CRP (normal 3.0 mg/L) is increased in patients with COVID-19. Likewise, after infection, the cytokine storm increases the fibrinogen levels in the blood; this makes the erythrocytes adhere together, increasing the ESR during times of infection. Aside from the changes in the blood portfolio, LDH, a common component of cells of various organs, is increased in COVID-19. The normal blood LDH level is 140-280 units/L, but when the cells or tissues are damaged, LDH is released into the serum, increasing its levels. Hence LDH is used as a test to detect cell or tissue injury. Like LDH, procalcitonin is normally negligible in the blood (0.01 μg/L) but increases once stimulated by cytokines. The lungs and liver also produce procalcitonin as a response to inflammatory cytokines. These processes increase the levels of procalcitonin in the blood upon infection or injury. This is concomitant with increased levels of AST and ALT, indicating liver damage. Since many reports have observed kidney and liver injury in patients with COVID-19, these markers could thus be elevated ([Supplementary Table 2](#S1){ref-type="supplementary-material"}). The changes in the levels of these components suggest that COVID-19 may be involved with damage to various tissues and cells in the body. It is imperative to closely monitor the changes in these parameters to uncover early biomarkers of COVID-19. Changes in levels of these cells and molecules may happen well in advance of the onset of typical COVID-19 symptoms. Moreover, a deeper understanding of the changes in these parameters will aid in the development of therapies for COVID-19. Further investigation is needed in this area for a better understanding of these abnormalities in blood parameters to provide accurate therapeutic drugs for COVID-19.

CURRENT TREATMENT OPTIONS UNDER STUDY
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According to WHO, based on evidence from laboratory, animal, and clinical studies, the drugs which are advised for treatment of COVID-19 are Remdesivir, Lopinavir/Ritonavir