179
0.405465
no
0
4.161428
Tumor Driver
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-1RZ65VX580-B
G4ZPYEDM
Skin
Skin Cutaneous Melanoma
ITGA9
SNV
p.L548P
7
VTEKLQPTY
VTEKLQLTY
9
3
37542539
T
C
HLA-A01:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.02
0.12
0.02
0.281449
2.714
0.946856
1.609438
no
0
1.3091
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-5NDTKW9WVC-U
G6DBM54G
Skin
Skin Cutaneous Melanoma
VPS16
SNV
p.S404F
5
LRAAFFGKCF
LRAASFGKCF
10
20
2862814
C
T
HLA-B27:05
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
2.327
0.8
0.612
0.411294
2.934
0.412664
-0.018732
no
0
3.703167
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-MHSQEBMGSW-D
G6DBM54G
Skin
Skin Cutaneous Melanoma
CIT
SNV
p.P2056L
4
VRTLLSQVNK
VRTPLSQVNK
10
12
119690296
G
A
HLA-B27:05
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.829
0.4
1.059
0.659847
0.756
0.817271
0.578183
no
0
0.65081
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-M431P5K4KM-3
G6DBM54G
Skin
Skin Cutaneous Melanoma
CASP1
SNV
p.P172S
8
WRNILLLSLH
WRNILLLPLH
10
11
105041480
G
A
HLA-B27:05
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
2.113
1.2
0.462
0.79588
-0.566
null
-0.025235
no
0
2.91849
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-YZD3GSV3PV-C
F3XRZQLP
Skin
Skin Cutaneous Melanoma
FAM200A
SNV
p.S116F
9
IPLSDNTIF
IPLSDNTIS
9
7
99548061
G
A
HLA-B35:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.049
0.12
0.039
0.542263
1.964
0.042772
-4.541121
yes
0
1.976985
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-QFKBAJAWPA-S
F3XRZQLP
Skin
Skin Cutaneous Melanoma
GRIN2B
SNV
p.E1104K
5
REFDKIELAY
REFDEIELAY
10
12
13563928
C
T
HLA-B41:02
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.527
2.5
0.137
0.473416
3.384
0.977014
-0.564753
no
0
-7.861448
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-3FYD6RDVNQ-7
F3XRZQLP
Skin
Skin Cutaneous Melanoma
TBX4
SNV
p.S271F
5
YPVIFKSIM
YPVISKSIM
9
17
61480110
C
T
HLA-B35:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.083
0.08
0.076
0.853465
-0.268
0.949069
0.170345
yes
0
-5.357024
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-J3PXJHBAC2-D
URSBQAUG
Skin
Skin Cutaneous Melanoma
FAM50B
SNV
p.E78K
7
DMKARQKALV
DMKARQEALV
10
6
3850043
G
A
HLA-B08:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.843
3
3.24
0.65091
0.1
0.521495
0.064934
yes
0
2.637761
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-5G69MS9MJJ-0
3RRUMLDF
Skin
Skin Cutaneous Melanoma
ACPP
SNV
p.E34K
1
KLKFVTLVF
ELKFVTLVF
9
3
132317556
G
A
HLA-A24:02
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.978
1.7
0.106
0.251486
2.69
null
-0.884714
no
0
null
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-6KW890FEY0-B
3RRUMLDF
Skin
Skin Cutaneous Melanoma
ACPP
SNV
p.E34K
1
KLKFVTLVF
ELKFVTLVF
9
3
132317556
G
A
HLA-B15:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.049
0.2
0.002
0.305979
2.69
null
-2.043074
no
0
null
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-BGT2WPZEN8-J
F3XRZQLP
Skin
Skin Cutaneous Melanoma
COL22A1
SNV
p.D291N
7
FPQGLPNEY
FPQGLPDEY
9
8
138826756
C
T
HLA-B35:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
none
0.003
0.09
0.016
0.566362
2.026
0.818258
0
yes
0
0.919263
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-51YCQP8A9M-3
F3XRZQLP
Skin
Skin Cutaneous Melanoma
COL22A1
SNV
p.D291N
3
LPNEYAFVTT
LPDEYAFVTT
10
8
138826756
C
T
HLA-B35:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
4.521
1
0.237
0.364148
-1.422
0.05056
0.028721
yes
0
0.919263
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-B7GMHB69XA-S
F3XRZQLP
Skin
Skin Cutaneous Melanoma
COL22A1
SNV
p.D291N
3
LPNEYAFVT
LPDEYAFVT
9
8
138826756
C
T
HLA-B35:01
CD8
ELISPOT
PBMC_postVax
peptide_pulsed_APC
TMC
0.923
0.5
0.19
0.718165
-1.422
0.499
-0.327767
yes
0
0.919263
null
PMID:28678778
An immunogenic personal neoantigen vaccine for patients with Melanoma
NDDR-MSZN302K7F-X
DZL67UZM
Skin
Skin Cutaneous Melanoma
CDC37L1
SNV
p.P186L
6
FLSDHLYLV
FLSDHPYLV
9
9
4697144
C
T
HLA-A02:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.002
0.01
0.001
0.734145
0.054
0.947568
0
no
1
1.396516
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-G695BNZBRH-Z
DZL67UZM
Skin
Skin Cutaneous Melanoma
DOPEY2
SNV
p.R365C
4
KPFCVLISL
KPFRVLISL
9
21
36214520
C
T
HLA-B07:02
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.239
0.12
0.015
0.649446
0.756
null
1.979956
no
0
null
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-A19KEFTKZ2-D
DZL67UZM
Skin
Skin Cutaneous Melanoma
FLNA
SNV
p.P369L
9
AGQHIAKSLF
AGQHIAKSPF
10
X
154366430
G
A
HLA-B44:02
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
4.19
18
1.837
0.036542
2.526
0.44498
-0.68512
no
0
7.162795
Other Tumor Driver
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-M93AXPJXAK-1
DZL67UZM
Skin
Skin Cutaneous Melanoma
FLNA
SNV
p.P369L
6
HIAKSLFEV
HIAKSPFEV
9
X
154366430
G
A
HLA-A02:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.107
0.4
0.045
0.38505
0.376
0.884259
-0.655047
no
1
7.162795
Other Tumor Driver
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-TSWQ8ED6V6-H
DZL67UZM
Skin
Skin Cutaneous Melanoma
KMT2C
SNV
p.P1984S
3
KPSDTPRPVM
KPPDTPRPVM
10
7
152181961
G
A
HLA-B07:02
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.015
0.1
0.161
0.534873
-0.126
0.858985
-1.120591
no
0
1.907352
Tumor Driver
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-2YDKRK2AD9-K
NGE5BUYC
Skin
Skin Cutaneous Melanoma
TTBK2
SNV
p.S1088L
9
RPHHDQRSL
RPHHDQRSS
9
15
42745988
G
A
HLA-B07:02
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.008
0.05
0.1
0.729896
0.654
0.118015
-4.77702
no
0
0.111698
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-VAPV22ZYG6-H
LC3W5VRX
Skin
Skin Cutaneous Melanoma
KIF26B
SNV
p.N256S
2
SSYTGFANK
SNYTGFANK
9
1
245367135
A
G
HLA-A11:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.007
0.3
0.006
0.334228
0.99
0.970843
-4.330733
no
0
1.124709
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-KWE7NJQDW7-I
LYXKV47S
Skin
Skin Cutaneous Melanoma
SPOP
SNV
p.N147I
7
FLLDEAIGL
FLLDEANGL
9
17
49619021
T
A
HLA-A02:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.009
0.8
0.042
0.644657
0.738
0.943178
-0.893818
no
1
2.900451
Other Tumor Driver
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-3W2VQMDDEP-6
N6T2LYFN
Skin
Skin Cutaneous Melanoma
RETSAT
SNV
p.P546S
8
HDLGRLHSC
HDLGRLHPC
9
2
85343696
G
A
HLA-B37:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
1.188
13
0.017
0.923299
-0.304
0.026627
-0.520376
no
0
4.736423
Other Tumor Driver
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-GFWC1867QW-D
N6T2LYFN
Skin
Skin Cutaneous Melanoma
RETSAT
SNV
p.P546S
2
HSCVMASLR
HPCVMASLR
9
2
85343696
G
A
HLA-A68:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.84
0.3
0.065
0.370427
1.5
0.646453
-1.071257
no
0
4.736423
Other Tumor Driver
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-KYVW6EZ6RX-E
OKQRI23E
Skin
Skin Cutaneous Melanoma
NARFL
SNV
p.E62K
1
KSQREEVRR
ESQREEVRR
9
null
null
null
null
HLA-A31:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.411
1.3
0.683
0.025452
1.666
null
-2.183067
no
0
null
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-NFN8N8118Y-F
VU5HBL4S
Skin
Skin Cutaneous Melanoma
PPFIA4
SNV
p.S709N
4
MRMNQGVCC
MRMSQGVCC
9
1
203053848
G
A
HLA-B39:06
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.418
0.09
3.039
0.972498
0.486
0.033837
0.42601
no
0
-0.786497
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-73G4NR2F2Q-7
LYXKV47S
Skin
Skin Cutaneous Melanoma
CDK4
SNV
p.R24L
2
ALDPHSGHFV
ARDPHSGHFV
10
12
57751647
C
A
HLA-A02:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.085
1.2
0.065
0.469788
0.228
0.668099
-4.919637
no
1
4.89147
Tumor Driver
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-X3SEE1T450-B
FRMBI3H3
Skin
Skin Cutaneous Melanoma
CLINT1
SNV
p.T472I
4
VSKILPSTW
VSKTLPSTW
9
5
157789479
G
A
HLA-B57:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.006
0.4
0.003
0.833897
1.018
0.903586
0
no
0
3.647901
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-19YD017ZK3-E
FRMBI3H3
Skin
Skin Cutaneous Melanoma
COX7A2
SNV
p.A84V
5
GVADVLLYR
GVADALLYR
9
6
75240339
G
A
HLA-A11:01
CD8
ELISPOT, ICS
PBMC_postVax
peptide_pulsed_APC
none
0.021
0.3
0.004
0.744459
1.534
0.159054
-0.619039
no
0
5.434168
null
PMID:28678784
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
NDDR-B1DKTHN336-H
5DJDBZPW
Skin
Skin Cutaneous Melanoma
SYTL4
SNV
p.S363F
6
GRIAFFLKY
GRIAFSLKY
9
X
100687163
G
A
HLA-B27:05
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
MS
0.009
0.4
0.001
0.914394
3.272
0.977758
0.117783
no
1
-2.573045
null
PMID:27869121
Direct identification of clinically relevant neoepitopes presented on native human Melanoma tissue by mass spectrometry
NDDR-VZ6AX01GXJ-0
5DJDBZPW
Skin
Skin Cutaneous Melanoma
NCAPG2
SNV
p.P333L
2
KLILWRGLK
KPILWRGLK
9
7
158680743
G
A
HLA-A03:01
CD8
ELISPOT
patient_TIL
peptide_pulsed_APC
MS
0.184
0.4
0.122
0.435756
0.762
0.861472
-3.519785
no
1
2.653482
null
PMID:27869121
Direct identification of clinically relevant neoepitopes presented on native human Melanoma tissue by mass spectrometry
NDDR-PBXJS7YJDT-A
5DJDBZPW
Skin
Skin Cutaneous Melanoma
AKAP6
SNV
p.M1482I
6
KLKLPIIMK
KLKLPMIMK
9
14
32822259
G
C
HLA-A03:01
CD8
ELISPOT
patient_TIL
peptide_pulsed_APC
MS
0.006
0.12
0.001
0.468706
0.62
0.968833
-0.154151
no
1
-0.385819
null
PMID:27869121
Direct identification of clinically relevant neoepitopes presented on native human Melanoma tissue by mass spectrometry
NDDR-WKQY9KFRV9-K
PKPFBJDF
Skin
Skin Cutaneous Melanoma
NOP16
SNV
p.P169L
9
SPGPVKLEL
SPGPVKLEP
9
5
176384171
G
A
HLA-B07:02
CD8
ELISPOT
patient_TIL
peptide_pulsed_APC
MS
0.011
0.7
0.028
0.235061
0.112
null
-4.500819
no
1
2.721895
null
PMID:27869121
Direct identification of clinically relevant neoepitopes presented on native human Melanoma tissue by mass spectrometry
NDDR-C98AVT8VA9-K
I4HS6WN2
Skin
Skin Cutaneous Melanoma
CSNK1A1
SNV
p.S27L
2
GLFGDIYLA
GSFGDIYLA
9
5
149550885_149550886
TC
CT
HLA-A02:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.052
1.5
0.046
0.590849
-0.414
0.312295
-4.006284
no
1
3.029707
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-FF8XNFEPVF-X
74LV6E74
Skin
Skin Cutaneous Melanoma
MATN2
SNV
p.E226K
1
KTLTSVFQK
ETLTSVFQK
9
8
97931486
G
A
HLA-A11:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.004
0.01
0.001
0.441139
0.686
0.926989
-3.102342
no
1
2.156137
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-894FCPT0FK-1
74LV6E74
Skin
Skin Cutaneous Melanoma
CDK12
SNV
p.E928K
5
CILGKLFTK
CILGELFTK
9
7
40063036
G
A
HLA-A11:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.279
1.1
0.021
0.14316
0.56
0.34099
-0.327213
no
1
2.569549
Tumor Driver
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-AYRXPFMZNE-W
74LV6E74
Skin
Skin Cutaneous Melanoma
CDK12
SNV
p.E928K
5
CILGKLFTKK
CILGELFTKK
10
7
40063036
G
A
HLA-A11:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
1.908
1.2
0.466
0.20399
0.56
0.794302
0.048869
no
0
2.569549
Tumor Driver
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-YRY5RYAEAT-A
I4HS6WN2
Skin
Skin Cutaneous Melanoma
CSNK1A1
SNV
p.S27L
2
GLFGDIYLAI
GSFGDIYLAI
10
5
149550885_149550886
TC
CT
HLA-A02:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.369
0.8
0.185
0.573459
0.656
0.921601
-3.064454
no
1
3.029707
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-EMJNAQ3KAZ-G
I4HS6WN2
Skin
Skin Cutaneous Melanoma
HAUS3
SNV
p.T160A
7
ILNAMIAKI
ILNAMITKI
9
4
2240469
T
C
HLA-A02:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.43
0.5
0.15
0.647834
0.322
0.879551
0.750579
no
1
0.52195
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-BGR5R73328-J
74LV6E74
Skin
Skin Cutaneous Melanoma
MATN2
SNV
p.E226K
1
KTLTSVFQKK
ETLTSVFQKK
10
8
97931486
G
A
HLA-A11:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.054
0.01
0.069
0.448778
0.686
0.963817
-2.580497
no
0
2.156137
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-545JRB33M5-G
J5PM7M2Y
Skin
Skin Cutaneous Melanoma
PLEKHM2
SNV
p.H1005Y
10
LTDDRLFTCY
LTDDRLFTCH
10
1
15732428
C
T
HLA-A01:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.009
0.01
0.006
0.695479
2.652
0.412145
-4.333653
no
0
5.051104
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-F477MEXVTB-T
I4HS6WN2
Skin
Skin Cutaneous Melanoma
GAS7
SNV
p.H225Y
9
SLADEAEVYL
SLADEAEVHL
10
17
9934186
G
A
HLA-A02:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.095
2.5
0.045
0.343229
1.054
0.969244
-0.408968
no
1
5.458259
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-1NGBH26P25-G
J5PM7M2Y
Skin
Skin Cutaneous Melanoma
PPP1R3B
SNV
p.P176H
5
YTDFHCQYV
YTDFPCQYV
9
8
9141125
G
T
HLA-A01:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC
none
0.224
1.3
0.005
0.684944
-0.158
0.901694
-0.117783
no
1
2.600531
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-3397S1P89B-T
J5PM7M2Y
Skin
Skin Cutaneous Melanoma
PPP1R3B
SNV
p.P176H
5
YTDFHCQYVK
YTDFPCQYVK
10
8
9141125
G
T
HLA-A01:01
CD8
ELISPOT, ICS
patient_TIL
peptide_pulsed_APC, tumor_cells
endogenous(HLA-block)
0.841
1.2
0.145
0.480959
-0.008
0.912707
0.144291
no
1
2.600531
null
PMID:23644516
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
NDDR-4H8V6XSZ4F-X
6K4YGFNF
Skin
Skin Cutaneous Melanoma
KIF16B
SNV
p.L1009P
2
APARLERRHSA
ALARLERRHSA
11
20
16378976
A
G
HLA-B07:02
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.459
0.7
2.211
0.022523
-0.818
0.78183
-3.671241
no
0
1.905253
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-1C3G4QSC15-G
6K4YGFNF
Skin
Skin Cutaneous Melanoma
FLNA
SNV
p.R2049C
1
CVRVSGQGL
RVRVSGQGL
9
X
154353082
G
A
HLA-B07:02
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
1.384
1.8
0.386
0.063144
1.114
0.953143
2.305479
no
0
7.162795
Other Tumor Driver
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-Y4RAXRTAQJ-0
OGN36M6H
Skin
Skin Cutaneous Melanoma
KIF1BP
SNV
p.P246S
4
AYHSIEWAI
AYHPIEWAI
9
null
null
null
null
HLA-A24:02
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.206
0.2
0.121
0.155517
1.012
null
0.873529
no
0
null
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-1N2HY69Q10-B
OGN36M6H
Skin
Skin Cutaneous Melanoma
KIF1BP
SNV
p.P246S
6
HNAYHSIEWA
HNAYHPIEWA
10
null
null
null
null
HLA-B38:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
33.333
39
3.253
0.02842
-0.71
null
0.165808
no
0
null
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-D73BQ8XHHP-6
OGN36M6H
Skin
Skin Cutaneous Melanoma
KIF1BP
SNV
p.P246S
7
EHNAYHSIEWA
EHNAYHPIEWA
11
null
null
null
null
HLA-B38:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
3.934
31
3.421
0.07076
-1.148
null
0.12205
no
0
null
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-ZQ6KEKP7NG-Y
OGN36M6H
Skin
Skin Cutaneous Melanoma
KIF1BP
SNV
p.P246S
5
NAYHSIEWAI
NAYHPIEWAI
10
null
null
null
null
HLA-C12:03
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
7.444
11
3.759
0.021691
1.216
null
0.500668
yes
0
null
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-KQX0BHDE2V-C
OGN36M6H
Skin
Skin Cutaneous Melanoma
KIF1BP
SNV
p.P246S
3
YHSIEWAI
YHPIEWAI
8
10
69005862
C
T
HLA-B38:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.184
0.5
0.142
0.479906
0.332
null
-0.240385
no
0
null
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-WYJW76M06R-8
TOGZJCOT
Skin
Skin Cutaneous Melanoma
PDS5A
SNV
p.Y1000F;H1007Y
1,8
FVVPYMIYLL
YVVPYMIHLL
10
null
null
null
null
HLA-C03:03
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
4.104
4.5
0.127
0.088732
0.976
0.971609
1.044545
yes
0
3.19243
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-XJ3RMEC41A-S
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MAGEA6
SNV
p.E168K
1
KVDPIGHVY
EVDPIGHVY
9
X
152767149
C
T
HLA-A01:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.011
0.02
0.006
0.538203
2.85
0.975792
0.606136
no
0
2.919136
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-BS3218G751-C
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MAGEA6
SNV
p.E168K
1
KVDPIGHVYIF
EVDPIGHVYIF
11
null
null
null
null
HLA-C05:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.207
20
0.147
0.218765
2.46
0.972332
-1.486205
no
0
2.919136
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-YXV2AQ4573-E
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MAGEA6
SNV
p.E168K
3
LMKVDPIGHVY
LMEVDPIGHVY
11
null
null
null
null
HLA-B15:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.178
0.04
0.557
0.094909
3.084
0.975792
-1.548041
no
0
2.919136
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-0CQM64X89C-U
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MED13
SNV
p.P1691S
6
SVQIISCQY
SVQIIPCQY
9
null
null
null
null
HLA-A30:02
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.122
2.5
0.031
0.996467
3.044
0.965587
0.541341
no
0
2.53319
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-8V8HWA94GP-6
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MED13
SNV
p.P1691S
5
VQIISCQY
VQIIPCQY
8
17
61961773
G
A
HLA-A30:02
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
1.365
4
11.228
0.965486
3.326
0.965587
0.328301
no
0
2.53319
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-R8DTB8R876-H
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MED13
SNV
p.P1691S
5
VQIISCQY
VQIIPCQY
8
17
61961773
G
A
HLA-B15:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.34
0.12
0.377
0.395824
3.326
0.965587
0.102098
no
0
2.53319
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-NG120S2XBY-F
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MED13
SNV
p.P1691S
7
VSVQIISCQY
VSVQIIPCQY
10
null
null
null
null
HLA-A30:02
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.491
3.5
1.446
0.992012
3.218
0.965587
-0.085823
no
0
2.53319
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-HHJP6E4WJE-W
TOGZJCOT
Skin
Skin Cutaneous Melanoma
MED13
SNV
p.P1691S
7
VSVQIISCQY
VSVQIIPCQY
10
null
null
null
null
HLA-A01:01
CD8
multimer, ELISPOT
PBMC_pre, patient_TIL
peptide_pulsed_APC, TMC_minigene
TMC
0.715
0.12
1.623
0.058955
3.218
0.965587
0.035591
no
0
2.53319
null
PMID:26901407
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of Melanoma patients
NDDR-NS03YKG0DA-S
DYEDTPM2
Ovary
Ovarian Cancer
HLA-DRB1
SNV
p.I248L
8
FLGAGLFLYF
FLGAGLFIYF
10
6
32580767
T
G
HLA-A02:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
5.948
4
0.317
0.389814
1.956
0.838477
0.003537
no
0
8.017807
Other Tumor Driver
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-NATBNFYEAK-1
YQSS3IYL
Ovary
Ovarian Cancer
HS6ST1
SNV
p.S405I
4
DYMIHIIEKW
DYMSHIIEKW
10
2
128268184
C
A
HLA-A23:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.328
0.9
0.215
0.596565
0.846
0.959502
0.291755
no
0
4.582285
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-BHHDNDR6ZQ-7
VMHDDH4X
Ovary
Ovarian Cancer
COPG2
SNV
p.T37I
1
IPINPRRCL
TPINPRRCL
9
7
130666910
G
A
HLA-B07:02
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.025
0.06
0.434
0.808351
0.486
0.764573
0.083382
no
0
3.153886
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-FQESYTA52V-C
BFEZW33V
Ovary
Ovarian Cancer
EBF4
SNV
p.I510S
2
ASMPSSPPL
AIMPSSPPL
9
20
2755627
T
G
HLA-B15:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
2.235
1.8
2.416
0.00976
1.436
0.957767
0.549599
no
0
2.825521
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-PZTTJ71JFS-9
BFEZW33V
Ovary
Ovarian Cancer
TRIM26
SNV
p.G497W
5
LDYEWGTVTF
LDYEGGTVTF
10
6
30186007
C
A
HLA-B15:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
4.054
5.5
0.619
0.439684
2.696
0.975767
0.273801
no
1
4.100179
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-1V9MW00YAR-8
BFEZW33V
Ovary
Ovarian Cancer
DCHS1
SNV
p.P141L
9
VADINDHAL
VADINDHAP
9
null
null
null
null
HLA-C03:03
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.078
11
0.047
0.677865
0.722
0.050902
-5.09838
yes
0
0.489337
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-RABCTRZ18B-T
TKJU56TT
Ovary
Ovarian Cancer
SEPT9
SNV
p.R289H
7
SILEQMHRK
SILEQMRRK
9
null
null
null
null
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.02
0.6
0.128
0.189973
0.682
null
-1.848455
no
1
null
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-81PF6HAJE6-H
Q2ITNIFI
Ovary
Ovarian Cancer
PDPN
SNV
p.G222C
3
FICAIIVVV
FIGAIIVVV
9
1
13614365
G
T
HLA-A02:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
1.217
0.4
0.024
0.68459
0.196
0.680153
0.893544
no
0
2.404058
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-WAWJVEYCNM-3
Q2ITNIFI
Ovary
Ovarian Cancer
KIR2DS4
SNV
p.I7S
1
SMACVGFFL
IMACVGFFL
9
null
null
null
null
HLA-A02:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
1.021
1.9
0.068
0.363276
1.164
0.623868
-0.075436
no
0
-5.058894
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-S6WF724CZW-D
TRB3HZII
Ovary
Ovarian Cancer
HHAT
SNV
p.L75F
8
KQWLVWLFL
KQWLVWLLL
9
1
210387531
C
T
HLA-A02:06
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
1.055
5.5
0.42
0.288659
1.67
0.883886
0.211365
no
1
-0.311327
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-B9FTPHZX9N-4
GNQ75CJK
Ovary
Ovarian Cancer
USP47
SNV
p.V170L
5
TSDYLSQSY
TSDYVSQSY
9
11
11892058
G
C
HLA-A01:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.002
0.4
0.004
0.252534
2.636
0.971324
0
no
0
0.7376
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-249DDXWAEX-E
Q2CMUUIO
Ovary
Ovarian Cancer
ZCCHC11
SNV
p.P1265H
8
GRKLFGTHF
GRKLFGTPF
9
1
52445815
G
T
HLA-B27:05
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.083
1
0.002
0.858419
2.74
null
-1.036481
no
0
null
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-7HYKQEP4CF-X
Q2CMUUIO
Ovary
Ovarian Cancer
TP53
SNV
p.A159V
4
RVRVMAIYK
RVRAMAIYK
9
17
7675136
G
A
HLA-A11:01
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.275
0.12
0.109
0.363579
0.902
0.656203
0.682297
no
1
4.590099
Other Tumor Driver
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
NDDR-P8JN2PCQXP-6
Q2CMUUIO
Ovary
Ovarian Cancer
OR2T3
SNV
p.C132Y
2
VYRPLHYPLL
VCRPLHYPLL
10
1
248473745
G
A
HLA-C07:02
CD8
ELISPOT, ICS, multimer
PBMC_pre
peptide_pulsed_APC
none
0.997
17
0.801
0.914976
1.256
0.853258
-0.911263
no
0
-9.965784
null
PMID:29545564
Sensitive and frequent identification of high avidity neo-epitope specific CD8?+?T cells in immunotherapy-naive ovarian cancer
End of preview.