stablish the safety of the recommended moisturizer in neonatesTo investigate the presence of allergies, skin condition, serum immunoglobulin E (IgE), and thymus and activation-regulated chemokine (TARC) levels in neonates

Trial design {#Sec6}
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This study is an assessor-blinded, randomized controlled, parallel-group comparison study (comparing our educational program group with an established childbirth education group) conducted in Chiba Aiyu-kai Kinen Hospital (hereafter referred to as "our hospital") to examine the superiority of the educational program over established programs. Subjects are randomized in a 1:1 ratio into one of the two groups. The participants and study personnel are not blinded with respect to the assignments.

This protocol is written in accordance with the Standard Protocol Item: Recommendations for Interventional Trials (SPIRIT) guideline. Trial registration is through the University Hospital Medical Information Network -- Clinical Trials Registry (UMIN-CTR) (UMIN000034730).

Participants {#Sec7}
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### Recruitment procedure {#Sec8}

Participants are recruited among all pregnant women who visit our hospital for consultation regarding delivery. The investigator meets with each pregnant woman to provide oral and written information on the study and to request participation. Participants are selected according to the eligibility criteria. The pregnant women discuss participation with their respective families, and those who agree to participate in the study provide informed consent. After the collection of consent forms, the participants are randomized to one of two groups.

### Eligibility criteria {#Sec9}

Eligibility and exclusion criteria are as follows:

Eligibility criteria (individuals must meet two criteria): Those planning to give birth in our hospitalThose planning to attend the childbirth education program provided by our hospital

Exclusion criteria (any of the following criteria): Those who were not planning to give birth in our hospitalBirth of triplets