 cross-over interventional treatment by proposing a concept of "deformation index(DI)". And, Trying to evaluate primarily the significances of such deformation. There were 53 bifurcation lesions treated by cross-over technique. All the diameter of side branch was >2.0 mm. Proposing the concept of DI as (MaxD-MinD)/MaxD (MaxD, Maximum Diameter; MinD: Minimum Diameter) to present the morphological changes of SB ostium which was measured by IVUS. The DI will be 0 theoretically for a regular round and tend to be a ellipse if close to 1. Comparison analysis the ID of SB pre and post MV stenting and try to observing the effective factor of it and relationship with quantitative coronary angiography (QAG) in coronary bifurcation intervention. The DI of SB before and after MV stenting was 0.18 ± 0.13 and 0.26 ± 0.16(P < 0.01) respectively , DI was one of correlative factors of MinD of SB ostium measured by QAG (CO:-0.103; P = 0.015). DI was still the independent factor with QCA- MinD of SB by using partial correlation analysis (P = 0.002) when other relative factors were controlled well. Ostium of SB showed a obviously ellipse trend after MV stenting in coronary bifurcation interventional treatment. DI was one of relatives of QCA-MinD of SB after procedure and may be one the causes of aggressive QCA-MinD of SB after interventional therapy using cross-over strategy in coronary bifurcation lesion.

Curcumin potentiates the anti-arthritic effect of prednisolone in Freund's complete adjuvant-induced arthritic rats.
The present study was aimed at investigating the effect of curcumin in combination with prednisolone for the effective treatment of arthritis with reduced side effects when glucocorticoids therapy is indicated. Arthritis was induced in wistar rats by subplantar injection of Freund's complete adjuvant, and animals were observed for the symptoms of arthritis during the period of 21 days. Combined treatment of curcumin with various doses of prednisolone (1.25, 2.5 and 5 mg/kg) was evaluated in order to ascertain the