 training in SLP graduate programs.

The survey described in this article was supported by the National Institute on Deafness and Other Communication Disorders, R15DC014566, of the National Institutes of Health. The author would like to thank Dr. Ellen Cohn for reviewing the survey and providing feedback on the content. In addition, the author would like to thank Mr. Michael Towey for emailing the Qualtrics survey link to attendees of the Waldo County General Hospital Speech-Language Pathology Telepractice Training program in Maine, USA. Finally, the author would like to thank Ms. Elizabeth Fedak and Ms. Kaeli MacArthur for helping to prepare the survey, organize the results, and present the findings at the Pennsylvania Speech-Language-Hearing Association Conference in 2017.


1. Introduction {#sec1-ijms-21-03421}
===============

Since the Transient Receptor Potential Vanilloid 1 (TRPV1) ion channel was cloned in the last years of the 20th century \[[@B1-ijms-21-03421]\], there have been extensive efforts to reveal the structural and functional details of this protein. Thus, nowadays it is one of the best characterized members of the TRP family of ion channels.

TRPV1 is mainly expressed by trigeminal ganglion (TG) neurons and by small-diameter neurons within sensory ganglia such as the dorsal root ganglion (DRG). It was first reported to be polymodal, responding to stimuli of different natures such as noxious heat (\>43 °C) and capsaicin, the pungent compound present in hot chili peppers that functions as a chemical agonist of the channel, eliciting pain-associated behaviors in animals and pain in humans \[[@B2-ijms-21-03421]\]. Soon after, it was shown that TRPV1 is also activated by low extracellular pH (pH ≤ 5.9). It is important to consider that when several stimuli are present together, TRPV1 activation is potentiated \[[@B2-ijms-21-03421]\].

Several more agonists for this channel have been described and have been reviewed elsewhere \[[@B3-ijms-21-03421],[@B4-ijms-21-03421],[@B5-ijms-21-03421],[@B6-ijm